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Author Details

Jeffery S Cox
University of California berkeley
1992
76
51
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37037941Autophagy restricts Mycobacterium tuberculosis during acute infection in mice.Nat Microbiol2023
37609245Mycobacterial formation of intracellular lipid inclusions is a dynamic process associated with rapid replication.bioRxiv2023
35073755Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms.mBio2022
35730550Workshop-based learning and networking: a scalable model for research capacity strengthening in low- and middle-income countries.Glob Health Action2022
34225486Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control <i>Mycobacterium tuberculosis</i> Infection in Macrophages.mBio2021
32404352TRIM14 Is a Key Regulator of the Type I IFN Response during <i>Mycobacterium tuberculosis</i> Infection.J Immunol2020
31951200Dynamic post-translational modification profiling of <i>Mycobacterium tuberculosis</i>-infected primary macrophages.Elife2020
32636381Interferon-independent STING signaling promotes resistance to HSV-1 in vivo.Nat Commun2020
32695111Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by <i>Mycobacterium tuberculosis</i> Expressed Determinants.Front Immunol2020
31204998Cas9<sup>+</sup> conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond.Elife2019
31611642Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence.Nat Microbiol2019
29279409<i>Listeria monocytogenes</i> triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy.Proc Natl Acad Sci U S A2018
30118682An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.Mol Cell2018
28762275Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells.ACS Infect Dis2017
28463648A Functional Toll-Interacting Protein Variant Is Associated with Bacillus Calmette-Guérin-Specific Immune Responses and Tuberculosis.Am J Respir Crit Care Med2017
28388411Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.Cell2017
27049940Immunology: Organelle stress triggers inflammation.Nature2016
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
25865481Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.Cell2015
26048136The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy.Cell Host Microbe2015
26118995Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.Cell Host Microbe2015
24994900Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi.Proc Natl Acad Sci U S A2014
25275011Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion.Proc Natl Acad Sci U S A2014
23475669Genetic and mass spectrometric tools for elucidating the physiological function(s) of cytochrome P450 enzymes from Mycobacterium tuberculosis.Methods Mol Biol2013
24255121cor, a novel carbon monoxide resistance gene, is essential for Mycobacterium tuberculosis pathogenesis.mBio2013
23881288Host-pathogen interactions during Mycobacterium tuberculosis infections.Curr Top Microbiol Immunol2013
23970558Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes.Science2013
23954156Salmonella require the fatty acid regulator PPARδ for the establishment of a metabolic environment essential for long-term persistence.Cell Host Microbe2013
24005326The ubiquitin ligase parkin mediates resistance to intracellular pathogens.Nature2013
22360425Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages.ACS Chem Biol2012
22901810Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway.Cell2012
22607800Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages.Cell Host Microbe2012
21795602EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins.Proc Natl Acad Sci U S A2011
22195552TB lipidomics--the final frontier.Chem Biol2011
20227664Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.Cell Host Microbe2010
20545858Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one.Mol Microbiol2010
19616759CarD tricks and magic spots: mechanisms of stringent control in mycobacteria.Cell Host Microbe2009
19876390Systematic genetic nomenclature for type VII secretion systems.PLoS Pathog2009
20011113Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution.PLoS Genet2009
19682254ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria.Mol Microbiol2009
18193943Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen.PLoS Pathog2008
18752626Protein tyrosine phosphatase PtpA is not required for Mycobacterium tuberculosis growth in mice.FEMS Microbiol Lett2008
18474359Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection.Cell Host Microbe2008
18503637ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection.Cell Microbiol2008
18685700Secreted transcription factor controls Mycobacterium tuberculosis virulence.Nature2008
18180457Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection.Proc Natl Acad Sci U S A2008
17420014Nippostrongylus brasiliensis: identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection.Exp Parasitol2007
17922044Type VII secretion--mycobacteria show the way.Nat Rev Microbiol2007
17592143PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1.Proc Natl Acad Sci U S A2007
17676952A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.PLoS Pathog2007
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Collaborators

Sarah A Stanley
University of California berkeley
Co-authored papers 7
Carolyn R Bertozzi
Stanford University
Co-authored papers 5
Robert O Watson
Texas A&M University School of Medicine
Co-authored papers 5
Peter Walter
University of California san francisco
Co-authored papers 5
Oren S Rosenberg
University of California san francisco
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 4
Samantha L Bell
College of Medicine, Rutgers New Jersey Medical School
Co-authored papers 4
Daniel A Portnoy
University of California berkeley
Co-authored papers 4
Guillaume Golovkine
University of California berkeley
Co-authored papers 4
Lauren M Popov
University of California berkeley
Co-authored papers 3
Robert M Stroud
University of California San Francisco
Co-authored papers 3
Jonathan M Budzik
University of California san francisco
Co-authored papers 3
Bennett H Penn
University of California Davis
Co-authored papers 3
Allison W Roberts
University of California berkeley
Co-authored papers 3
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 3
Janet Finer-Moore
University of California San Francisco
Co-authored papers 3
Christopher J Petzold
Joint BioEnergy Institute
Co-authored papers 3
Yamini M Ohol
University of California san francisco
Co-authored papers 3
Michael Rape
Howard Hughes Medical Institute, University of California at Berkeley
Co-authored papers 2
Erik Van Dis
University of California berkeley
Co-authored papers 2
Tom Alber
University of California berkeley
Co-authored papers 2
Teresa Repasy
University of California berkeley
Co-authored papers 2
John Von Dollen
University of California San Francisco
Co-authored papers 2
Chen Chen
University of California berkeley
Co-authored papers 2
David Jimenez-Morales
J. David Gladstone Institutes
Co-authored papers 2
Tasha Johnson
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 2
Matthew M Champion
Co-authored papers 2
Celine Perier
Vall d'Hebron Research Institute (VHIR)
Co-authored papers 2
Caroline E Shamu
Harvard Medical School
Co-authored papers 2
Stefanie J??ger
Institute of Molecular Biosciences, Goethe University Frankfurt
Co-authored papers 2
Release 1.2