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Author Details

Sabine M H??lter
German Research Centre for Environmental Health
1993
121
43
PMIDPaper TitleJournal TitlePublished Year
36148902Improving biomedical research by automated behaviour monitoring in the animal home cage - action needed for networking.Lab Anim2023
37953247A systematic review of the development and application of home cage monitoring in laboratory mice and rats.BMC Biol2023
37160609Knockout mouse models as a resource for the study of rare diseases.Mamm Genome2023
36993625Implication of FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT).medRxiv2023
37467750Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease.Am J Hum Genet2023
37230398AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease.Biochim Biophys Acta Mol Basis Dis2023
36538124A rationale for considering heart/brain axis control in neuropsychiatric disease.Mamm Genome2023
34964047Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.Dis Model Mech2022
35373464Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.EMBO Mol Med2022
36182809Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.Redox Biol2022
36369285Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.Nat Commun2022
36232867A Pathophysiological Intersection of Diabetes and Alzheimer's Disease.Int J Mol Sci2022
33264576Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.Int J Radiat Biol2021
34750991Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes.EMBO Mol Med2021
34028353Introduction to the EQIPD quality system.Elife2021
33131190Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.Brain Behav2021
32317624Polymorphisms in CRYBB2 encoding βB2-crystallin are associated with antisaccade performance and memory function.Transl Psychiatry2020
32060626A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.Mamm Genome2020
32066665A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.Transl Psychiatry2020
32593773Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.Neurosci Lett2020
32217665The rRNA m<sup>6</sup>A methyltransferase METTL5 is involved in pluripotency and developmental programs.Genes Dev2020
30557699A mouse model for intellectual disability caused by mutations in the X-linked 2'â¿¿Oâ¿¿methyltransferase Ftsj1 gene.Biochim Biophys Acta Mol Basis Dis2019
31862894Dusp8 affects hippocampal size and behavior in mice and humans.Sci Rep2019
31111503Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.J Inherit Metab Dis2019
30291584Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice.Mol Neurobiol2019
28695538Fgf9 <sup>Y162C</sup> Mutation Alters Information Processing and Social Memory in Mice.Mol Neurobiol2018
30040222Analysis of Neuropsychiatric Disease-Related Functional Neuroanatomical Markers in Mice.Curr Protoc Mouse Biol2018
30202017Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.Nat Microbiol2018
28483715Analysis of locomotor behavior in the German Mouse Clinic.J Neurosci Methods2018
28373690A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.Mol Psychiatry2018
29662492RNase H2 Loss in Murine Astrocytes Results in Cellular Defects Reminiscent of Nucleic Acid-Mediated Autoinflammation.Front Immunol2018
29659570Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.PLoS Biol2018
28966146Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.Behav Brain Res2018
29327260Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk.Radiat Environ Biophys2018
27914009Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.Mol Neurobiol2017
28111078Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis.Neuron2017
28409281Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.Acta Neuropathol2017
28334613Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis.Neuron2017
29261230Assessing Sociability, Social Memory, and Pup Retrieval in Mice.Curr Protoc Mouse Biol2017
28627418Alterations in neuronal control of body weight and anxiety behavior by glutathione peroxidase 4 deficiency.Neuroscience2017
28645892<i>Meis1</i>: effects on motor phenotypes and the sensorimotor system in mice.Dis Model Mech2017
28818080Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 <sup>I27N</sup> mutant mice.J Biomed Sci2017
28761067Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.Nat Commun2017
28576705The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse.Neurobiol Dis2017
27923998Interplay between H1 and HMGN epigenetically regulates OLIG1&amp;2 expression and oligodendrocyte differentiation.Nucleic Acids Res2017
27003440Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice.PLoS One2016
27815347The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.G3 (Bethesda)2016
25348795MiR-34a deficiency accelerates medulloblastoma formation in vivo.Int J Cancer2015
26629775Assessing Cognition in Mice.Curr Protoc Mouse Biol2015
26629773Tests for Anxiety-Related Behavior in Mice.Curr Protoc Mouse Biol2015
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Collaborators

Wolfgang Wurst
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 85
Martin Hrab?? de Angelis
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 78
Valerie Gailus-Durner
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 71
Helmut Fuchs
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 71
Jan Rozman
German Center for Diabetes Research (DZD)
Co-authored papers 36
Martin Klingenspor
Technical University of Munich
Co-authored papers 33
Nicole Ehrhardt
University of Washington
Co-authored papers 8
Glauco P Tocchini-Valentini
Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)
Co-authored papers 3
Sara Wells
Mary Lyon Centre at Medical Research Council
Co-authored papers 3
Thomas Meitinger
Technical University of Munich, Institute of Human Genetics
Co-authored papers 3
Juliane Winkelmann
Co-authored papers 3
Steve D M Brown
Mary Lyon Centre Harwell Science and Innovation Campus Oxfordshire UK.
Co-authored papers 3
Simon Greenaway
Harwell Institute
Co-authored papers 2
Luis Santos
The Turing Institute
Co-authored papers 2
Tim M Strom
Co-authored papers 2
John M Hancock
the University of Texas Health Science Center at Houston
Co-authored papers 2
David J Adams
Wellcome Sanger Institute
Co-authored papers 2
Yann Herault
Institut Clinique de la Souris (ICS), Universite de Strasbourg, CNRS, INSERM
Co-authored papers 2
Henrik Westerberg
MRC Harwell Institute
Co-authored papers 2
Fabian J Theis
Technical University of Munich
Co-authored papers 2
Hugh Morgan
MRC Harwell Institute
Co-authored papers 2
Klaus Schughart
University of Tennessee Health Science Center
Co-authored papers 2
Markus Ralser
Charite - Universitatsmedizin Berlin
Co-authored papers 2
Tania Sorg
Universite de Strasbourg, CNRS, INSERM, Institut de La Clinique de La Souris
Co-authored papers 2
Ann-Marie Mallon
The Turing Institute
Co-authored papers 2
Thomas Wieland
Co-authored papers 2
Jacqueline K White
Wellcome Trust Sanger Institute
Co-authored papers 2
Daniela Hoeller
Institute of Biochemistry II, Goethe University
Co-authored papers 1
Pieter Mestdagh
Co-authored papers 1
Thomas M Keane
European Bioinformatics Institute
Co-authored papers 1
Release 1.2