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Author Details

Nicholas J Schork
University of California San Diego
1987
534
108
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37205553Exploring the genetic heterogeneity of Alzheimer's disease: Evidence for genetic subtypes.medRxiv2024
36335489Interrogating the Human Diplome: Computational Methods, Emerging Applications, and Challenges.Methods Mol Biol2023
37492100The human pangenome reference anticipates equitable and fundamental genomic insights.Cell Genom2023
37960259Pentadecanoic Acid (C15:0), an Essential Fatty Acid, Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds.Nutrients2023
38012377Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers.Commun Biol2023
37661888Pathway-Specific Polygenic Risk Scores Correlate with Clinical Status and Alzheimer's Disease-Related Biomarkers.J Alzheimers Dis2023
37481675Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers.Commun Biol2023
35560106Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children.Hepatology2023
37323571A CRISPR-enhanced metagenomic NGS test to improve pandemic preparedness.Cell Rep Methods2023
37255593Exploring human biology with N-of-1 clinical trials.Camb Prism Precis Med2023
37408271Genetic and Protein Network Underlying the Convergence of Rett-Syndrome-like (RTT-L) Phenotype in Neurodevelopmental Disorders.Cells2023
37269831Distinct longevity mechanisms across and within species and their association with aging.Cell2023
37398146Borrelia PeptideAtlas: A proteome resource of common <i>Borrelia burgdorferi</i> isolates for Lyme research.bioRxiv2023
36909609Pathway-specific polygenic risk scores correlate with clinical status and Alzheimer's-related biomarkers.Res Sq2023
36802395A time-series analysis of blood-based biomarkers within a 25-year longitudinal dolphin cohort.PLoS Comput Biol2023
35119614Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring.Geroscience2022
35580607Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation.Cell Metab2022
35603292Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test.Commun Med (Lond)2022
35466328Does Modulation of an Epigenetic Clock Define a Geroprotector?Adv Geriatr Med Res2022
37032736Accommodating Serial Correlation and Sequential Design Elements in Personalized Studies and Aggregated Personalized Studies.Harv Data Sci Rev2022
36613555A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.Int J Mol Sci2022
35874687A mRNA Vaccine Encoding for a RBD 60-mer Nanoparticle Elicits Neutralizing Antibodies and Protective Immunity Against the SARS-CoV-2 Delta Variant in Transgenic K18-hACE2 Mice.Front Immunol2022
36389222Assessing brain and biological aging trajectories associated with Alzheimer's disease.Front Neurosci2022
36012560Hepatic PEMT Expression Decreases with Increasing NAFLD Severity.Int J Mol Sci2022
35128293Psychometric Properties of a New Stress-Related Personality Scale: The Virtual Inventory of Behavior and Emotions (VIBE).Chronic Stress (Thousand Oaks)2022
32789669Impacts of personal DNA ancestry testing.J Community Genet2021
33826614Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial.PLoS One2021
33650986Characterizing Emotional State Transitions During Prolonged Use of a Mindfulness and Meditation App: Observational Study.JMIR Ment Health2021
33833060Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.Proc Natl Acad Sci U S A2021
34512728Cross-Species and Human Inter-Tissue Network Analysis of Genes Implicated in Longevity and Aging Reveal Strong Support for Nutrient Sensing.Front Genet2021
34210964Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance.NPJ Aging Mech Dis2021
34197020Genetic signature of human longevity in PKC and NF-κB signaling.Aging Cell2021
34255702Correction: Association Between Improvement in Baseline Mood and Long-Term Use of a Mindfulness and Meditation App: Observational Study.JMIR Ment Health2021
32064741Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.Addict Biol2021
32127543Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons.Nat Commun2020
34713026Optimizing Aggregated N-Of-1 Trial Designs for Predictive Biomarker Validation: Statistical Methods and Theoretical Findings.Front Digit Health2020
31863816Circulating tumor DNA as an early cancer detection tool.Pharmacol Ther2020
33239366Conserved Genomic Terminals of SARS-CoV-2 as Coevolving Functional Elements and Potential Therapeutic Targets.mSphere2020
33068417signatureSearch: environment for gene expression signature searching and functional interpretation.Nucleic Acids Res2020
32778591A 25-y longitudinal dolphin cohort supports that long-lived individuals in same environment exhibit variation in aging rates.Proc Natl Acad Sci U S A2020
32676601Conserved Genomic Terminals of SARS-CoV-2 as Co-evolving Functional Elements and Potential Therapeutic Targets.bioRxiv2020
32535886Strategies for Testing Intervention Matching Schemes in Cancer.Clin Pharmacol Ther2020
30636025An investigation of indirect effects of personality features on anorexia nervosa severity through interoceptive dysfunction in individuals with lifetime anorexia nervosa diagnoses.Int J Eat Disord2019
31724058Genetic Support for Longevity-Enhancing Drug Targets: Issues, Preliminary Data, and Future Directions.J Gerontol A Biol Sci Med Sci2019
31724055Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals.J Gerontol A Biol Sci Med Sci2019
31269712Power and Design Issues in Crossover-Based N-Of-1 Clinical Trials with Fixed Data Collection Periods.Healthcare (Basel)2019
31209850Artificial Intelligence and Personalized Medicine.Cancer Treat Res2019
31372505Artificial intelligence and machine learning in clinical development: a translational perspective.NPJ Digit Med2019
31484056Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease.Cell Metab2019
30923642Combinatorial interactions of genetic variants in human cardiomyopathy.Nat Biomed Eng2019
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Collaborators

Cinnamon Bloss
University of California
Co-authored papers 49
Daniel T O'Connor
Institute for Genomic Medicine, University of California San Diego
Co-authored papers 45
Sarah S Murray
University of California San Diego Health System
Co-authored papers 37
Eric J Topol
Universidade Federal de Sao Paulo
Co-authored papers 36
Caroline M Nievergelt
VA San Diego Healthcare System (VASDHS)
Co-authored papers 36
Ondrej Libiger
The Qualcomm Institute, University of California
Co-authored papers 35
Ali Torkamani
Scripps Science Institute
Co-authored papers 35
Tiffany A Greenwood
University of California San Diego
Co-authored papers 34
Erin N Smith
Department of Pediatrics and Rady's Children's Hospital, University of California
Co-authored papers 27
Sushil K Mahata
Co-authored papers 23
Gerald S Berenson
LSU Health New Orleans Medical Center
Co-authored papers 23
Wei Chen
School of Public Health and Tropical Medicine, Tulane University
Co-authored papers 22
Wade H Berrettini
University of Pennsylvania
Co-authored papers 22
Jennifer Wessel
Co-authored papers 21
Rany M Salem
Co-authored papers 21
Michael G Ziegler
University of California San Diego School of Medicine
Co-authored papers 21
Brinda K Rana
University of California
Co-authored papers 21
Sathanur R Srinivasan
School of Public Health and Tropical Medicine, Tulane University
Co-authored papers 19
John R Kelsoe
University of California
Co-authored papers 19
Anders M Dale
University of California San Diego
Co-authored papers 17
Ming T Tsuang
University of California San Diego
Co-authored papers 15
John I Nurnberger
Stark Neurosciences Research Institute, Indiana University School of Medicine
Co-authored papers 15
Gen Wen
Co-authored papers 14
Laurent Taupenot
VA San Diego Healthcare System, University of California at San Diego
Co-authored papers 13
David W Craig
University of Southern California
Co-authored papers 13
Tatiana Foroud
Indiana University School of Medicine
Co-authored papers 13
Burcu F Darst
Fred Hutchinson Cancer Center
Co-authored papers 13
John P Rice
Washington University School of Medicine
Co-authored papers 12
Daniel L Koller
Indiana University School of Medicine
Co-authored papers 12
Howard J Edenberg
Indiana University School of Medicine
Co-authored papers 12
Release 1.2