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Author Details
Full Name
Lewyn Li
Affiliation
Dana-Farber Cancer Institute, Harvard Medical School
ORCID
Career Start Year
2000
Papers
30
H Index
24
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
32690948
Prostate cancer reactivates developmental epigenomic programs during metastatic progression.
Nat Genet
2020
30996345
LLGL2 rescues nutrient stress by promoting leucine uptake in ER<sup>+</sup> breast cancer.
Nature
2019
31307004
Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer.
iScience
2019
31110002
Estrogen receptor signaling is reprogrammed during breast tumorigenesis.
Proc Natl Acad Sci U S A
2019
27111282
Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles.
Nat Med
2016
27716038
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline.
BMC Bioinformatics
2016
27312177
Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer.
Cancer Discov
2016
26051943
Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.
Cell Rep
2015
24154738
In vivo emergence of a novel mutant L159F/L320F in the NS5B polymerase confers low-level resistance to the HCV polymerase inhibitors mericitabine and sofosbuvir.
J Infect Dis
2014
25140696
Similar prevalence of low-abundance drug-resistant variants in treatment-naive patients with genotype 1a and 1b hepatitis C virus infections as determined by ultradeep pyrosequencing.
PLoS One
2014
24637689
Identification of the NS5B S282T resistant variant and two novel amino acid substitutions that affect replication capacity in hepatitis C virus-infected patients treated with mericitabine and danoprevir.
Antimicrob Agents Chemother
2014
22558093
Transcriptome profiling of the intoxication response of Tenebrio molitor larvae to Bacillus thuringiensis Cry3Aa protoxin.
PLoS One
2012
21347285
The genome sequence of the leaf-cutter ant Atta cephalotes reveals insights into its obligate symbiotic lifestyle.
PLoS Genet
2011
21967120
Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes).
BMC Genomics
2011
20413674
Complete mitochondrial genome phylogeographic analysis of killer whales (Orcinus orca) indicates multiple species.
Genome Res
2010
20885794
An insect herbivore microbiome with high plant biomass-degrading capacity.
PLoS Genet
2010
18688485
High sensitivity to transmission of attenuation in the metal activating effect of platinum on sequential H-D exchange at the four C8 sites of inosines in tetrakis(inosine)platinum(II) chloride.
Org Biomol Chem
2008
17028145
Contour length and refolding rate of a small protein controlled by engineered disulfide bonds.
Biophys J
2007
16387766
Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy.
Biophys J
2006
16782796
Fingerprinting DHFR in single-molecule AFM studies.
Biophys J
2006
15588828
Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module.
J Mol Biol
2005
16100277
Ligand binding modulates the mechanical stability of dihydrofolate reductase.
Biophys J
2005
16106519
Using ethics to fight bioterrorism.
Science
2005
12679523
Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases.
Proc Natl Acad Sci U S A
2003
12084924
Topological determinants of protein folding.
Proc Natl Acad Sci U S A
2002
11178898
Different circular permutations produced different folding nuclei in proteins: a computational study.
J Mol Biol
2001
11606790
Constructing, verifying, and dissecting the folding transition state of chymotrypsin inhibitor 2 with all-atom simulations.
Proc Natl Acad Sci U S A
2001
10742180
Kinetics, thermodynamics and evolution of non-native interactions in a protein folding nucleus.
Nat Struct Biol
2000
11071813
Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction.
J Mol Biol
2000
11011702
Relating helix tilt in a bilayer to lipid disorder: a mean-field theory.
Biophys Chem
2000
1 - 30 of 30
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Great Lakes Bioenergy Research Center, the University of Wisconsin-Madison
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Co-authored papers
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Broad Institute of MIT and Harvard
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Johns Hopkins University
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National Cancer Institute
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Harvard Medical School
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