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Author Details

David B Kastrinsky
2003
17
12
PMIDPaper TitleJournal TitlePublished Year
32954276Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma.Brain Commun2020
29358171Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer.Cancer Res2018
28504649Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.J Clin Invest2017
26703475Identifying a Small Molecule Blocking Antigen Presentation in Autoimmune Thyroiditis.J Biol Chem2016
26507691All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.FEBS J2016
28290285Corrigendum to "Reengineered tricyclic anti-cancer agents" [Bioorg. Med. Chem. 23 (2015) 6528-6534].Bioorg Med Chem2015
26372073Reengineered tricyclic anti-cancer agents.Bioorg Med Chem2015
22252828SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.Antimicrob Agents Chemother2012
20161438Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases.Tetrahedron Letters2010
20381346Synthesis and evaluation of a series of C5'-substituted duocarmycin SA analogs.Bioorganic and Medicinal Chemistry Letters2010
17147378Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer.Journal of the American Chemical Society2006
15049620Effective asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI).Journal of Organic Chemistry2004
15237994Total synthesis, structure revision, and absolute configuration of (+)-yatakemycin.Journal of the American Chemical Society2004
12952479DNA alkylation properties of yatakemycin.Journal of the American Chemical Society2003
12841785Synthesis and X-ray analysis of an unprecedented and stable 2-aza-4,4-spirocyclopropacyclohexadienone.Organic Letters2003
12901927Establishment of substituent effects in the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.Bioorganic and Medicinal Chemistry2003
14604371Synthesis and evaluation of duocarmycin and CC-1065 analogues incorporating the 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]-3-azaindol-4-one (CBA) alkylation subunit.Journal of Organic Chemistry2003
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