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Author Details

Swagata Ghatak
National Institute of Science Education and Research
2016
13
9
PMIDPaper TitleJournal TitlePublished Year
36175661Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection.Nat Chem Biol2023
36817649Aberrant protein S-nitrosylation contributes to hyperexcitability-induced synaptic damage in Alzheimer's disease: Mechanistic insights and potential therapies.Front Neural Circuits2023
35411336Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection.bioRxiv2022
32467645NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models.Mol Psychiatry2021
33483428α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss.J Neurosci2021
33692125S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.Proc Natl Acad Sci U S A2021
34360966Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases.Int J Mol Sci2021
32997602Novel Therapeutic Approach for Excitatory/Inhibitory Imbalance in Neurodevelopmental and Neurodegenerative Diseases.Annu Rev Pharmacol Toxicol2021
31782729Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls.Elife2019
30027906Parkinson's disease: what the model systems have taught us so far.J Genet2018
26843094Lactate modulates the intracellular pH sensitivity of human TREK1 channels.Pflugers Arch2016
27062641l-Lactate mediates neuroprotection against ischaemia by increasing TREK1 channel expression in rat hippocampal astrocytes in vitro.J Neurochem2016
26445100Ischaemic concentrations of lactate increase TREK1 channel activity by interacting with a single histidine residue in the carboxy terminal domain.J Physiol2016
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Collaborators

Stuart A Lipton
The Scripps Research Institute, University of California
Co-authored papers 9
Dorit Trudler
Tel Aviv University
Co-authored papers 7
Maria Talantova
The Scripps Research Institute
Co-authored papers 6
Tomohiro Nakamura
The Scripps Research Institute
Co-authored papers 5
Rajesh Ambasudhan
The Scripps Research Institute
Co-authored papers 3
Nima Dolatabadi
The Scripps Research Institute
Co-authored papers 3
John R Yates
TheScripps Research Institute
Co-authored papers 3
Ian A Wilson
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 2
Amanda J Roberts
The Scripps Research Institute
Co-authored papers 2
Malina A Bakowski
a division of The Scripps Research Institute La Jolla
Co-authored papers 2
Rommie E Amaro
University of California
Co-authored papers 2
Richard Gao
University of Tubingen
Co-authored papers 1
Yin Wu
The Scripps Research Institute
Co-authored papers 1
Abdullah Sultan
King Abdulaziz University
Co-authored papers 1
Eliezer Masliah
National Institute On Aging
Co-authored papers 1
Bradley Voytek
Alfred P. Sloan Foundation, National Academy of Sciences, University of California Berkeley, University of California San Diego, University of California, San Diego
Co-authored papers 1
Piotr Cieplak
Sanford-Burnham-Prebys Medical Discovery Institute
Co-authored papers 1
Xuemei Han
Co-authored papers 1
Gene W Yeo
University of California
Co-authored papers 1
Henry Scott
The Scripps Research Institute
Co-authored papers 1
Release 1.2