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TKG
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Author Details
Full Name
Kim J Hasenkrug
Affiliation
National Institute of Allergy and Infectious Diseases
ORCID
Career Start Year
1986
Papers
124
H Index
39
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36434839
Practical Mouse Model to Investigate Therapeutics for Staphylococcusaureus Contaminated Surgical Mesh Implants.
J Surg Res
2023
37427590
Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected mice.
JCI Insight
2023
34923028
CD47 expression attenuates Ebola virus-induced immunopathology in mice.
Antiviral Res
2022
35404959
Detailed analysis of antibody responses to SARS-CoV-2 vaccination and infection in macaques.
PLoS Pathog
2022
36073812
CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir.
mBio
2022
35867811
Interferon resistance of emerging SARS-CoV-2 variants.
Proc Natl Acad Sci U S A
2022
35236754
CD47 Blockade Leads to Chemokine-Dependent Monocyte Infiltration and Loss of B Cells from the Splenic Marginal Zone.
J Immunol
2022
32598936
B-Cell Control of Regulatory T Cells in Friend Virus Infection.
J Mol Biol
2021
33572859
T-Cells and Interferon Gamma Are Necessary for Survival Following Crimean-Congo Hemorrhagic Fever Virus Infection in Mice.
Microorganisms
2021
33821272
Recovery from acute SARS-CoV-2 infection and development of anamnestic immune responses in T cell-depleted rhesus macaques.
bioRxiv
2021
34909774
Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection.
bioRxiv
2021
34311582
Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques.
mBio
2021
32294445
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell Rep
2020
33064743
Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis.
PLoS Pathog
2020
32576678
Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition.
mBio
2020
30670616
Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells.
mBio
2019
31792317
Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir.
Sci Rep
2019
31341068
Different Biological Activities of Specific Interferon Alpha Subtypes.
mSphere
2019
30770827
A functional subset of CD8[+] T cells during chronic exhaustion is defined by SIRPα expression.
Nat Commun
2019
31087035
Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity.
FEMS Microbiol Rev
2019
29112072
An advanced BLT-humanized mouse model for extended HIV-1 cure studies.
AIDS
2018
30085162
Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice.
J Infect Dis
2018
29447279
Regulatory T cells in retroviral infections.
PLoS Pathog
2018
29614127
Regulatory T cells suppress virus-specific antibody responses to Friend retrovirus infection.
PLoS One
2018
29605684
Mouse APOBEC3 expression in NIH 3T3 cells mediates hypermutation of AKV murine leukemia virus.
Virology
2018
28765225
B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection.
mBio
2017
28415995
Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction.
Retrovirology
2017
28330900
Adaptive Immune Responses to Zika Virus Are Important for Controlling Virus Infection and Preventing Infection in Brain and Testes.
J Immunol
2017
28798348
Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.
Sci Rep
2017
27099312
Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo.
J Virol
2016
26670361
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.
AIDS Res Hum Retroviruses
2016
26609939
No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts.
Virology
2016
27601621
Ebola Virus Replication and Disease Without Immunopathology in Mice Expressing Transgenes to Support Human Myeloid and Lymphoid Cell Engraftment.
J Infect Dis
2016
26846717
Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.
Sci Rep
2016
25392466
Serial infection of diverse host (Mus) genotypes rapidly impedes pathogen fitness and virulence.
Proc Biol Sci
2015
26463758
Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulation.
Sci Rep
2015
26529416
Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms.
PLoS Pathog
2015
26670699
Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2.
PLoS One
2015
24707025
CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice.
J Virol
2014
25000983
Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.
J Immunol
2014
25098294
Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.
J Immunol
2014
24769067
Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2(-/-)γc(-/-)CD47(-/-) background.
J Immunol Methods
2014
24821801
Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.
Proc Natl Acad Sci U S A
2014
24872193
Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.
J Immunol
2014
24889233
Mice of the resistant H-2(b) haplotype mount broad CD4(+) T cell responses against 9 distinct Friend virus epitopes.
Virology
2014
23315078
IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.
J Immunol
2013
24021673
BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection.
Blood
2013
23645880
IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection.
J Immunol
2013
23698707
Experimental viral evolution reveals major histocompatibility complex polymorphisms as the primary host factors controlling pathogen adaptation and virulence.
Genes Immun
2013
23536666
CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells.
J Virol
2013
1 - 50 of 124
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Co-authored papers
3
Erik Van Dis
University of California berkeley
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Marek Widera
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Co-authored papers
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Mark M Davis
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Shimon Sakaguchi
Institute for Frontier Medical Sciences, Kyoto University
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Mary E Moreno
San Francisco General Hospital, University of California
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Frederick National Laboratory
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