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Author Details

Sean K Simmons
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard
2015
26
13
PMIDPaper TitleJournal TitlePublished Year
36109685Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing.Nat Biotechnol2023
37657442Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.Neuron2023
37790302Massively parallel <i>in vivo</i> Perturb-seq reveals cell type-specific transcriptional networks in cortical development.bioRxiv2023
37188501A single-cell map of antisense oligonucleotide activity in the brain.Nucleic Acids Res2023
37337297The effect of background noise and its removal on the analysis of single-cell expression data.Genome Biol2023
37292843Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling.Res Sq2023
36824749A single-cell map of antisense oligonucleotide activity in the brain.bioRxiv2023
35110736Autism genes converge on asynchronous development of shared neuron classes.Nature2022
33663567Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.Genome Biol2021
32341560Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.Nat Biotechnol2020
31928904Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders.Eur J Paediatr Neurol2020
33243861In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes.Science2020
32699411Distinct subnetworks of the thalamic reticular nucleus.Nature2020
32359425Privacy-Preserving Biomedical Database Queries with Optimal Privacy-Utility Trade-Offs.Cell Syst2020
32341567Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.Nat Biotechnol2020
30963078Protecting Genomic Data Privacy with Probabilistic Modeling.Pac Symp Biocomput2019
31551601Single-cell transcriptomic profiling of the aging mouse brain.Nat Neurosci2019
31168097Individual brain organoids reproducibly form cell diversity of the human cerebral cortex.Nature2019
30446528Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of <i>ERAP2</i> transcripts under balancing selection.Genome Res2018
29867192Comprehensive comparative analysis of 5'-end RNA-sequencing methods.Nat Methods2018
30271673Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons.Nat Biomed Eng2018
30459407Author Correction: Comprehensive comparative analysis of 5'-end RNA-sequencing methods.Nat Methods2018
26769317Realizing privacy preserving genome-wide association studies.Bioinformatics2016
27453444Enabling Privacy-Preserving GWASs in Heterogeneous Human Populations.Cell Syst2016
26098139Discovering What Dimensionality Reduction Really Tells Us About RNA-Seq Data.J Comput Biol2015
29202050One Size Doesn't Fit All: Measuring Individual Privacy in Aggregate Genomic Data.Proc IEEE Symp Secur Priv Workshops2015
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Collaborators

Broad Institute of MIT and Harvard
Co-authored papers 10
Massachusetts Institute of Technology
Co-authored papers 6
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Broad Institute of MIT and Harvard
Co-authored papers 3
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
UK Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge
Co-authored papers 2
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Glasgow
Co-authored papers 1
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
University of Toronto
Co-authored papers 1
McGovern Institute for Brain Research
Co-authored papers 1
Barcelona Institute of Science and Technology, Spain Universitat Pompeu Fabra
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Genentech Inc.
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Co-authored papers 1
University of Illinois
Co-authored papers 1
Pfizer Global Research and Development La Jolla
Co-authored papers 1
Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Stanford University, Yale University
Co-authored papers 1
Columbia University Medical Center
Co-authored papers 1