|
| 37461624 | Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies <i>LRRC4C, LHX5-AS1</i> and nominates ancestry-specific loci <i>PTPRK</i> , <i>GRB14</i> , and <i>KIAA0825</i> as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. | medRxiv | 2023 |
| 37919278 | Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy. | Nat Commun | 2023 |
| 37546878 | Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer's disease and progressive supranuclear palsy. | medRxiv | 2023 |
| 37016279 | Titration-based normalization of antibody amount improves consistency of ChIP-seq experiments. | BMC Genomics | 2023 |
| 37429840 | Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer's disease. | NPJ Regen Med | 2023 |
| 34482628 | Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans. | Alzheimers Dement | 2022 |
| 35829654 | The landscape of metabolic brain alterations in Alzheimer's disease. | Alzheimers Dement | 2022 |
| 35388616 | Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations. | Aging Cell | 2022 |
| 35897046 | Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways. | Alzheimers Res Ther | 2022 |
| 34918867 | Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease. | Alzheimers Dement | 2022 |
| 35047668 | Clinical Deep Phenotyping of <i>ABCA7</i> Mutation Carriers. | Neurol Genet | 2022 |
| 34813500 | Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions. | J Clin Invest | 2022 |
| 33480174 | Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. | Alzheimers Dement | 2021 |
| 33765507 | Analysis of intraoperative human brain tissue transcriptome reveals putative risk genes and altered molecular pathways in glioma-related seizures. | Epilepsy Res | 2021 |
| 33875655 | Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer's disease. | Nat Commun | 2021 |
| 33726851 | Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease. | Acta Neuropathol Commun | 2021 |
| 33635380 | Latent trait modeling of tau neuropathology in progressive supranuclear palsy. | Acta Neuropathol | 2021 |
| 34857756 | Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. | Nat Commun | 2021 |
| 34020725 | Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. | Acta Neuropathol Commun | 2021 |
| 34127518 | Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo. | Life Sci Alliance | 2021 |
| 33957936 | Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy. | Mol Neurodegener | 2021 |
| 33417599 | Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome. | PLoS Genet | 2021 |
| 32400971 | MAPT haplotype-stratified GWAS reveals differential association for AD risk variants. | Alzheimers Dement | 2020 |
| 34393677 | EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE ε4 ON ALZHEIMER'S DISEASE RISK IN HUMANS. | Alzheimers Dement | 2020 |
| 31955222 | Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. | Acta Neuropathol | 2020 |
| 33046718 | Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions. | Sci Data | 2020 |
| 33092647 | Association of ABI3 and PLCG2 missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy. | Acta Neuropathol Commun | 2020 |
| 32660529 | Deciphering cellular transcriptional alterations in Alzheimer's disease brains. | Mol Neurodegener | 2020 |
| 32827351 | Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease. | Alzheimers Dement | 2020 |
| 32928256 | Correction to: Deciphering cellular transcriptional alterations in Alzheimer's disease brains. | Mol Neurodegener | 2020 |
| 32755048 | Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology. | Alzheimers Dement | 2020 |
| 32668255 | Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. | Cell Rep | 2020 |
| 30820047 | Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. | Nat Genet | 2019 |
| 29329552 | Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience. | Genome Med | 2018 |
| 30078640 | An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor. | Neurobiol Aging | 2018 |
| 30158114 | TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. | J Exp Med | 2018 |
| 29970152 | TMEM106B haplotypes have distinct gene expression patterns in aged brain. | Mol Neurodegener | 2018 |
| 30136084 | Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy. | Acta Neuropathol | 2018 |
| 30326945 | ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans. | Mol Neurodegener | 2018 |
| 29458411 | Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. | Alzheimers Res Ther | 2018 |
| 29107053 | Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. | Alzheimers Dement | 2018 |
| 27939925 | A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression. | Alzheimers Dement | 2017 |
| 28106563 | Comprehensive Screening for Disease Risk Variants in Early-Onset Alzheimer's Disease Genes in African Americans Identifies Novel PSEN Variants. | J Alzheimers Dis | 2017 |
| 28480329 | African American exome sequencing identifies potential risk variants at Alzheimer disease loci. | Neurol Genet | 2017 |
| 28242297 | Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments. | Alzheimers Dement | 2017 |
| 28097223 | <i>ABCA7</i> loss-of-function variants, expression, and neurologic disease risk. | Neurol Genet | 2017 |
| 29183403 | Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience. | Genome Med | 2017 |
| 28714976 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. | Nat Genet | 2017 |
| 27287057 | MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies. | Alzheimers Dement | 2016 |
| 27727239 | Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases. | Sci Data | 2016 |