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Author Details

Huck-Hui Ng
1996
127
66
PMIDPaper TitleJournal TitlePublished Year
37339952Selective binding of retrotransposons by ZFP352 facilitates the timely dissolution of totipotency network.2023
35776115SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates.Nucleic Acids Res2022
36001968Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency.Cell Reports2022
36200589Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease.EMBO Reports2022
35403791Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease.EMBO Reports2022
34437143The making of an ovarian niche.Science2021
34288055Lewy Body-like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α-Synuclein Mutations.Annals of Neurology2021
34341842Emerging liver organoid platforms and technologies.Cell Regeneration2021
32553762Human Pluripotent Stem Cell-Derived Organoids as Models of Liver Disease.Gastroenterology2020
32083763Generation of homogeneous midbrain organoids with in vivo-like cellular composition facilitates neurotoxin-based Parkinson's disease modeling.Stem Cells2020
31446059New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation.Gastroenterology2019
31857479Potassium channel dysfunction in human neuronal models of Angelman syndrome.Science2019
35026914A Chemically Well-Defined, Self-Assembling 3D Substrate for Long-Term Culture of Human Pluripotent Stem Cells.ACS Applied Bio Materials2019
31522976Lgr5 and Col22a1 Mark Progenitor Cells in the Lineage toward Juvenile Articular Chondrocytes.Stem Cell Reports2019
31522974A Chemically Defined Feeder-free System for the Establishment and Maintenance of the Human Naive Pluripotent State.Stem Cell Reports2019
29468184Translational potential of human brain organoids.Annals of Clinical and Translational Neurology2018
28314766The metabolic programming of stem cells.Genes and Development2017
28855732Lab-grown mini-brains upgraded.Nature Cell Biology2017
28368037High-resolution RNA allelotyping along the inactive X chromosome: evidence of RNA polymerase III in regulating chromatin configuration.Sci Rep2017
29214996The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation.Sci Rep2017
27498872Direct Induction and Functional Maturation of Forebrain GABAergic Neurons from Human Pluripotent Stem Cells.Cell Reports2016
27152435Looping around Reprogramming: The Topological Memory of Induced Pluripotency.2016
26833176Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challenges.Journal of Neurology, Neurosurgery and Psychiatry2016
26957309Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters.Genome Res2016
27402545CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome.EMBO Reports2016
27476966Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons.Cell Stem Cell2016
25053715Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.Gut2015
32262581Layered polymeric capsules inhibiting the activity of RNases for intracellular delivery of messenger RNA.Journal of Materials Chemistry B2015
25658370Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells.2015
26232226Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways.Cell2015
26582790Biological Networks Governing the Acquisition, Maintenance, and Dissolution of Pluripotency: Insights from Functional Genomics Approaches.Cold Spring Harbor Symposia on Quantitative Biology2015
245574722013 Runme Shaw memorial lecture: clinical applications of stem cells in modern medicine--21st century and beyond.Annals of the Academy of Medicine, Singapore2014
24681886The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity.Nat Struct Mol Biol2014
24905170Klf2 is an essential factor that sustains ground state pluripotency.2014
25026204Sox2: masterminding the root of cancer.Cancer Cell2014
24702994Identifiability and privacy in pluripotent stem cell research.Cell Stem Cell2014
24789761The role of SON in splicing, development, and disease.Wiley interdisciplinary reviews. RNA2014
25008978Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.Nature Communications2014
24648406Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.Stem Cells2014
23727019Genome-wide kinase-chromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells.Molecular Cell2013
24315441Induction of a human pluripotent state with distinct regulatory circuitry that resembles preimplantation epiblast.2013
23770639Uniform, optimal signal processing of mapped deep-sequencing data.Nat Biotechnol2013
24013217SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells.Nat Cell Biol2013
23788624A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo.Genes Dev2013
24004469The mystique of cellular reprogramming.Current Opinion in Genetics and Development2013
23916717Driving pluripotency and reprogramming: nuclear receptors at the helm.Seminars in Cell and Developmental Biology2013
23280602A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming.Stem Cells2013
23642364Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.2013
23352811In vivo epigenomic profiling of germ cells reveals germ cell molecular signatures.Dev Cell2013
23229513The transcriptional regulation of pluripotency.Cell Research2013
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Peking-Tsinghua Center for Life Sciences, College of Life Sciences, Peking University
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HHMI/NYU Langone School of Medicine
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