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Author Details
Full Name
Stephan A M??ller
Affiliation
German Center for Neurodegenerative Diseases, Technical University of Munich
ORCID
Career Start Year
2010
Papers
52
H Index
19
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36745974
A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases.
EBioMedicine
2023
37596282
Reactivated endogenous retroviruses promote protein aggregate spreading.
Nat Commun
2023
37388246
Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics.
Front Mol Biosci
2023
37430025
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.
Nat Metab
2023
36810097
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130.
Mol Neurodegener
2023
34958451
The β-Secretase Substrate Seizure 6-Like Protein (SEZ6L) Controls Motor Functions in Mice.
Mol Neurobiol
2022
35736286
Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State.
Membranes (Basel)
2022
35666874
Signatures of glial activity can be detected in the CSF proteome.
Proc Natl Acad Sci U S A
2022
35688487
LncRNA <i>RUS</i> shapes the gene expression program towards neurogenesis.
Life Sci Alliance
2022
36443293
Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae.
Nat Commun
2022
36611872
Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.
Cells
2022
36470941
Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
Sci Rep
2022
36563667
Spatial proteomics in three-dimensional intact specimens.
Cell
2022
35074002
Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates.
Acta Neuropathol Commun
2022
32951307
Neuronal Differentiation of LUHMES Cells Induces Substantial Changes of the Proteome.
Proteomics
2021
33627648
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
Nat Commun
2021
33785583
ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage.
J Am Soc Nephrol
2021
33673623
Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates.
Int J Mol Sci
2021
34706241
Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery.
Cell Rep
2021
34380771
The <i>Uppsala APP</i> deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.
Sci Transl Med
2021
34613632
The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system.
FASEB J
2021
34667166
Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions.
Nat Commun
2021
32195080
Fibroblast Growth Factor 2-Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons.
Adv Sci (Weinh)
2020
31908000
Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
FASEB J
2020
32078678
Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis.
J Exp Med
2020
33101391
FGF2 Affects Parkinson's Disease-Associated Molecular Networks Through Exosomal Rab8b/Rab31.
Front Genet
2020
32707433
Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons.
iScience
2020
32954517
An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
EMBO J
2020
32567721
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.
EMBO J
2020
30617257
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Nat Neurosci
2019
31501572
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Nat Neurosci
2019
31266883
Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells.
Life Sci Alliance
2019
30833305
NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease.
EMBO Mol Med
2019
31061204
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
EMBO Rep
2019
30733281
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
EMBO Rep
2019
30733280
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
EMBO Rep
2019
29716987
Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.
Mol Cell Proteomics
2018
30279425
Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor.
Sci Rep
2018
29725820
CADASIL brain vessels show a HTRA1 loss-of-function profile.
Acta Neuropathol
2018
29414760
Proteome Data Improves Protein Function Prediction in the Interactome of <i>Helicobacter pylori</i>.
Mol Cell Proteomics
2018
27476612
Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue.
Matrix Biol
2017
27991726
An optimised version of the secretome protein enrichment with click sugars (SPECS) method leads to enhanced coverage of the secretome.
Proteomics
2017
27716410
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
Mol Neurodegener
2016
27790089
Proteomic Substrate Identification for Membrane Proteases in the Brain.
Front Mol Neurosci
2016
25348772
Integration of conventional quantitative and phospho-proteomics reveals new elements in activated Jurkat T-cell receptor pathway maintenance.
Proteomics
2015
26553928
Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells.
J Cell Biol
2015
26139848
Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo.
Mol Cell Proteomics
2015
25979772
Stable isotope labeling by amino acids in cell culture based proteomics reveals differences in protein abundances between spiral and coccoid forms of the gastric pathogen Helicobacter pylori.
J Proteomics
2015
23665149
Identification of new protein coding sequences and signal peptidase cleavage sites of Helicobacter pylori strain 26695 by proteogenomics.
J Proteomics
2013
22990618
Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix.
J Mater Sci Mater Med
2012
1 - 50 of 52
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2
Peter Uetz
Center for the Study of Biological Complexity, Virginia Commonwealth University
Co-authored papers
2
Ivo L Hofacker
Co-authored papers
2
Christian Haass
German Center for Neurodegenerative Diseases (DZNE) Munich
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2
Gunnar F Schr??der
Institute of Biological Information Processing (Structural Biochemistry)
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1
Thomas Korn
TUM School of Medicine, Technical University of Munich
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1
An Chi
Co-authored papers
1
Ronald Naumann
Co-authored papers
1
Peter Jedlicka
Justus Liebig University Giessen
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1
John Harry Caufield
American Heart Association, American Society for Microbiology, International Society for Computational Biology, Lawrence Berkeley National Laboratory, University of California Los Angeles, University of Delaware, Virginia Commonwealth University
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1
Allan I Levey
Emory University School of Medicine
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Manolis Kellis
Massachusetts Institute of Technology
Co-authored papers
1
Martin Ingelsson
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1
Lars Lannfelt
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Chio Oka
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