Author details

Full Name

Scott H Randell

Affiliation

ORCID

Career Start Year

1985

Papers

231

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36594405	Evaluation of chronic cigarette smoke exposure in human bronchial epithelial cultures.		2023
37756379	A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.	Sci Transl Med	2023
37749254	Host range, transmissibility and antigenicity of a pangolin coronavirus.	Nat Microbiol	2023
38016030	Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis (NCFB).		2023
37625411	Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells.		2023
37285404	Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.		2023
37196698	Air-Liquid interface cultures to model drug delivery through the mucociliary epithelial barrier.		2023
36563691	An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2.	Cell Host Microbe	2023
36796082	A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease.	Am J Respir Crit Care Med	2023
35132416	Visible blue light inactivates SARS-CoV-2 variants and inhibits Delta replication in differentiated human airway epithelia.		2022
35906215	A multimodal iPSC platform for cystic fibrosis drug testing.	Nature Communications	2022
35900863	Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough.	Journal of Clinical Investigation	2022
35577980	TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice.	Oncogene	2022
35816430	Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.	Am J Respir Crit Care Med	2022
36002660	Correction: TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice.	Oncogene	2022
35363522	Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis.	Science advances	2022
35355018	Human distal lung maps and lineage hierarchies reveal a bipotent progenitor.	Nature	2022
36414761	Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging.	Nat Methods	2022
36316562	Unsupervised discovery of tissue architecture in multiplexed imaging.	Nat Methods	2022
33794364	Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus.	Mol Ther	2022
34049825	Epigenome editing of the CFTR-locus for treatment of cystic fibrosis.	Journal of Cystic Fibrosis	2022
35040594	Pharmacokinetic-based failure of a detergent virucidal for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) nasal infections: A preclinical study and randomized controlled trial.	Int Forum Allergy Rhinol	2022
34372702	Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury.	mBio	2021
34013253	Pharmacokinetic-based failure of a detergent virucidal for SARS-COV-2 nasal infections.	Res Sq	2021
33958799	Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition.	Nature Medicine	2021
33534640	DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy.	Molecular Biology of the Cell	2021
33788674	Chromatin Landscapes of Human Lung Cells Predict Potentially Functional Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Variants.	Am J Respir Cell Mol Biol	2021
33788673	Reuse of Cell Culture Inserts for Human Primary Airway Epithelial Cell Studies.	American Journal of Respiratory Cell and Molecular Biology	2021
34107015	Enhanced delivery of peptide-morpholino oligonucleotides with a small molecule to correct splicing defects in the lung.	Nucleic Acids Res	2021
33831321	The Big Impact of Small Airway pH.	American Journal of Respiratory Cell and Molecular Biology	2021
34326365	Somatic cell hemoglobin modulates nitrogen oxide metabolism in the human airway epithelium.	Scientific Reports	2021
33321047	Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia.	American Journal of Respiratory and Critical Care Medicine	2021
34546976	Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness.	JCI insight	2021
32661400	Author Correction: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.	Nat Med	2020
31969610	Mechanical forces induce an asthma gene signature in healthy airway epithelial cells.	Sci Rep	2020
31801868	Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.	J Virol	2020
32402246	Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction.	Molecular Therapy	2020
32437238	Assessing Human Airway Epithelial Progenitor Cells for Cystic Fibrosis Cell Therapy.	American Journal of Respiratory Cell and Molecular Biology	2020
33046644	Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection.	Proc Natl Acad Sci U S A	2020
32601108	Human Fallopian Tube Epithelial Cell Culture Model To Study Host Responses to Chlamydia trachomatis Infection.	Infection and Immunity	2020
32593509	Fibrocyte accumulation in the lungs of cystic fibrosis patients.	Journal of Cystic Fibrosis	2020
32978168	A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking.	Cancer Res	2020
32526206	SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.	Cell	2020
32692579	Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs.	American Journal of Respiratory and Critical Care Medicine	2020
33184236	SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo.	Science	2020
33128895	Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.	Cell Stem Cell	2020
33024969	SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo.	bioRxiv	2020
32741223	Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis.	Human Gene Therapy	2020
32619021	A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.	J Pathol	2020
32559455	Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patients.	Lung Cancer	2020