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Author Details

Robert Sladek
1997
117
54
PMIDPaper TitleJournal TitlePublished Year
37546893Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus.medRxiv2023
36191509Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid-Induced Rat β-Cell Proliferation.2023
37790568Heterogeneous effects on type 2 diabetes and cardiovascular outcomes of genetic variants and traits associated with fasting insulin.Res Sq2023
36528348Predicting the response to GLP-1 receptor agonists: an unexpected role for β-arrestin-1.2023
35272070Glycerol-3-phosphate phosphatase operates a glycerol shunt in pancreatic β-cells that controls insulin secretion and metabolic stress.Mol Metab2022
36198384Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia.Mol Metab2022
35787637Discriminating protein tags on a dsDNA construct using a Dual Nanopore Device.Scientific Reports2022
33893225Science fiction authors' perspectives on human genetic engineering.Med Humanit2022
34503867The Genetic Discrimination Observatory: confronting novel issues in genetic discrimination.Trends Genet2021
34108472Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.Nat Commun2021
33201419Correction to: Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants.Cell Mol Neurobiol2021
32902719Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population.Hum Genet2021
33010019Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants.Cell Mol Neurobiol2021
32754192A Long Non-coding RNA, <i>LOC157273</i>, Is an Effector Transcript at the Chromosome 8p23.1-<i>PPP1R3B</i> Metabolic Traits and Type 2 Diabetes Risk Locus.Front Genet2020
31063794Sex-specific effects of a microsatellite polymorphism on human growth hormone receptor gene expression.Molecular and Cellular Endocrinology2019
30066306Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms.Molecular Neurobiology2019
30683700-Dependent Immune and Central Nervous System Mechanisms Control Viral Replication and Inflammation during Mouse Herpes Simplex Encephalitis.Journal of Immunology2019
31118516Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.Nature2019
29316219Characterization of a FOXG1:TLE1 transcriptional network in glioblastoma-initiating cells.Molecular Oncology2018
29901692Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling.Endocrinology2018
29654238Transverse dielectrophoretic-based DNA nanoscale confinement.Scientific Reports2018
29503171The many faces of diabetes: addressing heterogeneity of a complex disease.Lancet Diabetes and Endocrinology,The2018
29279374Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.Proc Natl Acad Sci U S A2018
29632382Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.Nat Genet2018
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
29257133Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2017
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
28898252Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.PLoS Med2017
28696925Mouse Chromosome 4 Is Associated with the Baseline and Allergic IgE Phenotypes.G3: Genes, Genomes, Genetics2017
27980644Independent test assessment using the extreme value distribution theory.BMC Proc2016
27043434Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression.PLoS ONE2016
27398621The genetic architecture of type 2 diabetes.Nature2016
27604870Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection.Nucleic Acids Research2016
25189778BigDataScript: a scripting language for data pipelines.2015
26017687A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.Nat Commun2015
26551672Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Nat Genet2015
26062011Development of a platform for single cell genomics using convex lens-induced confinement.Lab on a Chip2015
25092333Convex lens-induced nanoscale templating.Proceedings of the National Academy of Sciences of the United States of America2014
24316981Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.Nat Genet2014
24951664Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.Circ Cardiovasc Genet2014
25210878Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals.Journal of Clinical Endocrinology and Metabolism2014
24514567A genome-wide association study of anorexia nervosa.Mol Psychiatry2014
25111050Mapping of a chromosome 12 region associated with airway hyperresponsiveness in a recombinant congenic mouse strain and selection of potential candidate genes by expression and sequence variation analyses.PLoS ONE2014
24686848Low copy number of the salivary amylase gene predisposes to obesity.Nat Genet2014
23554873Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity.PLoS One2013
23841706An electrochemically controlled microcantilever biosensor.Langmuir2013
22147266Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.Physiol Genomics2012
22479202Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.PLoS Genet2012
22299040Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture.PLoS ONE2012
22693455Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.PLoS Genet2012
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German Research Center for Cardiovascular Disease (DZHK)
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