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Author Details

Thomas D Nolin
University of Pittsburgh School of Pharmacy
2002
133
39
PMIDPaper TitleJournal TitlePublished Year
36632215Improved antitumor activity against prostate cancer via synergistic targeting of Myc and GFAT-1.Theranostics2023
37750686Clinical <i>rel</i> mutations in <i>Staphylococcus aureus</i> prime pathogen expansion under nutrient stress.mSphere2023
37348600Electronic health record based population health management to optimize care in CKD: Design of the Kidney Coordinated HeAlth Management Partnership (K-CHAMP) trial.Contemp Clin Trials2023
37252981Scribble scrambles parathyroid hormone receptor interactions to regulate phosphate and vitamin D homeostasis.Proc Natl Acad Sci U S A2023
37042268Limitations of fexofenadine limited sampling strategy using plasma concentrations and partial area under the concentration-time curve to estimate transporter activity in healthy adults.Int J Clin Pharmacol Ther2023
37097973Transdermal Detection of MB-102 and Correlation to Meropenem Pharmacokinetics During Continuous Renal Replacement Therapy: In Vivo Results.ASAIO J2023
37030585Discordance in GFR Estimating Equations and Dosing Guidance by Body Mass Index and Age.Am J Kidney Dis2023
36723359Inclusion of Participants with CKD and Other Kidney-Related Considerations during Clinical Drug Development: Landscape Analysis of Anticancer Agents Approved from 2015 to 2019.Clin J Am Soc Nephrol2023
36645711Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach.Ther Drug Monit2023
34621058Opioids for chronic pain management in patients with dialysis-dependent kidney failure.Nat Rev Nephrol2022
35678297The Impact of Suboptimal 25-Hydroxyvitamin D Levels and Cholecalciferol Replacement on the Pharmacokinetics of Oral Midazolam in Control Subjects and Patients With Chronic Kidney Disease.J Clin Pharmacol2022
35853713Association of Rosuvastatin Use with Risk of Hematuria and Proteinuria.J Am Soc Nephrol2022
35783552Mechanistic Considerations and Pharmacokinetic Implications on Concomitant Drug Administration During CytoSorb Therapy.Crit Care Explor2022
35659658Simultaneous detection of a panel of nine sedatives and metabolites in plasma from critically ill pediatric patients via UPLC-MS/MS.J Pharm Biomed Anal2022
35779863Physiologically Based Pharmacokinetic Modeling of Vitamin D<sub>3</sub> and Metabolites in Vitamin D-Insufficient Patients.Drug Metab Dispos2022
35991694Education Standards for Pharmacists Providing Comprehensive Medication Management in Outpatient Nephrology Settings.Kidney Med2022
35247279Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Impact of Chronic Kidney Disease on CYP3A4-Mediated Metabolism of Saxagliptin.J Clin Pharmacol2022
35236714Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.Clin J Am Soc Nephrol2022
32501620Assessing the effect of extracorporeal treatments for lithium poisoning.Br J Clin Pharmacol2021
35369653New Vancomycin Dosing Guidelines for Hemodialysis Patients: Rationale, Caveats, and Limitations.Kidney3602021
33870862Influence of vitamin D treatment on functional expression of drug disposition pathways in human kidney proximal tubule cells during simulated uremia.Xenobiotica2021
33660266Extracorporeal treatments for isoniazid poisoning: Systematic review and recommendations from the EXTRIP workgroup.Pharmacotherapy2021
34399096Effect of removing race from glomerular filtration rate-estimating equations on anticancer drug dosing and eligibility: a retrospective analysis of National Cancer Institute phase 1 clinical trial participants.Lancet Oncol2021
34358487Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning.Kidney Int2021
33459400Application of Individualized PBPK Modeling of Rate Data to Evaluate the Effect of Hemodialysis on Nonrenal Clearance Pathways.J Clin Pharmacol2021
33276038Risk Factors for Major Hemorrhage Among Patients Receiving Dabigatran Across the Spectrum of CKD Not Requiring Dialysis Therapy.Am J Kidney Dis2021
33078827MCCS: a novel recognition pattern-based method for fast track discovery of anti-SARS-CoV-2 drugs.Brief Bioinform2021
32554707Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease.Sci Transl Med2020
34322673Randomized, Placebo-Controlled Trial of Rifaximin Therapy for Lowering Gut-Derived Cardiovascular Toxins and Inflammation in CKD.Kidney3602020
32089369Hemodialysis removal of caffeine.Am J Emerg Med2020
33205428Dose Optimization in Kidney Disease: Opportunities for PBPK Modeling and Simulation.J Clin Pharmacol2020
32963091Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.J Am Soc Nephrol2020
32611663Adverse Drug Effects in Patients with CKD: <i>Primum Non Nocere</i>.Clin J Am Soc Nephrol2020
30665924Trimethylamine <i>N</i>-Oxide and Cardiovascular Outcomes in Patients with ESKD Receiving Maintenance Hemodialysis.Clin J Am Soc Nephrol2019
31685846Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease.Sci Rep2019
30074626Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Effect of Chronic Kidney Disease on the Disposition of Hepatic CYP2C8 and OATP1B Drug Substrates.Clin Pharmacol Ther2019
31241758Engaging and Empowering Stakeholders to Advance Pharmacogenomics.Clin Pharmacol Ther2019
31399494Simultaneous Assessment of Hepatic Transport and Metabolism Pathways with a Single Probe Using Individualized PBPK Modeling of <sup>14</sup>CO<sub>2</sub> Production Rate Data.J Pharmacol Exp Ther2019
31276982Development and validation of a UHPLC-MS/MS method for measurement of a gut-derived uremic toxin panel in human serum: An application in patients with kidney disease.J Pharm Biomed Anal2019
30890575Estimation of Kidney Function in Oncology: Implications for Anticancer Drug Selection and Dosing.Clin J Am Soc Nephrol2019
30307333Extracorporeal treatment in salicylate poisoning.Clin Toxicol (Phila)2019
28905671Microbiota-derived uremic retention solutes: perpetrators of altered nonrenal drug clearance in kidney disease.Expert Rev Clin Pharmacol2018
29915157Decreased Kidney Function Is Associated with Enhanced Hepatic Flavin Monooxygenase Activity and Increased Circulating Trimethylamine <i>N</i>-Oxide Concentrations in Mice.Drug Metab Dispos2018
29958694Use of extracorporeal treatments in the management of poisonings.Kidney Int2018
30283097Gut Colonization with Methanogenic Archaea Lowers Plasma Trimethylamine N-oxide Concentrations in Apolipoprotein e-/- Mice.Sci Rep2018
29499882Pragmatic Use of Kidney Function Estimates for Drug Dosing: The Tide Is Turning.Adv Chronic Kidney Dis2018
29661769Introduction to Nephropharmacology for the Clinician: A New <i>CJASN</i> Series.Clin J Am Soc Nephrol2018
28990182Effect of Chronic Kidney Disease on Nonrenal Elimination Pathways: A Systematic Assessment of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and OATP.Clin Pharmacol Ther2018
29329421Beta-2 microglobulin clearance in high-flux dialysis and convective dialysis modalities: a meta-analysis of published studies.Nephrol Dial Transplant2018
29351922Activation of Constitutive Androstane Receptor Ameliorates Renal Ischemia-Reperfusion-Induced Kidney and Liver Injury.Mol Pharmacol2018
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Collaborators

Jonathan Himmelfarb
Kidney Research Institute and Division of Nephrology, University of Washington
Co-authored papers 8
Mark Unruh
Co-authored papers 7
Kathleen D Liu
University of California san francisco
Co-authored papers 6
Stuart L Goldstein
Cincinnati Children's Hospital Medical Center, University of Cincinnati
Co-authored papers 3
Samuel M Poloyac
University of Texas
Co-authored papers 3
William H Fissell
Vanderbilt University Medical Center
Co-authored papers 3
David J Askenazi
University of Alabama Birmingham
Co-authored papers 2
Jos??e Bouchard
Sacre-Coeur Hospital
Co-authored papers 2
Alan S L Yu
The Jared Grantham Kidney Institute, University of Kansas Medical Center
Co-authored papers 2
Bradley L Urquhart
Schulich School of Medicine and Dentistry, Western University
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Robert S B Clark
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
Co-authored papers 2
Nita A Limdi
Heersink School of Medicine, University of Alabama at Birmingham
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Benjamin D Humphreys
Washington University in St. Louis School of Medicine
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Patrick M Kochanek
University of Pittsburgh School of Medicine
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Mary F Paine
Washington State University
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Michael J Bell
Children's National Hospital, George Washington University School of Medicine
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Jorge Cerda
Albany Medical College
Co-authored papers 2
Timothy E Bunchman
Children's Hospital of Richmond
Co-authored papers 2
Girish Mour
Mayo Clinic Arizona
Co-authored papers 2
Anitha Vijayan
Washington University in St. Louis.
Co-authored papers 2
Manisha Jhamb
University of Pittsburgh School of Medicine
Co-authored papers 2
Sarah Faubel
University of Colorado School of Medicine
Co-authored papers 2
Morgan E Grams
New York University Grossman School of Medicine
Co-authored papers 2
Timothy M Beasley
School of Public Health, University of Alabama at Birmingham
Co-authored papers 2
Bedda L Rosario
University of Pittsburgh
Co-authored papers 1
George Caleb Alexander
Institute of General Practice and Family Medicine, University Hospital
Co-authored papers 1
Tripti Singh
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Jay L Koyner
University of Chicago, Pritzker School of Medicine
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Azra Bihorac
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Release 1.2