Author details

Full Name

Deborah E Leckband

Affiliation

ORCID

Career Start Year

1987

Papers

142

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37906737	Protein Folding Stability and Kinetics in Alginate Hydrogels.		2023
37757467	A computational study for understanding the impact of p120-catenin on the cis-dimerization of cadherin.		2023
34752975	Forces between mica and end-grafted statistical copolymers of sulfobetaine and oligoethylene glycol in aqueous electrolyte solutions.	Journal of Colloid and Interface Science	2022
35653290	Extracellular matrix regulates force transduction at VE-cadherin junctions.	Molecular Biology of the Cell	2022
36054903	Protein Stabilization by Alginate Binding and Suppression of Thermal Aggregation.	Biomacromolecules	2022
34392027	Ionic strength dependent forces between end-grafted Poly(sulfobetaine) films and mica.	Journal of Colloid and Interface Science	2022
35074920	Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor-dependent signaling.	Proceedings of the National Academy of Sciences of the United States of America	2022
34606244	Stabilization and Kinetics of an Adsorbed Protein Depends on the Poly(-isopropylacrylamide) Grafting Density.	Biomacromolecules	2021
34019823	P120 catenin potentiates constitutive E-cadherin dimerization at the plasma membrane and regulates trans binding.	Current Biology	2021
33658369	Cadherin cis and trans interactions are mutually cooperative.	Proceedings of the National Academy of Sciences of the United States of America	2021
32770112	Gold nanoparticles disrupt actin organization and pulmonary endothelial barriers.	Scientific Reports	2020
32065971	Comparative effects of N-cadherin protein and peptide fragments on mesenchymal stem cell mechanotransduction and paracrine function.	Biomaterials	2020
32876051	Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions.	eLife	2020
31335147	Cadherin Extracellular Domain Clustering in the Absence of -Interactions.	Journal of Physical Chemistry Letters	2019
30463880	N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability.	Journal of Cell Biology	2019
30951897	Graphene oxide substrates with N-cadherin stimulates neuronal growth and intracellular transport.		2019
30948425	VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism.	Journal of Cell Biology	2019
29487179	Epidermal growth factor receptor and integrins control force-dependent vinculin recruitment to E-cadherin junctions.	Journal of Cell Science	2018
30504777	Force-dependent allostery of the Î±-catenin actin-binding domain controls adherens junction dynamics and functions.	Nature Communications	2018
30064224	Soluble Zwitterionic Poly(sulfobetaine) Destabilizes Proteins.	Biomacromolecules	2018
29142072	Salt bridges gate Î±-catenin activation at intercellular junctions.	Mol Biol Cell	2018
28181573	Corrigendum: Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions.	Scientific Reports	2017
28553706	Direct Imaging of Protein Stability and Folding Kinetics in Hydrogels.	ACS applied materials & interfaces	2017
28624707	Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity.	Biomaterials	2017
27714010	Correction: Nanoscale mechanics guides cellular decision making.	Integrative Biology (United Kingdom)	2016
28503305	Three Dimensional Conjugation of Recombinant N-Cadherin to a Hydrogel for Anisotropic Neural Growth.	Journal of Materials Chemistry B	2016
26966187	E-cadherin-mediated force transduction signals regulate global cell mechanics.	Journal of Cell Science	2016
27009566	Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions.	Scientific Reports	2016
26875524	Constructing modular and universal single molecule tension sensor using protein G to study mechano-sensitive receptors.	Scientific Reports	2016
27317301	Dynamic Imaging Reveals Coordinate Effects of Cyclic Stretch and Substrate Stiffness on Endothelial Integrity.		2016
27477049	Nanoscale mechanics guides cellular decision making.	Integrative Biology (United Kingdom)	2016
27705773	A Computational Model for Kinetic Studies of Cadherin Binding and Clustering.	Biophysical Journal	2016
28002742	Cadherin Diffusion in Supported Lipid Bilayers Exhibits Calcium-Dependent Dynamic Heterogeneity.	Biophysical Journal	2016
26070562	Structural Determinants of the Mechanical Stability of Î±-Catenin.	J Biol Chem	2015
25544608	Dynamic visualization of Î±-catenin reveals rapid, reversible conformation switching between tension states.	Current Biology	2015
25663699	Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.	Journal of Cell Science	2015
25653389	Î±-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism.	Journal of Cell Science	2015
26361873	A genetic variant of cortactin linked to acute lung injury impairs lamellipodia dynamics and endothelial wound healing.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2015
26175155	Allosteric Regulation of E-Cadherin Adhesion.	Journal of Biological Chemistry	2015
25062360	Cadherin adhesion and mechanotransduction.	Annual Review of Cell and Developmental Biology	2014
25320070	Atomic force microscopy measurements reveal multiple bonds between Helicobacter pylori blood group antigen binding adhesin and Lewis b ligand.	Journal of the Royal Society Interface	2014
24773064	Recapitulating cell-cell adhesion using N-cadherin biologically tethered to substrates.	Biomacromolecules	2014
24522187	Î±-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction.	Journal of Cell Science	2014
23214990	Protein adsorption mechanisms determine the efficiency of thermally controlled cell adhesion on poly(N-isopropyl acrylamide) brushes.	Biomacromolecules	2013
24262826	Cell adhesion: sizing up a sticky situation.	Current Biology	2013
23831721	Bioengineered surfaces promote specific protein-glycan mediated binding of the gastric pathogen Helicobacter pylori.		2013
23600842	Poly(N-isopropyl acrylamide) brush topography: dependence on grafting conditions and temperature.	Langmuir	2013
23481397	N-cadherin regulates spatially polarized signals through distinct p120ctn and Î²-catenin-dependent signalling pathways.	Nature Communications	2013
23548927	Formin' cables under stress.	Nature Cell Biology	2013
23213393	Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation.	Biology Open	2012