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Author Details

Kim J Hasenkrug
National Institute of Allergy and Infectious Diseases
1986
124
39
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36434839Practical Mouse Model to Investigate Therapeutics for Staphylococcusaureus Contaminated Surgical Mesh Implants.J Surg Res2023
37427590Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected mice.JCI Insight2023
34923028CD47 expression attenuates Ebola virus-induced immunopathology in mice.Antiviral Res2022
35404959Detailed analysis of antibody responses to SARS-CoV-2 vaccination and infection in macaques.PLoS Pathog2022
36073812CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir.mBio2022
35867811Interferon resistance of emerging SARS-CoV-2 variants.Proc Natl Acad Sci U S A2022
35236754CD47 Blockade Leads to Chemokine-Dependent Monocyte Infiltration and Loss of B Cells from the Splenic Marginal Zone.J Immunol2022
32598936B-Cell Control of Regulatory T Cells in Friend Virus Infection.J Mol Biol2021
33572859T-Cells and Interferon Gamma Are Necessary for Survival Following Crimean-Congo Hemorrhagic Fever Virus Infection in Mice.Microorganisms2021
33821272Recovery from acute SARS-CoV-2 infection and development of anamnestic immune responses in T cell-depleted rhesus macaques.bioRxiv2021
34909774Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection.bioRxiv2021
34311582Recovery from Acute SARS-CoV-2 Infection and Development of Anamnestic Immune Responses in T Cell-Depleted Rhesus Macaques.mBio2021
32294445Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.Cell Rep2020
33064743Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis.PLoS Pathog2020
32576678Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition.mBio2020
30670616Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells.mBio2019
31792317Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir.Sci Rep2019
31341068Different Biological Activities of Specific Interferon Alpha Subtypes.mSphere2019
30770827A functional subset of CD8[+] T cells during chronic exhaustion is defined by SIRPα expression.Nat Commun2019
31087035Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity.FEMS Microbiol Rev2019
29112072An advanced BLT-humanized mouse model for extended HIV-1 cure studies.AIDS2018
30085162Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice.J Infect Dis2018
29447279Regulatory T cells in retroviral infections.PLoS Pathog2018
29614127Regulatory T cells suppress virus-specific antibody responses to Friend retrovirus infection.PLoS One2018
29605684Mouse APOBEC3 expression in NIH 3T3 cells mediates hypermutation of AKV murine leukemia virus.Virology2018
28765225B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection.mBio2017
28415995Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction.Retrovirology2017
28330900Adaptive Immune Responses to Zika Virus Are Important for Controlling Virus Infection and Preventing Infection in Brain and Testes.J Immunol2017
28798348Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.Sci Rep2017
27099312Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo.J Virol2016
26670361Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.AIDS Res Hum Retroviruses2016
26609939No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts.Virology2016
27601621Ebola Virus Replication and Disease Without Immunopathology in Mice Expressing Transgenes to Support Human Myeloid and Lymphoid Cell Engraftment.J Infect Dis2016
26846717Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.Sci Rep2016
25392466Serial infection of diverse host (Mus) genotypes rapidly impedes pathogen fitness and virulence.Proc Biol Sci2015
26463758Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulation.Sci Rep2015
26529416Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms.PLoS Pathog2015
26670699Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2.PLoS One2015
24707025CD8+ T cells are essential for controlling acute friend retrovirus infection in C57BL/6 mice.J Virol2014
25000983Clonotypic composition of the CD4+ T cell response to a vectored retroviral antigen is determined by its speed.J Immunol2014
25098294Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.J Immunol2014
24769067Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2(-/-)γc(-/-)CD47(-/-) background.J Immunol Methods2014
24821801Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.Proc Natl Acad Sci U S A2014
24872193Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.J Immunol2014
24889233Mice of the resistant H-2(b) haplotype mount broad CD4(+) T cell responses against 9 distinct Friend virus epitopes.Virology2014
23315078IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.J Immunol2013
24021673BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection.Blood2013
23645880IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection.J Immunol2013
23698707Experimental viral evolution reveals major histocompatibility complex polymorphisms as the primary host factors controlling pathogen adaptation and virulence.Genes Immun2013
23536666CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cells.J Virol2013
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Collaborators

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Co-authored papers 46
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Co-authored papers 41
Co-authored papers 19
National Institute of Allergy and Infectious Diseases
Co-authored papers 9
Gladstone Institute of Virology, USA University of California san francisco
Co-authored papers 5
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Co-authored papers 4
Gladstone Institutes
Co-authored papers 3
National Institutes of Allergy and Infectious Disease, National Institutes of Health
Co-authored papers 3
University of California berkeley
Co-authored papers 3
Goethe University Frankfurt, University Hospital, Institute for Medical Virology
Co-authored papers 3
Co-authored papers 2
Institute for Frontier Medical Sciences, Kyoto University
Co-authored papers 2
San Francisco General Hospital, University of California
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Stanford University
Co-authored papers 1
Frederick National Laboratory
Co-authored papers 1
Northwestern University Feinberg School of Medicine
Co-authored papers 1
Co-authored papers 1
Mayo Clinic
Co-authored papers 1
University of California, USA Gladstone Institutes san francisco
Co-authored papers 1
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J. David Gladstone Institutesgrid.249878.8
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National Institute of Allergy and Infectious Diseases
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Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
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Co-authored papers 1
University of Colorado School of Medicine
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