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Author Details

Lee Murphy
Edinburgh Clinical Research Facility, University of Edinburgh
1998
55
33
PMIDPaper TitleJournal TitlePublished Year
36855161Refining epigenetic prediction of chronological and biological age.Genome Med2023
37548242Cellular heterogeneity of the developing worker honey bee (Apis mellifera) pupa: a single cell transcriptomics analysis.G3 (Bethesda)2023
38053194Integration of datasets for individual prediction of DNA methylation-based biomarkers.Genome Biol2023
36948324Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders.Brain Behav Immun2023
37117793Development and validation of DNA methylation scores in two European cohorts augment 10-year risk prediction of type 2 diabetes.Nat Aging2023
37410739Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based linked cohort study of 18,413 Scottish individuals.PLoS Med2023
37235648CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages.Sci Adv2023
36210800Feasibility and ethics of using data from the Scottish newborn blood spot archive for research.Commun Med (Lond)2022
35402911DNA methylation in relation to gestational age and brain dysmaturation in preterm infants.Brain Commun2022
35788175Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.Nat Med2022
35362642A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens.Eur J Neurosci2022
33307546Genetic mechanisms of critical illness in COVID-19.Nature2021
33514701De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands.Nat Commun2021
33785425Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.Mol Metab2021
32450543Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936.Stem Cell Res2020
31992186Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: comparison of gene expression profiling approaches.BMC Bioinformatics2020
30984878Assessment of dried blood spots for DNA methylation profiling.Wellcome Open Res2019
31325907Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies.Eur J Endocrinol2019
30514905Identification of 55,000 Replicated DNA Methylation QTL.Sci Rep2018
29207374Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.Aging (Albany NY)2017
28095459Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.PLoS Med2017
25617346The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936.Int J Epidemiol2015
26354815Utility of Whole-Genome Sequencing of Escherichia coli O157 for Outbreak Detection and Epidemiological Surveillance.J Clin Microbiol2015
25985418DNA immunoprecipitation semiconductor sequencing (DIP-SC-seq) as a rapid method to generate genome wide epigenetic signatures.Sci Rep2015
25633388DNA methylation age of blood predicts all-cause mortality in later life.Genome Biol2015
25249537Genetic and environmental exposures constrain epigenetic drift over the human life course.Genome Res2014
23521772Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study.BMC Med Genet2013
22306652Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.Nat Genet2012
19432983Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens.Genome Biol2009
18419807The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.Genome Biol2008
17572675Comparative genomic analysis of three Leishmania species that cause diverse human disease.Nat Genet2007
16532061Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes.PLoS Genet2006
16902086Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii.Genome Res2006
16885469Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction.J Bacteriol2006
16020728The genome of the kinetoplastid parasite, Leishmania major.Science2005
16120809Evidence for a dispersed Hox gene cluster in the platyhelminth parasite Schistosoma mansoni.Mol Biol Evol2005
15965256Gene arrays at Pneumocystis carinii telomeres.Genetics2005
15994557Genome of the host-cell transforming parasite Theileria annulata compared with T. parva.Science2005
14998527Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster.Fungal Genet Biol2004
15009889SCP1, a 356,023 bp linear plasmid adapted to the ecology and developmental biology of its host, Streptomyces coelicolor A3(2).Mol Microbiol2004
15003838Gene synteny and evolution of genome architecture in trypanosomatids.Mol Biochem Parasitol2004
12606174Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei.Lancet2003
12910271Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.Nat Genet2003
11751581Mapping and identification of essential gene functions on the X chromosome of Drosophila.EMBO Rep2002
12324359Complete sequence and organization of pBtoxis, the toxin-coding plasmid of Bacillus thuringiensis subsp. israelensis.Appl Environ Microbiol2002
12368867Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.Nature2002
12000953Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).Nature2002
11462837Sequencing bacterial artificial chromosomes.Methods Mol Biol2001
11234002Massive gene decay in the leprosy bacillus.Nature2001
11337470From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies.Genome Res2001
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Collaborators

Wellcome Trust Sanger Institute
Co-authored papers 19
Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 15
Wellcome Sanger Institute
Co-authored papers 6
Earlham Institute
Co-authored papers 6
Co-authored papers 5
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Institute of Molecular Bioscience, The University of Queensland
Co-authored papers 5
Institute of Molecular Biology and Biotechnology
Co-authored papers 4
University of Florida
Co-authored papers 4
Universidad Autonoma de Madrid
Co-authored papers 4
CNRS, University of Rennes 1
Co-authored papers 4
INSERM U-, CNRS
Co-authored papers 4
University of Washington School of Medicine
Co-authored papers 4
Wellcome Trust Sanger Institute
Co-authored papers 4
Co-authored papers 4
Co-authored papers 4
University of Cambridge
Co-authored papers 4
Co-authored papers 3
King Abdullah University of Science and Technology
Co-authored papers 3
Co-authored papers 3
The Open University
Co-authored papers 3
University of Cambridge
Co-authored papers 3
University of Guelph
Co-authored papers 2
The Wellcome Trust Sanger Institute
Co-authored papers 2
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Illumina Ltd.
Co-authored papers 2
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Malawi-Liverpool-Wellcome Trust Clinical Research Program
Co-authored papers 2
Weatherall Institute of Molecular Medicine
Co-authored papers 2