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Author Details
Full Name
Jana Krosl
Affiliation
The Leucegene Project at Institute for Research in Immunology and Cancer.
ORCID
Career Start Year
1989
Papers
39
H Index
27
Expertise
CM4AI Collaborator
Sami Nourreddine (CM4AI)
PMID
Paper Title
Journal Title
Published Year
34731885
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.
Blood Adv
2022
31300747
Genetic characterization of ABT-199 sensitivity in human AML.
Leukemia
2020
31287994
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Cancer Cell
2019
29550835
Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin.
Leukemia
2018
28855357
Chemogenomic Landscape of <i>RUNX1</i>-mutated AML Reveals Importance of <i>RUNX1</i> Allele Dosage in Genetics and Glucocorticoid Sensitivity.
Clin Cancer Res
2017
28211886
A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens.
Blood Cancer J
2017
27034432
Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors.
Blood
2016
27797342
High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.
J Clin Invest
2016
26834243
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.
Blood
2016
26237430
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias.
Nat Genet
2015
24562423
Identification of small molecules that support human leukemia stem cell activity ex vivo.
Nat Methods
2014
24532712
The methyltransferase G9a regulates HoxA9-dependent transcription in AML.
Genes Dev
2014
23592435
Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia.
Stem Cells
2013
23777767
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
Blood
2013
22431509
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia.
Genes Dev
2012
21541287
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway.
PLoS One
2011
21900201
C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.
Blood
2011
20522713
A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations.
Blood
2010
21170304
Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions.
PLoS Genet
2010
18679416
Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia.
Oncogene
2008
17577929
Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells.
Exp Hematol
2007
16339407
Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells.
Blood
2006
16469876
Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation.
Blood
2006
15226173
Molecular interactions involved in HOXB4-induced activation of HSC self-renewal.
Blood
2004
15190292
Molecular basis for stem-cell self-renewal.
Hematol J
2004
12705858
The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential.
Immunity
2003
14578881
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein.
Nat Med
2003
11064450
AP-1 complex is effector of Hox-induced cellular proliferation and transformation.
Oncogene
2000
10454582
The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells.
Mol Cell Biol
1999
9692548
Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1.
Oncogene
1998
9657741
The hyperresponsiveness of cells expressing truncated erythropoietin receptors is contingent on insulin-like growth factor-1 in fetal calf serum.
Blood
1998
9649441
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.
EMBO J
1998
9209412
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.
Leukemia
1997
8764122
Potentiation of photodynamic therapy-elicited antitumor response by localized treatment with granulocyte-macrophage colony-stimulating factor.
Cancer Res
1996
8971170
The role of host lymphoid populations in the response of mouse EMT6 tumor to photodynamic therapy.
Cancer Res
1996
8910323
Interleukin-3 (IL-3) inhibits erythropoietin-induced differentiation in Ba/F3 cells via the IL-3 receptor alpha subunit.
J Biol Chem
1996
7803809
Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells.
Blood
1995
8521813
Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.
EMBO J
1995
2770296
Prolonged cultivation of rat uterine cells with preserved estrogen responsiveness.
J Steroid Biochem
1989
1 - 39 of 39
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