Author details

Full Name

Vinodh N Rajapakse

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36715552	Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.	Cancer Discov	2023
37343696	Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets.	Mol Cell Proteomics	2023
36381660	Replication stress defines distinct molecular subtypes across cancers.	Cancer Res Commun	2022
35440132	Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models.	Nat Commun	2022
33196823	CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics.	Nucleic Acids Res	2021
32474729	Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seq.	Virchows Arch	2021
33848478	Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.	Cancer Cell	2021
34045232	Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents.	Mol Cancer Ther	2021
33504652	Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies.	Sci Transl Med	2021
32832595	Phenotype stability under dynamic brain-tumor environment stimuli maps glioblastoma progression in patients.	Science advances	2020
32464188	Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers: Results From a Retrospective Multicenter Cohort Study.	Chest	2020
33086069	SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures.	Cell Rep	2020
33028646	Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair-deficient tumors.	Cold Spring Harb Mol Case Stud	2020
31632920	Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.	Front Oncol	2019
31733513	Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.	iScience	2019
29391350	Overcoming Resistance to DNA-Targeted Agents by Epigenetic Activation of Schlafen 11 (<i>SLFN11)</i> Expression with Class I Histone Deacetylase Inhibitors.	Clin Cancer Res	2018
30553813	CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines.	iScience	2018
29719618	ONC201 kills breast cancer cells <i>in vitro</i> by targeting mitochondria.	Oncotarget	2018
29395061	SLFN11 Blocks Stressed Replication Forks Independently of ATR.	Mol Cell	2018
28159862	Temozolomide in the Era of Precision Medicine.	Cancer Res	2017
28993637	HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia.	Sci Rep	2017
28802254	TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.	Mol Cancer Ther	2017
27923837	The NCI-60 Methylome and Its Integration into CellMiner.	Cancer Res	2017
27601591	Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer.	Clin Cancer Res	2017
26635141	rcellminer: exploring molecular profiles and drug response of the NCI-60 cell lines in R.	Bioinformatics	2016
26876487	The histone variant H2A.X is a regulator of the epithelial-mesenchymal transition.	Nat Commun	2016
25213708	Using drug response data to identify molecular effectors, and molecular "omic" data to identify candidate drugs in cancer.	Hum Genet	2015
25779942	SLFN11 Is a Transcriptional Target of EWS-FLI1 and a Determinant of Drug Response in Ewing Sarcoma.	Clin Cancer Res	2015
25758781	Alterations of DNA repair genes in the NCI-60 cell lines and their predictive value for anticancer drug activity.	DNA Repair (Amst)	2015
21554761	Nonlinear gene cluster analysis with labeling for microarray gene expression data in organ development.	BMC Proceedings	2011
21310028	RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis.	BMC Bioinformatics	2011
15947101	Low molecular weight proteomic information distinguishes metastatic from benign pheochromocytoma.	Endocr Relat Cancer	2005
15751091	A serum proteomic approach to gauging the state of remission in Wegener's granulomatosis.	Arthritis Rheum	2005
15163296	High-resolution serum proteomic features for ovarian cancer detection.	Endocr Relat Cancer	2004
14706336	Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.	Cancer Cell	2003