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Author Details

Carla J Greenbaum
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
1977
225
63
PMIDPaper TitleJournal TitlePublished Year
36227635Risk Modeling to Reduce Monitoring of an Autoantibody-Positive Population to Prevent DKA at Type 1 Diabetes Diagnosis.J Clin Endocrinol Metab2023
37758901Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes.Commun Biol2023
37751304Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes.JCI Insight2023
37708415Hydroxychloroquine in Stage 1 Type 1 Diabetes.Diabetes Care2023
37520758ABCC8-Related Monogenic Diabetes Presenting Like Type 1 Diabetes in an Adolescent.AACE Clin Case Rep2023
37940642A standardized metric to enhance clinical trial design and outcome interpretation in type 1 diabetes.Nat Commun2023
38096190Testing a new platform to screen disease-modifying therapy in type 1 diabetes.PLoS One2023
37572381OGTT Metrics Surpass Continuous Glucose Monitoring Data for T1D Prediction in Multiple-Autoantibody-Positive Individuals.J Clin Endocrinol Metab2023
37202589Approval of teplizumab: implications for patients.Nat Rev Endocrinol2023
36920087Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial.Diabetes Care2023
36730530CGM Metrics Identify Dysglycemic States in Participants From the TrialNet Pathway to Prevention Study.Diabetes Care2023
36703975Characterizing T cell responses to enzymatically modified beta cell neo-epitopes.Front Immunol2023
35020411Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.Sci Transl Med2022
35840705From the prodromal stage of multiple sclerosis to disease prevention.Nat Rev Neurol2022
35388005Citrullination of glucokinase is linked to autoimmune diabetes.Nat Commun2022
35911690IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation.Front Immunol2022
36206465Recruitment and Retention Strategies for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium.Pancreas2022
36206461Assessing the Pathophysiology of Hyperglycemia in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium.Pancreas2022
36206460Rationale and Design for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: A Prospective Cohort Study From the Type 1 Diabetes in Acute Pancreatitis Consortium.Pancreas2022
36282595IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function.JCI Insight2022
35316839Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective.Diabetes2022
35041021Characterising the age-dependent effects of risk factors on type 1 diabetes progression.Diabetologia2022
34747368IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.JCI Insight2021
33881515Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies: Beyond a Simple Count.Endocr Rev2021
33741606Uncovering Pathways to Personalized Therapies in Type 1 Diabetes.Diabetes2021
33931405A Key to T1D Prevention: Screening and Monitoring Relatives as Part of Clinical Care.Diabetes2021
33658358Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals.Sci Transl Med2021
33550589Pancreatic islet reserve in type 1 diabetes.Ann N Y Acad Sci2021
34806648Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.JCI Insight2021
31597668High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes.Diabetes Care2020
31815738Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.J Clin Invest2020
31907557Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates.Diabetologia2020
31843946Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC.Diabetes Care2020
32019856Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody-Positive Individuals.Diabetes Care2020
31895699High residual C-peptide likely contributes to glycemic control in type 1 diabetes.J Clin Invest2020
33186361Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR.PLoS One2020
32573495Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells.JCI Insight2020
32995692Acute Hyperinsulinemia Alters Bone Turnover in Women and Men With Type 1 Diabetes.JBMR Plus2020
32789003Insulin is necessary but not sufficient: changing the therapeutic paradigm in type 1 diabetes.F1000Res2020
32669415Response to Comment on So et al. Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody-Positive Individuals. Diabetes Care 2020;43:913-917.Diabetes Care2020
32132004Erratum. Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention. Diabetes Care 2019;42:2228-2236.Diabetes Care2020
32457058C-Peptide Levels in Subjects Followed Longitudinally Before and After Type 1 Diabetes Diagnosis in TrialNet.Diabetes Care2020
32291282Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB1*04:01.Diabetes2020
31557315In-vivo assessment of T cell kinetics in individuals at risk for type 1 diabetes.Clin Exp Immunol2020
30530850Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.Diabetes Care2019
29925930Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes.Genes Immun2019
31442418Abnormalities in proinsulin processing in islets from individuals with longstanding T1D.Transl Res2019
31558546Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention.Diabetes Care2019
31457096Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes.Sci Adv2019
31572352Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study.Front Immunol2019
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Collaborators

Cate Speake
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 41
Jeffrey P Krischer
Health Informatics Institute, University of South Florida
Co-authored papers 38
Kevan C Herold
Yale University
Co-authored papers 28
Jane H Buckner
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 21
William W Kwok
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 19
Gerald T Nepom
Wash Benaroya Research Institute at Virginia Mason
Co-authored papers 19
Sarah Alice Long
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 17
Catherine Pihoker
Co-authored papers 14
Karen Cerosaletti
Center for Translational Immunology
Co-authored papers 13
Craig A Beam
Homer Stryker MD School of Medicine, Western Michigan University
Co-authored papers 13
Vivian H Gersuk
Center for Systems Immunology, Benaroya Research Institute
Co-authored papers 10
Peter S Linsley
8Benaroya Research Institute
Co-authored papers 10
Henry Rodriguez
Office of Cancer Clinical Proteomics Research, National Cancer Institute
Co-authored papers 10
Junbao Yang
Benaroya Research Institute
Co-authored papers 8
Colin O'Rourke
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 6
Michael R Rickels
Hospital of the University of Pennsylvania
Co-authored papers 6
Matthew J Dufort
Center for Systems Immunology, Benaroya Research Institute Seattle
Co-authored papers 6
Santica M Marcovina
Co-authored papers 6
Elisavet Serti
The Henry Jackson Foundation.
Co-authored papers 5
Mario G Rosasco
Center for Systems Immunology, Benaroya Research Institute
Co-authored papers 4
Mark S Anderson
Diabetes Center, University of California san francisco
Co-authored papers 4
Lawrence M Dolan
Co-authored papers 4
Elizabeth J Mayer-Davis
Co-authored papers 4
Mario R Ehlers
Clinical Trials Group
Co-authored papers 4
Giuseppina Imperatore
Co-authored papers 3
Dana Dabelea
Co-authored papers 3
Helena Reijonen
City of Hope Medical Center, Beckman Research Institute
Co-authored papers 3
Steven M Willi
Children's Hospital of Philadelphia
Co-authored papers 3
Noha Lim
Co-authored papers 3
Stephen S Rich
Co-authored papers 3
Release 1.2