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Author Details

Philippa J Talmud
University of Bristol
1974
282
70
PMIDPaper TitleJournal TitlePublished Year
29440116Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.Circ Genom Precis Med2018
28770004Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.BioData Min2017
25979724Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.Int J Epidemiol2016
27365493Marginal role for 53 common genetic variants in cardiovascular disease prediction.Heart2016
27532233Genetically determined telomeres shortening is associated with carotid atherosclerosis progression and increased incidence of cardiovascular events.Int J Cardiol2016
27180643Corrigendum to "APOA5 variants predispose hyperlipidemic patients to atherogenic dyslipidemia and subclinical atherosclerosis" [Atherosclerosis 240/1 (2015) 98-104].Atherosclerosis2016
26800306Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3.Atherosclerosis2016
26790392D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile.Nat Commun2016
26781229Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.Lancet Diabetes Endocrinol2016
24474739Mendelian randomization of blood lipids for coronary heart disease.Eur Heart J2015
26338298Deciphering the Causal Role of sPLA2s and Lp-PLA2 in Coronary Heart Disease.Arterioscler Thromb Vasc Biol2015
25962519Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.Nat Commun2015
25974167Effect of the PPARG2 Pro12Ala Polymorphism on Associations of Physical Activity and Sedentary Time with Markers of Insulin Sensitivity in Those with an Elevated Risk of Type 2 Diabetes.PLoS One2015
25692342Identifying functional noncoding variants from genome-wide association studies for cardiovascular disease and related traits.Curr Opin Lipidol2015
25811611Demonstration of the presence of the "deleted" MIR122 gene in HepG2 cells.PLoS One2015
25770687APOA5 variants predispose hyperlipidemic patients to atherogenic dyslipidemia and subclinical atherosclerosis.Atherosclerosis2015
25475436Sixty-five common genetic variants and prediction of type 2 diabetes.Diabetes2015
25414277Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries.Clin Chem2015
25583995PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk.Circ Cardiovasc Genet2015
25262344HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.Lancet2015
25040775Telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general population.J Intern Med2015
24315920Reply: limits of Mendelian randomization analyses in selection of secretory phospholipase A2-IIA as a valid therapeutic target for prevention of cardiovascular disease.J Am Coll Cardiol2014
25225788A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.Nat Commun2014
25011450Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.BMJ2014
24977977The genetic architecture of the familial hyperlipidaemia syndromes: rare mutations and common variants in multiple genes.Curr Opin Lipidol2014
25173947A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease.Atherosclerosis2014
24563418Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels.Circ Cardiovasc Genet2014
22977227Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.Eur Heart J2013
24349443Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.PLoS One2013
24121499Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets.J Biol Chem2013
24178511Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.Thromb Haemost2013
23916927Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.J Am Coll Cardiol2013
23977022Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.PLoS One2013
23433573Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.Lancet2013
23535734Identification of seven loci affecting mean telomere length and their association with disease.Nat Genet2013
23505291Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.Circ Cardiovasc Genet2013
23569189Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.Int J Epidemiol2013
23541341The benefits of using genetic information to design prevention trials.Am J Hum Genet2013
23161678Gene Ontology annotations and resources.Nucleic Acids Res2013
23246012A gene-centric study of common carotid artery remodelling.Atherosclerosis2013
23275344Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.Circ Cardiovasc Genet2013
21444365Association of a sequence variant in DAB2IP with coronary heart disease.Eur Heart J2012
23018754Genetic analysis of NR0B1 in congenital adrenal hypoplasia patients: identification of a rare regulatory variant resulting in congenital adrenal hypoplasia and hypogonadal hypogonadism without testicular carcinoma in situ.Sex Dev2012
23139254Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.Circ Cardiovasc Genet2012
23152477Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk.Circ Cardiovasc Genet2012
23064415A common single-nucleotide variant in T is strongly associated with chordoma.Nat Genet2012
23063622Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.Am J Hum Genet2012
22916038Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays.PLoS Genet2012
22879865Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels.PLoS One2012
22421340The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.Lancet2012
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