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Author Details
Full Name
James E Longbotham
Affiliation
University of California San Francisco
ORCID
Career Start Year
2015
Papers
11
H Index
7
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
33621062
Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A.
ACS Chem Biol
2023
35839775
Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.
Cell Rep
2022
33314922
Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3.
ACS Chem Biol
2021
34816261
Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2.
bioRxiv
2021
32475402
Dissecting contributions of catalytic and reader domains in regulation of histone demethylation.
Methods Enzymol
2020
31985200
Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A.
Biochemistry
2020
32758979
Domain cross-talk in regulation of histone modifications: Molecular mechanisms and targeting opportunities.
Curr Opin Chem Biol
2020
30626866
Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling.
Nat Commun
2019
31157122
Convergence of theory and experiment on the role of preorganization, quantum tunneling and enzyme motions into flavoenzyme-catalyzed hydride transfer.
ACS Catal
2019
27676389
Untangling Heavy Protein and Cofactor Isotope Effects on Enzyme-Catalyzed Hydride Transfer.
J Am Chem Soc
2016
26368022
Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase.
Biochemistry
2015
1 - 11 of 11
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Jennifer M Hayashi
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Co-authored papers
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Erron W Titus
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Co-authored papers
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Northwestern University
Co-authored papers
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University of California San Francisco
Co-authored papers
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Gladstone Institutes
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