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Author Details

Hans-Heinrich Hoffmann
The Rockefeller University
2008
59
32
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36049612IL-6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease.J Hepatol2023
38076887Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.bioRxiv2023
38096415Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies.Proc Natl Acad Sci U S A2023
37563206Author Correction: Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.Commun Biol2023
36992196Characterization of Live-Attenuated Powassan Virus Vaccine Candidates Identifies an Efficacious Prime-Boost Strategy for Mitigating Powassan Virus Disease in a Murine Model.Vaccines (Basel)2023
36538032Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.Science2023
36565697Clonal replacement sustains long-lived germinal centers primed by respiratory viruses.Cell2023
34896863Flavivirus-host interactions: an expanding network of proviral and antiviral factors.Curr Opin Virol2022
35576468The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.Proc Natl Acad Sci U S A2022
35447092Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.Immunity2022
36451809A minimally-edited mouse model for infection with multiple SARS-CoV-2 strains.Front Immunol2022
36245045Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.Commun Biol2022
36130725Common human genetic variants of APOE impact murine COVID-19 mortality.Nature2022
35132412Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins.bioRxiv2022
35043109The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies.Res Sq2022
33382968Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.Cell2021
33544838Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine.J Exp Med2021
34851166Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals.mSphere2021
34648371Replication and single-cycle delivery of SARS-CoV-2 replicons.Science2021
34547765Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy.Nature2021
34834920A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.Viruses2021
34075373Fc-engineered antibody therapeutics with improved efficacy against COVID-19.Res Sq2021
34126625Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection.Nature2021
34100013Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year.bioRxiv2021
33338421TMEM41B Is a Pan-flavivirus Host Factor.Cell2021
33443154E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.Proc Natl Acad Sci U S A2021
33442697Self-organized stem cell-derived human lung buds with proximo-distal patterning and novel targets of SARS-CoV-2.bioRxiv2021
32511384Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals.bioRxiv2020
33112236Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.Elife2020
33052348TMEM41B is a pan-flavivirus host factor.bioRxiv2020
33052332Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.bioRxiv2020
32692348Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.J Exp Med2020
32577658Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.bioRxiv2020
32972996Autoantibodies against type I IFNs in patients with life-threatening COVID-19.Science2020
32743579Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.bioRxiv2020
32709745RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology.Proc Natl Acad Sci U S A2020
32704094LY6E impairs coronavirus fusion and confers immune control of viral disease.Nat Microbiol2020
32694732Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism.Nat Metab2020
32555388Convergent antibody responses to SARS-CoV-2 in convalescent individuals.Nature2020
30643282IFITM3 directly engages and shuttles incoming virus particles to lysosomes.Nat Chem Biol2019
31652305Investigating the functional link between TMEM165 and SPCA1.Biochem J2019
31270247Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines.J Exp Med2019
29249360Intrinsic Immunity Shapes Viral Resistance of Stem Cells.Cell2018
30355490NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus.Cell Rep2018
29395325Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.Cell2018
29192196A robust cell culture system supporting the complete life cycle of hepatitis B virus.Sci Rep2017
28329704The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.Immunity2017
29024641Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.Cell Host Microbe2017
27128351Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies.Virology2016
27899441Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion.J Exp Med2016
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Collaborators

Rockefeller University
Co-authored papers 49
The Rockefeller University
Co-authored papers 13
The Rockefeller University
Co-authored papers 12
The Rockefeller University
Co-authored papers 12
Rockefeller University
Co-authored papers 7
The Rockefeller University
Co-authored papers 6
Laura and Isaac Perlmutter Cancer Center
Co-authored papers 6
Acibadem Mehmet Ali Aydinlar University
Co-authored papers 4
The Rockefeller University
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
University of North Carolina
Co-authored papers 3
Yale School of Medicine
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Co-authored papers 3
Boston University Chobanian and Avedisian School of Medicine
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Ecole Polytechnique Federale de Lausanne
Co-authored papers 2
Co-authored papers 2
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 2
Institute of Systems Biology, University of Washington
Co-authored papers 2
Universidad de La Sabana
Co-authored papers 2
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
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Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Merck & Co., Inc.
Co-authored papers 1
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The Rockefeller University
Co-authored papers 1