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Author Details

William J Howat
Cancer Research UK Cambridge Institute
1994
49
27
PMIDPaper TitleJournal TitlePublished Year
33811746Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first-line platinum chemotherapy in high grade serous ovarian cancer.Cancer Med2021
33811746Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first-line platinum chemotherapy in high grade serous ovarian cancer.Cancer Med2021
32394372Guidelines for the Optimization and Validation of In Situ Hybridization.Methods Mol Biol2020
32394372Guidelines for the Optimization and Validation of In Situ Hybridization.Methods Mol Biol2020
31492872Proliferation Tumour Marker Network (PTM-NET) for the identification of tumour region in Ki67 stained breast cancer whole slide images.Sci Rep2019
31492872Proliferation Tumour Marker Network (PTM-NET) for the identification of tumour region in Ki67 stained breast cancer whole slide images.Sci Rep2019
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
30385821pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.Br J Cancer2018
29991697Harnessing citizen science through mobile phone technology to screen for immunohistochemical biomarkers in bladder cancer.Br J Cancer2018
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
29635390RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.Ann Oncol2018
29991697Harnessing citizen science through mobile phone technology to screen for immunohistochemical biomarkers in bladder cancer.Br J Cancer2018
30385821pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.Br J Cancer2018
29635390RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.Ann Oncol2018
27959886Crowdsourcing for translational research: analysis of biomarker expression using cancer microarrays.Br J Cancer2017
28945760Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.PLoS Genet2017
28209913Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I.J Nucl Med2017
27959886Crowdsourcing for translational research: analysis of biomarker expression using cancer microarrays.Br J Cancer2017
28209913Rapid Imaging of Tumor Cell Death In Vivo Using the C2A Domain of Synaptotagmin-I.J Nucl Med2017
28945760Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.PLoS Genet2017
26972697Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).Sci Rep2016
26972697Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).Sci Rep2016
26986977An Examination of the Association between FOXA1 Staining Level and Biochemical Recurrence following Salvage Radiation Therapy for Recurrent Prostate Cancer.PLoS One2016
27071814Detection of colorectal dysplasia using fluorescently labelled lectins.Sci Rep2016
26347531MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model.Gut2016
26679376Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers.Br J Cancer2016
27525720NOTCH1 mediates a switch between two distinct secretomes during senescence.Nat Cell Biol2016
26347531MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model.Gut2016
26679376Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers.Br J Cancer2016
27525720NOTCH1 mediates a switch between two distinct secretomes during senescence.Nat Cell Biol2016
27071814Detection of colorectal dysplasia using fluorescently labelled lectins.Sci Rep2016
26986977An Examination of the Association between FOXA1 Staining Level and Biochemical Recurrence following Salvage Radiation Therapy for Recurrent Prostate Cancer.PLoS One2016
25989187Use of Ex Vivo Normothermic Perfusion for Quality Assessment of Discarded Human Donor Pancreases.Am J Transplant2015
25989187Use of Ex Vivo Normothermic Perfusion for Quality Assessment of Discarded Human Donor Pancreases.Am J Transplant2015
26249175Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.Cancer Res2015
26288840Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer.EBioMedicine2015
26249175Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.Cancer Res2015
26288840Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer.EBioMedicine2015
24067278SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice.Gut2014
25606621Advancing the boundaries of molecular cellular pathology.Methods2014
27499890Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium.J Pathol Clin Res2014
24067278SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice.Gut2014
25033211Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues.PLoS One2014
24525140Antibody validation of immunohistochemistry for biomarker discovery: recommendations of a consortium of academic and pharmaceutical based histopathology researchers.Methods2014
24561827Tissue fixation and the effect of molecular fixatives on downstream staining procedures.Methods2014
24737870HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.EMBO Mol Med2014
27499890Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium.J Pathol Clin Res2014
25606621Advancing the boundaries of molecular cellular pathology.Methods2014
25033211Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues.PLoS One2014
24737870HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.EMBO Mol Med2014
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Collaborators

The Usher Institute, The University of Edinburgh
Co-authored papers 5
Center for Cancer Genetic Epidemiology, University of Cambridge
Co-authored papers 5
National Cancer Institute
Co-authored papers 5
University of Cambridge
Co-authored papers 5
Mayo Clinic
Co-authored papers 5
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 4
Mayo Clinic
Co-authored papers 4
Cambridge University Hospitals National Health Service Foundation Trust
Co-authored papers 4
Cancer Research UK Manchester Institute, University of Manchester
Co-authored papers 4
University of Oxford, John Radcliffe Hospital
Co-authored papers 4
University of Cambridge
Co-authored papers 4
Instituto de Salud Carlos III
Co-authored papers 3
Co-authored papers 3
Oncology R&D
Co-authored papers 3
University College London
Co-authored papers 3
University of St Andrews
Co-authored papers 3
Erasmus Medical Center
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
University College London
Co-authored papers 3
University College London
Co-authored papers 3
University College London
Co-authored papers 2
Wellcome Sanger Institute
Co-authored papers 2
University of Oxford
Co-authored papers 2
Wellcome Sanger Institute
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
The Royal Marsden NHS Foundation Trust
Co-authored papers 2
The Institute of Cancer Research
Co-authored papers 2
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 2
University of Oxford
Co-authored papers 2
Barts Cancer Institute, Queen Mary University of London
Co-authored papers 2