Author details

Full Name

Craig C Mello

Affiliation

ORCID

Career Start Year

1985

Papers

109

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37384599	The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods.		2023
37609319	Casein kinase II promotes piRNA production through direct phosphorylation of USTC component TOFU-4.		2023
37083324	The nuclear Argonaute HRDE-1 directs target gene re-localization and shuttles to nuage to promote small RNA-mediated inherited silencing.		2023
36070689	A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing.	Cell Rep	2022
34547227	Cues from mRNA splicing prevent default Argonaute silencing in C.Â elegans.	Developmental Cell	2021
34003111	PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans.	Elife	2021
34003109	HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans.	Elife	2021
33658512	Germ granule dysfunction is a hallmark and mirror of Piwi mutant sterility.	Nature Communications	2021
33378643	The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C.Â elegans.	Mol Cell	2021
34505086	Microinjection for precision genome editing in .	STAR Protocols	2021
34665130	5'-Modifications improve potency and efficacy of DNA donors for precision genome editing.	eLife	2021
32963112	Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in .	Genetics	2020
29775580	ZNFX-1 Functions within Perinuclear Nuage to Balance Epigenetic Signals.	Molecular Cell	2018
32550369	A model for the rare human channelopathy, Timothy syndrome type 1.		2018
30213854	Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in .	Genetics	2018
30624949	Blood chimerism in twins.	Immunohematology	2018
29456136	A Sex Chromosome piRNA Promotes Robust Dosage Compensation and Sex Determination in C.Â elegans.	Dev Cell	2018
29456100	The Coding Regions of Germline mRNAs Confer Sensitivity to Argonaute Regulation in C.Â elegans.	Cell Rep	2018
29456082	Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C.Â elegans Germline.	Cell	2018
28262484	The Antiviral RNA Interference Response Provides Resistance to Lethal Arbovirus Infection and Vertical Transmission in Caenorhabditis elegans.	Current Biology	2017
27718356	A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes.	Elife	2016
26919432	The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans.	Cell	2016
26721685	Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals.	Science	2016
26584643	Associations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka species.	BMC Genomics	2015
25635455	A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi.	Cell	2015
25691467	Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF.	Genes Dev	2015
25559107	RNA Interference in Caenorhabditis elegans.	Current Protocols in Molecular Biology	2015
26096734	POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA.	Dev Cell	2015
26428694	Influenza A virus preferentially snatches noncoding RNA caps.	RNA	2015
26034705	RNA interference-mediated antiviral defense in insects.	Current Opinion in Insect Science	2015
24684931	The Vasa Homolog RDE-12 engages target mRNA and multiple argonaute proteins to promote RNAi in C. elegans.	Current Biology	2014
24675894	Divide and differentiate: CDK/Cyclins and the art of development.	Cell Cycle	2014
24966209	A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection.	Elife	2014
24879462	A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans.	Genetics	2014
24524013	Inductive asymmetric cell division: The WRM leads the way.		2013
24360782	The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression.	Developmental Cell	2013
24360276	Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans.	Cell	2013
23431196	Wnt and CDK-1 regulate cortical release of WRM-1/Î²-catenin to control cell division orientation in early Caenorhabditis elegans embryos.	Proceedings of the National Academy of Sciences of the United States of America	2013
23260138	CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors.	Cell	2012
22738726	piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.	Cell	2012
22738724	C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts.	Cell	2012
22773104	The translin-TRAX complex (C3PO) is a ribonuclease in tRNA processing.	Nature Structural and Molecular Biology	2012
23200856	Specific miRNA stabilization by Gld2-catalyzed monoadenylation.	Cell Reports	2012
23141544	Protection from feed-forward amplification in an amplified RNAi mechanism.	Cell	2012
22179787	Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi.	Nat Struct Mol Biol	2011
21179009	MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression.	Mol Ther	2011
21528459	Cloning Argonaute-associated small RNAs from Caenorhabditis elegans.	Methods in Molecular Biology	2011
20059995	NMY-2 maintains cellular asymmetry and cell boundaries, and promotes a SRC-dependent asymmetric cell division.	Developmental Biology	2010
20178736	Primal RNAs: The end of the beginning?	Cell	2010
20133686	Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans.	Proceedings of the National Academy of Sciences of the United States of America	2010