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Author Details
Full Name
Janet M Young
Affiliation
Fred Hutchinson Cancer Research Center
ORCID
Career Start Year
1999
Papers
50
H Index
32
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37745568
The diverse evolutionary histories of domesticated metaviral capsid genes in mammals.
bioRxiv
2023
35099534
Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline.
Mol Biol Evol
2022
35365639
A functional map of HIV-host interactions in primary human T cells.
Nat Commun
2022
33373584
Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.
Mol Cell
2021
34282725
An actin-related protein that is most highly expressed in <i>Drosophila</i> testes is critical for embryonic development.
Elife
2021
32238588
Antiviral Activity and Adaptive Evolution of Avian Tetherins.
J Virol
2020
33169670
Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in <i>Drosophila</i>.
Elife
2020
33063663
A natural variant of the essential host gene <i>MMS21</i> restricts the parasitic 2-micron plasmid in <i>Saccharomyces cerevisiae</i>.
Elife
2020
32353859
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Nature
2020
30991417
Killer Meiotic Drive and Dynamic Evolution of the wtf Gene Family.
Mol Biol Evol
2019
31841515
Hybridization promotes asexual reproduction in Caenorhabditis nematodes.
PLoS Genet
2019
31574080
Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins.
PLoS Biol
2019
29549088
Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals.
Genome Res
2018
28631612
<i>wtf</i> genes are prolific dual poison-antidote meiotic drivers.
Elife
2017
28512238
Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin.
Genes Dev
2017
26903634
Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9.
Proc Natl Acad Sci U S A
2016
28087716
The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila.
Genes Dev
2016
27481326
A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster.
Elife
2016
27198230
Evolution of a transcriptional regulator from a transmembrane nucleoporin.
Genes Dev
2016
26216977
Baculovirus protein PK2 subverts eIF2α kinase function by mimicry of its kinase domain C-lobe.
Proc Natl Acad Sci U S A
2015
26658285
Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction.
PLoS Pathog
2015
24875882
Rapid evolution of PARP genes suggests a broad role for ADP-ribosylation in host-virus conflicts.
PLoS Genet
2014
25211013
Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency.
PLoS Genet
2014
23593020
Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD.
PLoS Genet
2013
24278031
DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis.
PLoS Genet
2013
22209328
DUX4 activates germline genes, retroelements, and immune mediators: implications for facioscapulohumeral dystrophy.
Dev Cell
2012
23045604
Extensive evolutionary and functional diversity among mammalian AIM2-like receptors.
J Exp Med
2012
22541669
miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells.
Skelet Muscle
2012
22085861
Rigorous and thorough bioinformatic analyses of olfactory receptor promoters confirm enrichment of O/E and homeodomain binding sites but reveal no new common motifs.
BMC Genomics
2011
19952141
Extreme variability among mammalian V1R gene families.
Genome Res
2010
20844586
A candidate subspecies discrimination system involving a vomeronasal receptor gene with different alleles fixed in M. m. domesticus and M. m. musculus.
PLoS One
2010
18952852
Comparative sequence analysis of primate subtelomeres originating from a chromosome fission event.
Genome Res
2009
19773449
Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer.
Cancer Res
2009
19505295
Tissue-specific variation in DNA methylation levels along human chromosome 1.
Epigenetics Chromatin
2009
18632612
Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients.
Cancer Res
2008
18674749
Extensive copy-number variation of the human olfactory receptor gene family.
Am J Hum Genet
2008
17382427
V2R gene families degenerated in primates, dog and cow, but expanded in opossum.
Trends Genet
2007
17849013
Degeneration of the olfactory guanylyl cyclase D gene during primate evolution.
PLoS One
2007
15653832
Divergent V1R repertoires in five species: Amplification in rodents, decimation in primates, and a surprisingly small repertoire in dogs.
Genome Res
2005
16136133
Human subtelomeres are hot spots of interchromosomal recombination and segmental duplication.
Nature
2005
16269360
Olfaction: diverse species, conserved principles.
Neuron
2005
15057822
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Nature
2004
15273396
Large-scale copy number polymorphism in the human genome.
Science
2004
15060001
Species specificity in rodent pheromone receptor repertoires.
Genome Res
2004
14611657
Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.
Genome Biol
2003
11944992
Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.
Genomics
2002
12015274
The sense of smell: genomics of vertebrate odorant receptors.
Hum Mol Genet
2002
11875048
Different evolutionary processes shaped the mouse and human olfactory receptor gene families.
Hum Mol Genet
2002
11416212
Genomic analysis of orthologous mouse and human olfactory receptor loci.
Proc Natl Acad Sci U S A
2001
10449764
Sequence-tagged connectors: a sequence approach to mapping and scanning the human genome.
Proc Natl Acad Sci U S A
1999
1 - 50 of 50
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