Author details

Full Name

Charles E Foulds

Affiliation

ORCID

Career Start Year

1997

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37071495	Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer.	Cancer Res	2023
34782721	Correction to: Hormonal modulation of ESR1 mutant metastasis.	Oncogene	2022
34711608	Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer.	Cancer Res	2021
33177154	Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.	Mol Cancer Ther	2021
32668201	Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes.	Mol Cell	2020
32142667	Neurofibromin Is an Estrogen Receptor-Î± Transcriptional Co-repressor in Breast Cancer.	Cancer Cell	2020
32362585	The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells.	Mol Pharmacol	2020
31939706	Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin.	Environmental Health Perspectives	2020
32385268	Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood.	Nature Communications	2020
31710612	Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells.	PLoS ONE	2019
31672983	The Signaling Pathways Project, an integrated 'omics knowledgebase for mammalian cellular signaling pathways.	Sci Data	2019
29775582	SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription.	Mol Cell	2018
30456381	CARM1 methylates MED12 to regulate its RNA-binding ability.	Life Sci Alliance	2018
30082387	Disrupting a negative feedback loop drives endocrine therapy-resistant breast cancer.	Proceedings of the National Academy of Sciences of the United States of America	2018
29615789	Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.	Nature	2018
29748621	Proteomic profiling identifies key coactivators utilized by mutant ERÎ± proteins as potential new therapeutic targets.	Oncogene	2018
29122461	Histone Marks in the 'Driver's Seat': Functional Roles in Steering the Transcription Cycle.	Trends Biochem Sci	2017
28717009	Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation.	J Biol Chem	2017
28844863	Structural and Functional Impacts of ER Coactivator Sequential Recruitment.	Mol Cell	2017
28524171	Endocrine-disrupting chemicals and fatty liver disease.	Nature Reviews Endocrinology	2017
26487511	The Dual Estrogen Receptor Î± Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	Mol Pharmacol	2016
27219490	Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk.	Mol Endocrinol	2016
26362934	Long Noncoding RNAs as Targets and Regulators of Nuclear Receptors.	Curr Top Microbiol Immunol	2016
26487680	SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis.	Proc Natl Acad Sci U S A	2015
25728767	Structure of a biologically active estrogen receptor-coactivator complex on DNA.	Mol Cell	2015
23550157	RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators.	Proc Natl Acad Sci U S A	2013
23850489	Proteomic analysis of coregulators bound to ERÎ± on DNA and nucleosomes reveals coregulator dynamics.	Mol Cell	2013
22505454	ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.	J Clin Invest	2012
20219889	Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene.	Mol Endocrinol	2010
17435748	DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.	Nat Cell Biol	2007
15572696	Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment.	Molecular and Cellular Biology	2004
9171103	Analysis of the human TATA binding protein promoter and identification of an ets site critical for activity.	Nucleic Acids Research	1997