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Author Details

Laurie Ailles
University of Toronto
1991
89
36
PMIDPaper TitleJournal TitlePublished Year
36253570PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.Nat Rev Urol2023
375589513D Spheroid Invasion Assay for High-Throughput Screening of Small-Molecule Libraries.Methods Mol Biol2023
352317863D microgels to quantify tumor cell properties and therapy response dynamics.Biomaterials2022
36428645Extracellular Heparan 6-<i>O</i>-Endosulfatases SULF1 and SULF2 in Head and Neck Squamous Cell Carcinoma and Other Malignancies.Cancers (Basel)2022
36671461Proteomics of High-Grade Serous Ovarian Cancer Models Identifies Cancer-Associated Fibroblast Markers Associated with Clinical Outcomes.Biomolecules2022
36206767Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas.Mol Cell2022
35238880Development and Validation of an Oral Cavity Cancer Outcomes Prediction Score Incorporating Patient-Derived Xenograft Engraftment.JAMA Otolaryngol Head Neck Surg2022
35205707Modeling the Role of Cancer-Associated Fibroblasts in Tumor Cell Invasion.Cancers (Basel)2022
34295468Multi-drug-resistance efflux in cisplatin-naive and cisplatin-exposed A2780 ovarian cancer cells responds differently to cell culture dimensionality.Mol Clin Oncol2021
34383182Dose predictions for [<sup>177</sup>Lu]Lu-DOTA-panitumumab F(ab')<sub>2</sub> in NRG mice with HNSCC patient-derived tumour xenografts based on [<sup>64</sup>Cu]Cu-DOTA-panitumumab F(ab')<sub>2</sub> - implications for a PET theranostic strategy.EJNMMI Radiopharm Chem2021
34813980Side population analysis in clear cell renal cell carcinoma.Biochem Biophys Res Commun2021
32347842A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness.Biomater Sci2020
31969334PI3K Inhibitors Curtail MYC-Dependent Mutant p53 Gain-of-Function in Head and Neck Squamous Cell Carcinoma.Clin Cancer Res2020
31864959Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer.Oral Oncol2020
31683122Gels for Live Analysis of Compartmentalized Environments (GLAnCE): A tissue model to probe tumour phenotypes at tumour-stroma interfaces.Biomaterials2020
33059733TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma.J Exp Clin Cancer Res2020
33111077Establishment and Use of Patient-Derived Xenograft Models for Drug Testing in Head and Neck Squamous Cell Carcinoma.STAR Protoc2020
32970704Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models.PLoS One2020
32968282Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.Nature2020
32245446Stem/progenitor cell marker expression in clear cell renal cell carcinoma: a potential relationship with the immune microenvironment to be explored.BMC Cancer2020
32434219Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21.J Exp Med2020
32514162Low junctional adhesion molecule-A expression is associated with an epithelial to mesenchymal transition and poorer outcomes in high-grade serous carcinoma of uterine adnexa.Mod Pathol2020
30468243A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth.Int J Cancer2019
31665182Correction: Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma.PLoS One2019
32694814Metabolic regulation of dermal fibroblasts contributes to skin extracellular matrix homeostasis and fibrosis.Nat Metab2019
31242384MicroSPECT/CT Imaging of Cell-Line and Patient-Derived EGFR-Positive Tumor Xenografts in Mice with Panitumumab Fab Modified with Hexahistidine Peptides To Enable Labeling with <sup>99m</sup>Tc(I) Tricarbonyl Complex.Mol Pharm2019
30981729N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer.Cell Syst2019
30829484Cytometry of Reaction Rate Constant: Measuring Reaction Rate Constant in Individual Cells To Facilitate Robust and Accurate Analysis of Cell-Population Heterogeneity.Anal Chem2019
30788424Patient-derived xenografts: a promising resource for preclinical cancer research.Mol Cell Oncol2019
29071678High Throughput Flow Cytometry for Cell Surface Profiling.Methods Mol Biol2018
29899842High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines.Oncotarget2018
30380421Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma.Cell Rep2018
29490260A TRACER 3D Co-Culture tumour model for head and neck cancer.Biomaterials2018
29715275Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma.PLoS One2018
29681158Proteomic Analysis of Cancer-Associated Fibroblasts Reveals a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma.J Proteome Res2018
27283126Preservation of the 3D Phenotype Upon Dispersal of Cultured Cell Spheroids Into Monolayer Cultures.J Cell Biochem2017
28273451Interrogation of Functional Cell-Surface Markers Identifies CD151 Dependency in High-Grade Serous Ovarian Cancer.Cell Rep2017
28475899An Immune Atlas of Clear Cell Renal Cell Carcinoma.Cell2017
28799592Rapid determination of the tumour stroma ratio in squamous cell carcinomas with desorption electrospray ionization mass spectrometry (DESI-MS): a proof-of-concept demonstration.Analyst2017
28862278Correction: Rapid determination of the tumour stroma ratio in squamous cell carcinomas with desorption electrospray ionization mass spectrometry (DESI-MS): a proof-of-concept demonstration.Analyst2017
28067913Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.Nat Genet2017
26054050Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells.J Cell Biochem2016
26397062Clonal evolution and tumor-initiating cells: New dimensions in cancer patient treatment.Crit Rev Clin Lab Sci2016
27631341Patterning cellular compartments within TRACER cultures using sacrificial gelatin printing.Biofabrication2016
27121191Cancer stem cells are underestimated by standard experimental methods in clear cell renal cell carcinoma.Sci Rep2016
27422173Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine.BMC Cancer2016
25826681Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.PLoS One2015
26517673Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma.Oncotarget2015
25170899Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity.PLoS One2014
25551685Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.Respir Res2014
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Collaborators

Jalna Meens
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 14
Anthony C Nichols
University of Western Ontario
Co-authored papers 8
Craig Gedye
Hunter Medical Research Institute, University of Newcastle
Co-authored papers 8
Geoffrey Liu
The Princess Margaret Cancer Centre/University of Toronto
Co-authored papers 8
Wei Xu
Princess Margaret Cancer Centre
Co-authored papers 6
Joe S Mymryk
University of Western Ontario
Co-authored papers 6
Paul C Boutros
University of California los angeles
Co-authored papers 6
John W Barrett
University of Western Ontario
Co-authored papers 6
Luigi Naldini
Vita-Salute San Raffaele University
Co-authored papers 6
Kara M Ruicci
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 5
Stephanie Danielle MacNeil
Schulich School of Medicine and Dentistry, Western University
Co-authored papers 5
Nicole Pinto
School of Public Policy at the University of Calgary
Co-authored papers 5
John Yoo
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 5
Kevin Fung
Schulich School of Medicine & Dentistry, Western University, Victoria Hospital
Co-authored papers 5
Henry Thai
Princess Margaret Cancer Centre
Co-authored papers 4
Joerg Schwock
University of Toronto
Co-authored papers 4
Antonio Finelli
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 4
Gail Darling
University of Toronto
Co-authored papers 4
Lorin Dodbiba
McMaster University
Co-authored papers 4
David P Goldstein
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 4
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 4
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 4
Zhuo Chen
The First Hospital of Lanzhou University
Co-authored papers 4
Sergey N Krylov
York University
Co-authored papers 4
Hala Girgis
Toronto General Hospital
Co-authored papers 4
Robert G Bristow
University of Toronto
Co-authored papers 4
Jennifer Teichman
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Andrew Fleet
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Release 1.2