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Author Details

Jana Krosl
The Leucegene Project at Institute for Research in Immunology and Cancer.
1989
39
27
Sami Nourreddine (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34731885Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.Blood Adv2022
31300747Genetic characterization of ABT-199 sensitivity in human AML.Leukemia2020
31287994Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.Cancer Cell2019
29550835Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin.Leukemia2018
28855357Chemogenomic Landscape of <i>RUNX1</i>-mutated AML Reveals Importance of <i>RUNX1</i> Allele Dosage in Genetics and Glucocorticoid Sensitivity.Clin Cancer Res2017
28211886A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens.Blood Cancer J2017
27034432Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors.Blood2016
27797342High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.J Clin Invest2016
26834243GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.Blood2016
26237430The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias.Nat Genet2015
24562423Identification of small molecules that support human leukemia stem cell activity ex vivo.Nat Methods2014
24532712The methyltransferase G9a regulates HoxA9-dependent transcription in AML.Genes Dev2014
23592435Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia.Stem Cells2013
23777767RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.Blood2013
22431509A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia.Genes Dev2012
21541287Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway.PLoS One2011
21900201C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.Blood2011
20522713A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations.Blood2010
21170304Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions.PLoS Genet2010
18679416Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia.Oncogene2008
17577929Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells.Exp Hematol2007
16339407Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells.Blood2006
16469876Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation.Blood2006
15226173Molecular interactions involved in HOXB4-induced activation of HSC self-renewal.Blood2004
15190292Molecular basis for stem-cell self-renewal.Hematol J2004
12705858The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential.Immunity2003
14578881In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein.Nat Med2003
11064450AP-1 complex is effector of Hox-induced cellular proliferation and transformation.Oncogene2000
10454582The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells.Mol Cell Biol1999
9692548Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1.Oncogene1998
9657741The hyperresponsiveness of cells expressing truncated erythropoietin receptors is contingent on insulin-like growth factor-1 in fetal calf serum.Blood1998
9649441Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.EMBO J1998
9209412The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.Leukemia1997
8764122Potentiation of photodynamic therapy-elicited antitumor response by localized treatment with granulocyte-macrophage colony-stimulating factor.Cancer Res1996
8971170The role of host lymphoid populations in the response of mouse EMT6 tumor to photodynamic therapy.Cancer Res1996
8910323Interleukin-3 (IL-3) inhibits erythropoietin-induced differentiation in Ba/F3 cells via the IL-3 receptor alpha subunit.J Biol Chem1996
7803809Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells.Blood1995
8521813Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.EMBO J1995
2770296Prolonged cultivation of rat uterine cells with preserved estrogen responsiveness.J Steroid Biochem1989
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Collaborators

Universite de Montreal
Co-authored papers 30
Universite de Montreal
Co-authored papers 13
Institute for Research in Immunology and Cancer
Co-authored papers 10
Institute for Research in Immunology and Cancer, University of Montreal
Co-authored papers 8
University of Montreal
Co-authored papers 5
Institute for Research in Immunology and Cancer
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 2
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 2
Universite de Montreal, Institute for Research in Immunology and Cancer
Co-authored papers 2
IRIC - University of Montreal
Co-authored papers 2
Department of Biomedical Science and Center for Bio-Nanomaterials, Daegu University
Co-authored papers 2
University of Iceland
Co-authored papers 2
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 2
Universite de Montreal, Institute for Research in Immunology and Cancer
Co-authored papers 1
McGill University
Co-authored papers 1
Walter and Eliza Hall Institute of Medical Research
Co-authored papers 1
Universite de Toulouse, Inserm, Universite Toulouse III-Paul Sabatier
Co-authored papers 1
Peking University Third Hospital
Co-authored papers 1
University of Campinas (UNICAMP)
Co-authored papers 1
Institute for Research in Immunology and Cancer (IRIC)
Co-authored papers 1
Leslie Dan Faculty of Pharmacy and Department of Biochemistry, University of Toronto
Co-authored papers 1
University of California San Diego
Co-authored papers 1
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Universite de Montreal
Co-authored papers 1
University of British Columbia
Co-authored papers 1
McGill University
Co-authored papers 1
Centre Hospitalier Universitaire Sainte-Justine
Co-authored papers 1
Centre hospitalier universitaire de l'Universite de Montreal (CHUM)
Co-authored papers 1
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Co-authored papers 1
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 1