Author details

Full Name

Sarah Edkins

Affiliation

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36972964	Immune and metabolic markers for identifying and investigating severe Coronavirus disease and Sepsis in children and young people (pSeP/COVID ChYP study): protocol for a prospective cohort study.	BMJ Open	2023
36115679	mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health - a prospective observational cohort study protocol.	BMJ Open	2022
33108352	Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.	Journal of Clinical Investigation	2021
37010923	nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis-protocol for a prospective multicohort study.	BMJ Open	2021
33266331	Distinctive Features of Orbital Adipose Tissue (OAT) in Graves' Orbitopathy.	International Journal of Molecular Sciences	2020
31378673	Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia.	Stem Cell Reports	2019
28566273	An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.	Diabetes	2017
27618452	The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.	Nat Genet	2016
27236921	Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.	Am J Hum Genet	2016
26551672	Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.	Nat Genet	2015
25003214	The correlation between reading and mathematics ability at age twelve has a substantial genetic component.	Nat Commun	2014
23871474	A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.	Biol Psychiatry	2014
24509480	Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.	Nat Genet	2014
23717212	Imputation-based meta-analysis of severe malaria in three African populations.	PLoS Genet	2013
24046328	A variant in LDLR is associated with abdominal aortic aneurysm.	Circ Cardiovasc Genet	2013
24076602	Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.	Nat Genet	2013
23974872	Genome-wide association analysis identifies 13 new risk loci for schizophrenia.	Nat Genet	2013
23754948	Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.	PLoS Genet	2013
23603761	Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.	Nat Genet	2013
23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Nat Genet	2013
23291585	Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.	Nat Genet	2013
23143594	Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.	Nat Genet	2012
22306652	Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.	Nat Genet	2012
22885924	Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.	Nat Genet	2012
22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Nat Genet	2012
22961001	Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.	Nat Genet	2012
23143596	High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.	Nat Genet	2012
22055160	Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.	Am J Hum Genet	2011
21044948	Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.	Hum Mol Genet	2011
21186350	Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.	Nat Genet	2011
22200769	Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.	Nat Genet	2011
21833088	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	Nature	2011
22057235	Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.	Nat Genet	2011
22069447	An evaluation of different target enrichment methods in pooled sequencing designs for complex disease association studies.	PLoS One	2011
20016485	A comprehensive catalogue of somatic mutations from a human cancer genome.	Nature	2010
20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Nat Genet	2010
19837654	PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data.	Biostatistics	2010
20164919	Signatures of mutation and selection in the cancer genome.	Nature	2010
19826449	Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype-phenotype correlation.	Eur J Hum Genet	2010
20544845	GLO1-A novel amplified gene in human cancer.	Genes Chromosomes Cancer	2010
20054297	Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.	Nature	2010
20360734	Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.	Nature	2010
20016488	A small-cell lung cancer genome with complex signatures of tobacco exposure.	Nature	2010
19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Nat Genet	2009
19165201	LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition.	Br J Cancer	2009
19377476	A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.	Nat Genet	2009
19330029	Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.	Nat Genet	2009
20033038	Complex landscapes of somatic rearrangement in human breast cancer genomes.	Nature	2009
18455129	Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation.	Am J Hum Genet	2008
18438408	Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.	Nat Genet	2008