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Author Details

Ruth M Ruprecht
University of Texas San Antonio
1971
202
47
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37613382Elucidating Vaccine Trafficking Mechanisms using Multimodal Imaging.Microsc Microanal2023
35273592Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges.Front Immunol2022
35645210Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?Antibodies (Basel)2022
35857825Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity.Sci Transl Med2022
33385332Phage Display-Directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication.Mol Ther2021
33658998Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge.Front Immunol2021
34860581A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.Sci Immunol2021
34793582Localization of infection in neonatal rhesus macaques after oral viral challenge.PLoS Pathog2021
34402452Mucosal AIDS virus transmission is enhanced by antiviral IgG isolated early in infection.AIDS2021
34413855Cooperation Between Systemic IgG1 and Mucosal Dimeric IgA2 Monoclonal Anti-HIV Env Antibodies: Passive Immunization Protects Indian Rhesus Macaques Against Mucosal SHIV Challenges.Front Immunol2021
34061907PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure.PLoS Pathog2021
34091299Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates.Biomaterials2021
32343743Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.PLoS Pathog2020
32849652Immunoglobulin M: An Ancient Antiviral Weapon - Rediscovered.Front Immunol2020
32130229Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques.PLoS One2020
30760566Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade A Envelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants.J Virol2019
31771162Mucosal Antibodies: Defending Epithelial Barriers against HIV-1 Invasion.Vaccines (Basel)2019
31035848Lymphocytes upregulate CD36 in adipose tissue and liver.Adipocyte2019
29093095Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge.J Virol2018
29743361Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying <i>env</i> from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism.J Virol2018
29762161Anti-HIV IgM protects against mucosal SHIV transmission.AIDS2018
29563297Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques.J Virol2018
29097089Anti-HIV Passive Immunization: New Weapons in the Arsenal.Trends Microbiol2017
28463876Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV.AIDS2017
28422786Antibody-mediated immune exclusion of HIV.Curr Opin HIV AIDS2017
29176985Mucosal IgA Responses: Damaged in Established HIV Infection-Yet, Effective Weapon against HIV Transmission.Front Immunol2017
25174584Massive occlusive thrombosis of the pulmonary artery in pigtailed macaques chronically infected with R5-tropic simian-human immunodeficiency virus.J Med Primatol2015
25769884Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge.Vaccine2015
24444350Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose.Retrovirology2014
25499540Are anti-HIV IgAs good guys or bad guys?Retrovirology2014
25245933Multimodality vaccination against clade C SHIV: partial protection against mucosal challenges with a heterologous tier 2 virus.Vaccine2014
23528732Impact of antibody quality and anamnestic response on viremia control post-challenge in a combined Tat/Env vaccine regimen in rhesus macaques.Virology2013
24278022The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.PLoS Pathog2013
24098702Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques.PLoS One2013
23840566Variations in the Biological Functions of HIV-1 Clade C Envelope in a SHIV-Infected Rhesus Macaque during Disease Progression.PLoS One2013
23775002Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission.AIDS2013
23800339Live-virus exposure of vaccine-protected macaques alters the anti-HIV-1 antibody repertoire in the absence of viremia.Retrovirology2013
23758766Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence.Retrovirology2013
23388727Novel biopanning strategy to identify epitopes associated with vaccine protection.J Virol2013
21941166High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia.AIDS2012
22970187Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.PLoS One2012
22737224Isolation of monoclonal antibodies with predetermined conformational epitope specificity.PLoS One2012
22828501Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.Mol Ther2012
22427893Dynamics of envelope evolution in clade C SHIV-infected pig-tailed macaques during disease progression analyzed by ultra-deep pyrosequencing.PLoS One2012
21244649Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV.J Immune Based Ther Vaccines2011
22081778No acquisition: a new ambition for HIV vaccine development?Curr Opin Virol2011
21829749Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 Clade C SHIV.PLoS Negl Trop Dis2011
21799765Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.PLoS One2011
21895680Molecularly cloned SHIV-CN97001: a replication-competent, R5 simian/human immunodeficiency virus containing env of a primary Chinese HIV-1 clade C isolate.J Med Primatol2011
21957314Efficiency of neutralizing antibodies targeting the CD4-binding site: influence of conformational masking by the V2 loop in R5-tropic clade C simian-human immunodeficiency virus.J Virol2011
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Collaborators

Co-authored papers 31
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Co-authored papers 26
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The University of Texas MD Anderson Cancer Center
Co-authored papers 6
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Co-authored papers 6
Harvard School of Public Health
Co-authored papers 5
University of Virginia
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
Co-authored papers 3
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Boston Children's Hospital
Co-authored papers 3
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 2
Co-authored papers 2
Texas Biomedical Research Institute
Co-authored papers 2
Co-authored papers 2
Texas Biomedical Research Institute
Co-authored papers 2
Frederick National Laboratory
Co-authored papers 2
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Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 1
The Wistar Institute
Co-authored papers 1
University of Massachusetts School of Medicine
Co-authored papers 1