Author details

Full Name

MickaÃ«l Canouil

Affiliation

ORCID

Career Start Year

2017

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37137910	Identification of biomarkers for glycaemic deterioration in type 2 diabetes.	Nat Commun	2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37659411	High morbidity and mortality in children with untreated congenital deficiency of leptin or its receptor.		2023
37638789	Identification of myokines susceptible to improve glucose homeostasis after bariatric surgery.		2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
36822744	Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study.		2023
35220425	Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.	Hum Mol Genet	2022
35806330	Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates.	International Journal of Molecular Sciences	2022
35427775	Epigenetic changes associated with hyperglycaemia exposure in the longitudinal D.E.S.I.R. cohort.		2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35106505	Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study.	Cell Rep Med	2022
35104326	Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies.	Diabetes Care	2022
35061034	Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan.		2022
34759311	Elevated circulating follistatin associates with an increased risk of type 2 diabetes.	Nat Commun	2021
33910978	SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations.	Science Translational Medicine	2021
34116986	Epigenome-Wide Association Study Reveals Methylation Loci Associated With Offspring Gestational Diabetes Mellitus Exposure and Maternal Methylome.	Diabetes Care	2021
33730570	Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.	Cell Reports	2021
33242514	Monogenic diabetes characteristics in a transnational multicenter study from Mediterranean countries.	Diabetes Research and Clinical Practice	2021
34661078	Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants.	ACS Pharmacol Transl Sci	2021
31388097	The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward.	International Journal of Obesity	2020
32410704	Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect.	Clinical Epigenetics	2020
31834638	General regression model: A "model-free" association test for quantitative traits allowing to test for the underlying genetic model.	Annals of Human Genetics	2020
33046911	Pathogenic variants in actionable MODY genes are associated with type 2 diabetes.	Nat Metab	2020
33264613	Persistent or Transient Human Î² Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.	Cell Reports	2020
31504159	NACHO: an R package for quality control of NanoString nCounter data.		2020
31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Nat Genet	2019
31700171	Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.	Nature Medicine	2019
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
30956117	Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes.	Mol Metab	2019
31263163	Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals.	Sci Rep	2019
29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Am J Hum Genet	2018
30154102	Type 2 diabetes-associated variants of the MT<sub>2</sub> melatonin receptor affect distinct modes of signaling.	Sci Signal	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
29963075	Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose.	Frontiers in Genetics	2018
29912962	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.	PLoS One	2018
29728363	Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes.		2018
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
28228143	Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach.	BMC Medicine	2017
28132686	Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.	American Journal of Human Genetics	2017
27999105	Hepatic DPP4 DNA Methylation Associates With Fatty Liver.		2017
28580277	Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.	Molecular Metabolism	2017
28628672	Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles.	PLoS ONE	2017