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Author Details

Lewyn Li
Dana-Farber Cancer Institute, Harvard Medical School
2000
30
24
PMIDPaper TitleJournal TitlePublished Year
32690948Prostate cancer reactivates developmental epigenomic programs during metastatic progression.Nat Genet2020
30996345LLGL2 rescues nutrient stress by promoting leucine uptake in ER<sup>+</sup> breast cancer.Nature2019
31307004Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer.iScience2019
31110002Estrogen receptor signaling is reprogrammed during breast tumorigenesis.Proc Natl Acad Sci U S A2019
27111282Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles.Nat Med2016
27716038ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline.BMC Bioinformatics2016
27312177Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer.Cancer Discov2016
26051943Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.Cell Rep2015
24154738In vivo emergence of a novel mutant L159F/L320F in the NS5B polymerase confers low-level resistance to the HCV polymerase inhibitors mericitabine and sofosbuvir.J Infect Dis2014
25140696Similar prevalence of low-abundance drug-resistant variants in treatment-naive patients with genotype 1a and 1b hepatitis C virus infections as determined by ultradeep pyrosequencing.PLoS One2014
24637689Identification of the NS5B S282T resistant variant and two novel amino acid substitutions that affect replication capacity in hepatitis C virus-infected patients treated with mericitabine and danoprevir.Antimicrob Agents Chemother2014
22558093Transcriptome profiling of the intoxication response of Tenebrio molitor larvae to Bacillus thuringiensis Cry3Aa protoxin.PLoS One2012
21347285The genome sequence of the leaf-cutter ant Atta cephalotes reveals insights into its obligate symbiotic lifestyle.PLoS Genet2011
21967120Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes).BMC Genomics2011
20413674Complete mitochondrial genome phylogeographic analysis of killer whales (Orcinus orca) indicates multiple species.Genome Res2010
20885794An insect herbivore microbiome with high plant biomass-degrading capacity.PLoS Genet2010
18688485High sensitivity to transmission of attenuation in the metal activating effect of platinum on sequential H-D exchange at the four C8 sites of inosines in tetrakis(inosine)platinum(II) chloride.Org Biomol Chem2008
17028145Contour length and refolding rate of a small protein controlled by engineered disulfide bonds.Biophys J2007
16387766Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy.Biophys J2006
16782796Fingerprinting DHFR in single-molecule AFM studies.Biophys J2006
15588828Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module.J Mol Biol2005
16100277Ligand binding modulates the mechanical stability of dihydrofolate reductase.Biophys J2005
16106519Using ethics to fight bioterrorism.Science2005
12679523Amino acids determining enzyme-substrate specificity in prokaryotic and eukaryotic protein kinases.Proc Natl Acad Sci U S A2003
12084924Topological determinants of protein folding.Proc Natl Acad Sci U S A2002
11178898Different circular permutations produced different folding nuclei in proteins: a computational study.J Mol Biol2001
11606790Constructing, verifying, and dissecting the folding transition state of chymotrypsin inhibitor 2 with all-atom simulations.Proc Natl Acad Sci U S A2001
10742180Kinetics, thermodynamics and evolution of non-native interactions in a protein folding nucleus.Nat Struct Biol2000
11071813Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction.J Mol Biol2000
11011702Relating helix tilt in a bilayer to lipid disorder: a mean-field theory.Biophys Chem2000
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Collaborators

Harvard University
Co-authored papers 6
Co-authored papers 5
Regeneron Pharmaceuticals, Inc.
Co-authored papers 4
NVIDIA Corporation
Co-authored papers 3
University of Wisconsin-Madison
Co-authored papers 2
University of Wisconsin - Madison
Co-authored papers 2
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Cedars-Sinai Medical Center
Co-authored papers 2
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Co-authored papers 2
Smithsonian Tropical Research Institute
Co-authored papers 2
Dana-Farber Cancer Institute
Co-authored papers 2
Great Lakes Bioenergy Research Center, the University of Wisconsin-Madison
Co-authored papers 2
Co-authored papers 2
Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
University of Hawaii at Hilo
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1
National Cancer Institute
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 1
Wellcome Sanger Institute
Co-authored papers 1
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 1
Institute for Integrative Systems Biology, Spanish National Research Council (CSIC)
Co-authored papers 1
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Garvan Institute of Medical Research
Co-authored papers 1
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Oklahoma State University
Co-authored papers 1