Author details

Full Name

Kyoung-Jae Won

Affiliation

ORCID

Career Start Year

2004

Papers

106

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36781874	Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice.		2023
37431867	Phenylpropionic acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity.		2023
37225426	Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis.		2023
35166670	Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models.	Elife	2022
35708349	A PDX1 cistrome and single-cell transcriptome resource of the developing pancreas.	Development (Cambridge)	2022
35444258	Dormant state of quiescent neural stem cells links Shank3 mutation to autism development.	Molecular Psychiatry	2022
36214625	Cell Competition in Carcinogenesis.	Cancer Res	2022
35801910	Systemic approaches using single cell transcriptome reveal that C/EBPÎ³ regulates autophagy under amino acid starved condition.	Nucleic Acids Research	2022
36065846	Vesalius: high-resolution in silico anatomization of spatial transcriptomic data using image analysis.	Molecular Systems Biology	2022
35719864	Cardiac fibroblast sub-types <i>in vitro</i> reflect pathological cardiac remodeling <i>in vivo</i>.	Matrix Biol Plus	2022
34368984	Cell competition in intratumoral and tumor microenvironment interactions.	EMBO Journal	2021
34016130	Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer.	Journal of Experimental and Clinical Cancer Research	2021
34134142	Decreased KATP Channel Activity Contributes to the Low Glucose Threshold for Insulin Secretion of Rat Neonatal Islets.	Endocrinology	2021
33974009	VeTra: a tool for trajectory inference based on RNA velocity.		2021
33497421	A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism.	PLoS Pathog	2021
33495631	Basement membrane stiffness determines metastases formation.	Nature Materials	2021
33299144	Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy.	Leukemia	2021
33170214	TENET: gene network reconstruction using transfer entropy reveals key regulatory factors from single cell transcriptomic data.	Nucleic Acids Research	2021
34467975	The Transcriptome and Epigenome Reveal Novel Changes in Transcription Regulation During Pancreatic Rat Islet Maturation.	Endocrinology	2021
34661368	Flower lose, a cell fitness marker, predicts COVID-19 prognosis.	EMBO Mol Med	2021
33053583	Transcriptomic and Quantitative Proteomic Profiling Reveals Signaling Pathways Critical for Pancreatic Islet Maturation.	Endocrinology	2020
31992615	SHARP: hyperfast and accurate processing of single-cell RNA-seq data via ensemble random projection.	Genome Research	2020
32212902	A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.	Circ Res	2020
33293536	Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy.	Nature Communications	2020
32507771	Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology.	Molecules and Cells	2020
30709899	Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid.	Journal of Lipid Research	2019
32821705	Single Cell RNA-Sequencing for the Study of Atherosclerosis.	Journal of Lipid and Atherosclerosis	2019
30598508	Commensal Gut Bacteria Convert the Immunosuppressant Tacrolimus to Less Potent Metabolites.	Drug Metabolism and Disposition	2019
30373755	A Family of Small Intrinsically Disordered Proteins Involved in Flagellum-Dependent Motility in Salmonella enterica.	Journal of Bacteriology	2019
31287806	MondoA drives muscle lipid accumulation and insulin resistance.	JCI Insight	2019
31488567	Genomic architecture of Shh-dependent cochlear morphogenesis.	Development (Cambridge)	2019
31043436	Characterization of Vitamin A Metabolome in Human Livers With and Without Nonalcoholic Fatty Liver Disease.	Journal of Pharmacology and Experimental Therapeutics	2019
29439026	Rev-erbÎ± dynamically modulates chromatin looping to control circadian gene transcription.	Science	2018
30102368	CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.	Nucleic Acids Research	2018
30085281	Shared nucleotide flanks confer transcriptional competency to bZip core motifs.	Nucleic Acids Research	2018
29402210	Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus.	BMC Bioinformatics	2018
29309562	Transcriptomic Analysis Reveals Novel Mechanisms Mediating Islet Dysfunction in the Intrauterine Growth-Restricted Rat.	Endocrinology	2018
29760084	Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue.	Proc Natl Acad Sci U S A	2018
29395062	PKCÎ±-LSD1-NF-ÎºB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response.	Mol Cell	2018
28079882	Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.	Cell Death and Disease	2017
28428261	EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex.	Genes and Development	2017
28408438	PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.	EMBO Journal	2017
28366641	Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts.	Molecular Cell	2017
28614293	Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.	Nature	2017
28779374	DNA hypermethylation induced by Epstein-Barr virus in the development of Epstein-Barr virus-associated gastric carcinoma.	Archives of Pharmacal Research	2017
28011883	Single cell transcriptomic profiling of mouse pancreatic progenitors.	Physiological Genomics	2017
27941246	LIM domain-binding 1 maintains the terminally differentiated state of pancreatic Î² cells.	J Clin Invest	2017
28240605	Targeting PPARÎ³ in the epigenome rescues genetic metabolic defects in mice.	Journal of Clinical Investigation	2017
28153841	Cholic Acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice.	Drug Metabolism and Disposition	2017
27856615	Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation.	Genes Dev	2016