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Author Details

Chance John Luckey
University of Virginia School of Medicine.
1995
46
22
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36373252Identification of multiple genetic loci associated with red blood cell alloimmunization in mice.Haematologica2023
37363865Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression.Blood2023
36436200The role of RBC antigen transgene integration sites on RBC biology in mice.Transfusion2023
36712006Class switching is differentially regulated in RBC alloimmunization and vaccination.bioRxiv2023
36838135A Scalable, Modular Degasser for Passive In-Line Removal of Bubbles from Biomicrofluidic Devices.Micromachines (Basel)2023
36907655Class switching is differentially regulated in RBC alloimmunization and vaccination.Transfusion2023
36708051Storage differentially impacts alloimmunization to distinct red cell antigens following transfusion in mice.Transfusion2023
36638335Prior immunization against an intracellular antigen enhances subsequent red blood cell alloimmunization in mice.Blood2023
35241129Enhanced protein isoform characterization through long-read proteogenomics.Genome Biol2022
35470900Clodronate inhibits alloimmunization against distinct red blood cell alloantigens in mice.Transfusion2022
35670632Retention of functional mitochondria in mature red blood cells from patients with sickle cell disease.Br J Haematol2022
35535262Towards spatially-organized organs-on-chip: Photopatterning cell-laden thiol-ene and methacryloyl hydrogels in a microfluidic device.Organs Chip2022
36278434Somatic mutations show no clear association with red blood cell or human leukocyte antigen alloimmunization in de novo or therapy-related myelodysplastic syndrome.Transfusion2022
36189253Fc<i>γ</i>RIV is required for IgG2c mediated enhancement of RBC alloimmunization.Front Immunol2022
35039331Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88.J Immunol2022
34181769The lysophospholipid-binding molecule CD1D is not required for the alloimmunization response to fresh or stored RBCs in mice despite RBC storage driving alterations in lysophospholipids.Transfusion2021
33712594Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia.Nat Commun2021
33777014Antibodies to Low-Copy Number RBC Alloantigen Convert a Tolerogenic Stimulus to an Immunogenic Stimulus in Mice.Front Immunol2021
34249009Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice.Front Immunol2021
32266378Poly(I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice.Blood2020
31355970Red blood cell alloimmunization is associated with lower expression of FcγR1 on monocyte subsets in patients with sickle cell disease.Transfusion2019
26768686Infused total nucleated cell dose is a better predictor of transplant outcomes than CD34+ cell number in reduced-intensity mobilized peripheral blood allogeneic hematopoietic cell transplantation.Haematologica2016
27662015Interleukin-6 receptor-alpha signaling drives anti-RBC alloantibody production and T-follicular helper cell differentiation in a murine model of red blood cell alloimmunization.Haematologica2016
25363779Genetic and epigenetic fine mapping of causal autoimmune disease variants.Nature2015
24724792Blood and bombs: blood use after the Boston Marathon bombing of April 15, 2013.Transfusion2014
24813856Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells.Cell Stem Cell2014
23970354A mouse model of hemolytic disease of the newborn.Blood2013
24060676Culture of mouse amniotic fluid-derived cells on irradiated STO feeders results in the generation of primitive endoderm cell lines capable of self-renewal in vitro.Cells Tissues Organs2013
23863870Genome-scale proteome quantification by DEEP SEQ mass spectrometry.Nat Commun2013
22305557Stem-cell-like qualities of immune memory; CD4+ T cells join the party.Cell Stem Cell2012
22474248C/EBPα and DEK coordinately regulate myeloid differentiation.Blood2012
21788404Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis.Mol Cell Proteomics2011
22074622Understanding the first steps in embryonic stem cell exit from the pluripotent state.Transfusion2011
20019052A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia.Mol Cell Proteomics2010
19331382Improved electrospray ionization efficiency compensates for diminished chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells.Anal Chem2009
16492737Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.Proc Natl Acad Sci U S A2006
16785882Gene expression microarrays: glimpses of the immunological genome.Nat Immunol2006
15548615The molecular program induced in T cells undergoing homeostatic proliferation.Proc Natl Acad Sci U S A2004
14607930Tapasin is a facilitator, not an editor, of class I MHC peptide binding.J Immunol2003
12391225Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets.J Immunol2002
11172025Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).Proc Natl Acad Sci U S A2001
11466336Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors.J Immunol2001
10748239Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: implications for tumor immunotherapy.J Exp Med2000
9647214Proteasomes can either generate or destroy MHC class I epitopes: evidence for nonproteasomal epitope generation in the cytosol.J Immunol1998
9419209The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol.J Exp Med1998
7547687Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice.Int Immunol1995
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Collaborators

Center for Transfusion and Cellular Therapy, Emory University School of Medicine
Co-authored papers 13
Columbia University Irving Medical Center, New York-Presbyterian Hospital
Co-authored papers 12
University of Virginia
Co-authored papers 10
University of Virginia School of Medicine
Co-authored papers 8
University of Virginia
Co-authored papers 6
University of Virginia
Co-authored papers 6
Massachusetts Institute of Technology
Co-authored papers 4
Emory University School of Medicine
Co-authored papers 4
University of Virginia School of Medicine, University of Virginia.
Co-authored papers 3
University of Virginia
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Broad Institute of Harvard and MIT
Co-authored papers 2
Co-authored papers 2
University of Virginia School of Medicine.
Co-authored papers 2
University of Virginia
Co-authored papers 2
Co-authored papers 2
University of Wisconsin-Madison
Co-authored papers 1
University of Alabama at Birmingham
Co-authored papers 1
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 1
University of Virginia
Co-authored papers 1
Institute for Integrative Systems Biology, Spanish National Research Council (CSIC)
Co-authored papers 1
Co-authored papers 1
University of Virginia School of Medicine
Co-authored papers 1
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 1
Columbia University Irving Medical Center, New York-Presbyterian Hospital
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Massachusetts General Hospital
Co-authored papers 1
Broad Institute of MIT and Harvard
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Columbia University Irving Medical Center, New York-Presbyterian Hospital
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David Geffen School of Medicine at university of california los angeles
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