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Author Details

Gina M DeNicola
H. Lee. Moffitt Cancer Center
2005
66
28
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36862034Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.Cancer Res2023
37560930A PI3K gene expression signature predicts for recurrence in early-stage non-small cell lung cancer treated with stereotactic body radiation therapy.Cancer2023
37546939Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.bioRxiv2023
37873453ASCT2 is the primary serine transporter in cancer cells.bioRxiv2023
37258755Quantification and Tracing of Stable Isotope into Cysteine and Glutathione.Methods Mol Biol2023
37024755GAPDH redox redux-rewiring pentose phosphate flux.Nat Metab2023
37285264Retraction Notice to: mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation.Cell Rep2023
37062029Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.Cancer Res2023
36841051NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis.Redox Biol2023
36798186Glutathione supports lipid abundance <i>in vivo</i>.bioRxiv2023
36897780Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans.Cell Rep2023
34499527Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges.Annu Rev Pharmacol Toxicol2022
35771494Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer.Cancer Discov2022
35794066Corrigendum to "A CRISPR screen identifies redox vulnerabilities for KEAP1/NRF2 mutant non-small cell lung cancer" [Redox Biol. 54 (2022) 102358].Redox Biol2022
35667246A CRISPR screen identifies redox vulnerabilities for KEAP1/NRF2 mutant non-small cell lung cancer.Redox Biol2022
35461660Metabolism in tumor-associated macrophages.Int Rev Cell Mol Biol2022
35413105Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer.Cancer Res2022
35922487Long-sought mediator of vitamin K recycling discovered.Nature2022
36379252On the illusion of auxotrophy: met15ο yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w.J Biol Chem2022
36252013Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools.Proc Natl Acad Sci U S A2022
34764459Connecting copper and cancer: from transition metal signalling to metalloplasia.Nat Rev Cancer2022
33037322Establishing a living biobank of patient-derived organoids of intraductal papillary mucinous neoplasms of the pancreas.Lab Invest2021
33664498GSH hoards all the cysteine-what a slimy thing to do.Nat Metab2021
33723873The microbiome(s) and cancer: know thy neighbor(s).J Pathol2021
34725089IL1RAP Pulls a Double Shift in the Cysteine Factory.Cancer Discov2021
34303764Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression.Cancer Lett2021
34127512Metabolic Phenotypes, Dependencies, and Adaptation in Lung Cancer.Cold Spring Harb Perspect Med2021
32482665The Golgi: Keeping It Unapologetically Basic.Cancer Discov2020
31983610Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer.Cancer Cell2020
32007910Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.Redox Biol2020
33080927Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer.Cancers (Basel)2020
32747795The smell of death and deCYStiny: polyamines play the hero.Nat Metab2020
32973367Publisher Correction: The smell of death and deCYStiny: polyamines play the hero.Nat Metab2020
32303435The Complex Interplay between Antioxidants and ROS in Cancer.Trends Cell Biol2020
32196080Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function.J Exp Med2020
31107239Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer.Elife2019
31263025Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer.Cancer Discov2019
31625908Correction: Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer.Elife2019
31451216Sulfur metabolism and its contribution to malignancy.Int Rev Cell Mol Biol2019
31395880Proteogenomic landscape of squamous cell lung cancer.Nat Commun2019
31100816The Non-Essential Amino Acid Cysteine Becomes Essential for Tumor Proliferation and Survival.Cancers (Basel)2019
30799286Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.Cell Metab2019
28899208The Regulation of NRF2 by Nutrient-Responsive Signaling and Its Role in Anabolic Cancer Metabolism.Antioxid Redox Signal2018
29657324Recent advances in cancer metabolism: a technological perspective.Exp Mol Med2018
29232549Stressing Out PanIN: NRF2 Pushes over the Edge.Cancer Cell2017
28443205A pilot study of radiologic measures of abdominal adiposity: weighty contributors to early pancreatic carcinogenesis worth evaluating?Cancer Biol Med2017
27023779Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer.Nat Genet2016
27455510NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages.Nat Med2016
27477511NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.Cell2016
27315299Making sense of reAKTive oxygen species.Cell Death Differ2016
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Collaborators

Nathan P Ward
Moffitt Cancer Center and Research Institute
Co-authored papers 13
Young Pyo Jang
Moffitt Cancer Center and Research Institute
Co-authored papers 10
Lewis C Cantley
Co-authored papers 5
Kristopher K Frese
Cancer Research UK Manchester Institute, University of Manchester
Co-authored papers 4
John D Minna
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 2
Hao Tang
Guizhou Medical University
Co-authored papers 2
David J Adams
Wellcome Sanger Institute
Co-authored papers 2
Jennifer B Permuth
Moffitt Cancer Center
Co-authored papers 2
Yang Xie
Quantitative Biomedical Research Center
Co-authored papers 2
Sang Jun Yoon
Seoul National University
Co-authored papers 2
Jamie K Teer
H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 2
Basetti Madhu
Co-authored papers 2
Jonathan M Buscaglia
Co-authored papers 1
Charlie E Massie
University of Cambridge
Co-authored papers 1
David E Neal
University of Oxford, John Radcliffe Hospital
Co-authored papers 1
Lifu Wang
Co-authored papers 1
Ivan A Belashov
University of Pittsburgh
Co-authored papers 1
Nelson C Coelho
University of Pittsburgh, USA Pittsburgh Center for Evolutionary Biology and Medicine
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William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 1
Aaron Wacholder
University of Pittsburgh
Co-authored papers 1
Costas A Lyssiotis
Co-authored papers 1
Martin E Gleave
University of British Columbia
Co-authored papers 1
Katherine M McCourt
Co-authored papers 1
John M Koomen
Co-authored papers 1
John G Doench
Co-authored papers 1
Ladan Fazli
University of British Columbia
Co-authored papers 1
Luke L Lairson
The Scripps Research Institute
Co-authored papers 1
Anne Y Warren
Cambridge University Hospitals National Health Service Foundation Trust
Co-authored papers 1
Gregory Stephanopoulos
Massachusetts Institute of Technology
Co-authored papers 1
William J Howat
Cancer Research UK Cambridge Institute
Co-authored papers 1
Release 1.2