Author details

Full Name

Xiang Zhou

Affiliation

ORCID

Career Start Year

2012

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37169753	meQTL mapping in the GENOA study reveals genetic determinants of DNA methylation in African Americans.	Nat Commun	2023
37662416	Proteome-Wide Association Studies for Blood Lipids and Comparison with Transcriptome-Wide Association Studies.	bioRxiv	2023
37716346	mtPGS: Leverage multiple correlated traits for accurate polygenic score construction.		2023
37565565	Thyroid hormone-responsive protein mediates the response of chicken liver to fasting mainly through the cytokine-cytokine receptor interaction pathway.		2023
36753304	Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis.		2023
37127916	Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase-Signal Transducers and Activators of Transcription Signaling.		2023
37442575	Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution.		2023
37315093	Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals.		2023
36869394	SRTsim: spatial pattern preserving simulations for spatially resolved transcriptomics.		2023
34697824	Optimal diagnostic test allocation strategy during the COVID-19 pandemic and beyond.	Stat Med	2022
36374587	Fibromuscular Dysplasia and Abdominal Aortic Aneurysms Are Dimorphic Sex-Specific Diseases With Shared Complex Genetic Architecture.	Circ Genom Precis Med	2022
35585605	Modeling zero inflation is not necessary for spatial transcriptomics.		2022
36227056	Network regression analysis for binary and ordinal categorical phenotypes in transcriptome-wide association studies.	Genetics	2022
35501392	Spatially informed cell-type deconvolution for spatial transcriptomics.	Nature Biotechnology	2022
35927760	BASS: multi-scale and multi-sample analysis enables accurate cell type clustering and spatial domain detection in spatial transcriptomic studies.		2022
35731210	Statistical analysis of spatially resolved transcriptomic data by incorporating multiomics auxiliary information.	Genetics	2022
35727054	Genome-Based Assessment of Antimicrobial Resistance and Virulence Potential of Isolates of Non-Pullorum/Gallinarum Salmonella Serovars Recovered from Dead Poultry in China.	Microbiology spectrum	2022
35665255	DNA Methylation Mediates the Association Between Individual and Neighborhood Social Disadvantage and Cardiovascular Risk Factors.	Front Cardiovasc Med	2022
36418351	Spatially aware dimension reduction for spatial transcriptomics.	Nature Communications	2022
35334221	METRO: Multi-ancestry transcriptome-wide association studies for powerful gene-trait association detection.	Am J Hum Genet	2022
35039093	Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA).	Clin Epigenetics	2022
35193147	PGS-server: accuracy, robustness and transferability of polygenic score methods for biobank scale studies.	Briefings in Bioinformatics	2022
34411094	Multi-scale inference of genetic trait architecture using biologically annotated neural networks.	PLoS Genet	2021
35433074	Transcriptome-wide association studies: a view from Mendelian randomization.	Quantitative Biology	2021
34154649	SPARK-X: non-parametric modeling enables scalable and robust detection of spatial expression patterns for large spatial transcriptomic studies.		2021
33726838	Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans.	Clin Epigenetics	2021
33615361	Aggregating multiple expression prediction models improves the power of transcriptome-wide association studies.	Human Molecular Genetics	2021
34141140	Statistical methods for mediation analysis in the era of high-throughput genomics: Current successes and future challenges.	Computational and Structural Biotechnology Journal	2021
34356065	Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations.	Genes (Basel)	2021
33100131	Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans.	Epigenetics	2021
32790868	Efficient and effective control of confounding in eQTL mapping studies through joint differential expression and Mendelian randomization analyses.		2021
33395406	Accurate genetic and environmental covariance estimation with composite likelihood in genome-wide association studies.	PLoS Genetics	2021
33434493	Multi-trait transcriptome-wide association studies with probabilistic Mendelian randomization.	American Journal of Human Genetics	2021
34488438	Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease.	Hypertension	2021
34379090	Mendelian randomization under the omnigenic architecture.	Briefings in Bioinformatics	2021
34487140	Joint eQTL mapping and inference of gene regulatory network improves power of detecting both cis- and trans-eQTLs.		2021
34529658	On cross-ancestry cancer polygenic risk scores.	PLoS Genetics	2021
32840624	Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies Suggestive Loci for Sodium Intake, Potassium Intake, and Their Ratio Measured from 24-Hour or Half-Day Urine Samples.	J Nutr	2020
32310941	Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies.	PLoS Genetics	2020
32220292	Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA.	Am J Hum Genet	2020
31988518	Statistical analysis of spatial expression patterns for spatially resolved transcriptomic studies.	Nature Methods	2020
32458983	Single-Cell Analysis of the Gene Expression Effects of Developmental Lead (Pb) Exposure on the Mouse Hippocampus.	Toxicological Sciences	2020
32330416	Accurate and Scalable Construction of Polygenic Scores in Large Biobank Data Sets.	American Journal of Human Genetics	2020
33584792	A Review of Statistical Methods for Identifying Trait-Relevant Tissues and Cell Types.	Frontiers in Genetics	2020
32991828	Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks.	American Journal of Human Genetics	2020
32887874	Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction.	Nat Commun	2020
33371893	Pinpointing miRNA and genes enrichment over trait-relevant tissue network in Genome-Wide Association Studies.	BMC Medical Genomics	2020
33193711	Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization Approaches.	Frontiers in Genetics	2020
32917208	Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study.	BMC Med Genomics	2020
32637052	Statistical methods for SNP heritability estimation and partition: A review.	Computational and Structural Biotechnology Journal	2020