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Author Details

Andrea Rossi
Pfizer Inc.
2004
46
30
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35911682Investigating the Role of the NLRP3 Inflammasome Pathway in Acute Intestinal Inflammation: Use of THP-1 Knockout Cell Lines in an Advanced Triple Culture Model.Front Immunol2022
29227213Productive common light chain libraries yield diverse panels of high affinity bispecific antibodies.MAbs2018
29714014Epitope Mapping Using Yeast Display and Next Generation Sequencing.Methods Mol Biol2018
28060885Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another.PLoS One2017
27129258Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain.J Biol Chem2016
25284753Precise and efficient antibody epitope determination through library design, yeast display and next-generation sequencing.J Mol Biol2015
25792738Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG.J Biol Chem2015
24862586Transient hyperckemia in the setting of neuromyelitis optica (NMO).Muscle Nerve2014
23197380Inhibition of aquaporin-1 dependent angiogenesis impairs tumour growth in a mouse model of melanoma.J Mol Med (Berl)2013
23690620Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality.Proc Natl Acad Sci U S A2013
23438745Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates.Chem Biol2013
21981006Post-Golgi supramolecular assembly of aquaporin-4 in orthogonal arrays.Traffic2012
22987455Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly.Glia2012
23093611A method for integrative structure determination of protein-protein complexes.Bioinformatics2012
22718347Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes.J Cell Sci2012
22483106Fabs enable single particle cryoEM studies of small proteins.Structure2012
22589299Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica.Proc Natl Acad Sci U S A2012
22294692Increasing serum half-life and extending cholesterol lowering in vivo by engineering antibody with pH-sensitive binding to PCSK9.J Biol Chem2012
22264543Live-cell imaging of aquaporin-4 supramolecular assembly and diffusion.Methods Enzymol2012
22393049Complement-dependent cytotoxicity in neuromyelitis optica requires aquaporin-4 protein assembly in orthogonal arrays.J Biol Chem2012
22019884Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.J Pharmacol Exp Ther2012
22200949Light inactivation of water transport and protein-protein interactions of aquaporin-Killer Red chimeras.J Gen Physiol2012
21212277Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding.J Biol Chem2011
21850708Translational regulation mechanisms of aquaporin-4 supramolecular organization in astrocytes.Glia2011
21952128D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness.Neuroscience2011
21552296Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica.Acta Pharmacol Sin2011
21621278Orthogonal array formation by human aquaporin-4: examination of neuromyelitis optica-associated aquaporin-4 polymorphisms.J Neuroimmunol2011
21689527Model of aquaporin-4 supramolecular assembly in orthogonal arrays based on heterotetrameric association of M1-M23 isoforms.Biophys J2011
21491501Aquaporin-4 Mz isoform: brain expression, supramolecular assembly and neuromyelitis optica antibody binding.Glia2011
21454592Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays.J Biol Chem2011
20007705Evidences for a leaky scanning mechanism for the synthesis of the shorter M23 protein isoform of aquaporin-4: implication in orthogonal array formation and neuromyelitis optica antibody interaction.J Biol Chem2010
20153404Higher order structure of aquaporin-4.Neuroscience2010
19229993Aquaporin-4 orthogonal arrays of particles are the target for neuromyelitis optica autoantibodies.Glia2009
19713739Carbenoxolone inhibits volume-regulated anion conductance in cultured rat cortical astroglia.Channels (Austin)2009
18338794Dystrophin-dependent and -independent AQP4 pools are expressed in the mouse brain.Glia2008
18649401Actin cytoskeleton remodeling governs aquaporin-4 localization in astrocytes.Glia2008
18284610Expression of multiple AQP4 pools in the plasma membrane and their association with the dystrophin complex.J Neurochem2008
17502099The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family.Structure2007
17570147The AnnoLite and AnnoLyze programs for comparative annotation of protein structures.BMC Bioinformatics2007
17478513DBAli tools: mining the protein structure space.Nucleic Acids Res2007
16381869MODBASE: a database of annotated comparative protein structure models and associated resources.Nucleic Acids Res2006
16963645Localization of binding sites in protein structures by optimization of a composite scoring function.Protein Sci2006
15701722Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22.Blood2005
15950230Multiple cathepsin B isoforms in schistosomula of Trichobilharzia regenti: identification, characterisation and putative role in migration and nutrition.Int J Parasitol2005
14681398MODBASE, a database of annotated comparative protein structure models, and associated resources.Nucleic Acids Res2004
15195995Comprehensive search for cysteine cathepsins in the human genome.Biol Chem2004
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Collaborators

University of California San Francisco
Co-authored papers 10
Pfizer Inc.
Co-authored papers 9
Pfizer Inc.
Co-authored papers 8
Pfizer Inc.
Co-authored papers 8
Universitat Pompeu Fabra (UPF)
Co-authored papers 5
Indian Institute of Science Education and Research Pune
Co-authored papers 4
Howard Hughes Medical Institute
Co-authored papers 4
University of California san francisco
Co-authored papers 4
University of California at San Francisco
Co-authored papers 3
School of Chemistry & Pharmaceutical Sciences, Guangxi Normal University
Co-authored papers 3
Spanish National Cancer Research Centre (CNIO)
Co-authored papers 2
Sandler Center for Drug Discovery, University of California San Francisco
Co-authored papers 2
Andalusian Public Foundation Progress and Health-FPS
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Lawrence Berkeley National Laboratory, University of California
Co-authored papers 2
Quantitative Bioscience Institute, University of California san francisco
Co-authored papers 2
University of California san francisco
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Charles University
Co-authored papers 1
Toranomon Hospital
Co-authored papers 1
School of Public Health, University of California berkeley
Co-authored papers 1
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
National Cancer Institute, National Institutes of Health
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Skane University Hospital, Lund University
Co-authored papers 1
Monash University
Co-authored papers 1
Yale University
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Czech University of Life Sciences
Co-authored papers 1
Center for Biomolecular and Cellular Structure, Institute for Basic Science (IBS)
Co-authored papers 1
National Centre for Cell Science, SP Pune University Campus
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