Skip to Main Content

Author Details

Darren Hargrave
1992
157
43
PMIDPaper TitleJournal TitlePublished Year
37978284The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.Nat Med2024
37944912Pediatric low-grade glioma: State-of-the-art and ongoing challenges.Neuro Oncol2024
36843390DNA methylation-based classification of glioneuronal tumours synergises with histology and radiology to refine accurate molecular stratification.2023
36375115Efficacy and Safety of Trametinib Monotherapy or in Combination With Dabrafenib in Pediatric <i>BRAF</i> V600-Mutant Low-Grade Glioma.J Clin Oncol2023
36239316A nationwide evaluation of bevacizumab-based treatments in pediatric low-grade glioma in the UK: Safety, efficacy, visual morbidity, and outcomes.Neuro-Oncology2023
35562551Visual outcomes and predictors in optic pathway glioma: a single centre study.Eye2023
38022892A novel diagnostic method for a rare fungus: FcMBL facilitates identification in an immunocompromised neonate.2023
37733309Dabrafenib plus Trametinib in Pediatric Glioma with <i>BRAF</i> V600 Mutations.N Engl J Med2023
37643378Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory <i>BRAF</i> V600-Mutant Pediatric High-Grade Glioma.J Clin Oncol2023
37091147Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks.Front Oncol2023
36884302Dabrafenib, alone or in combination with trametinib, in BRAF V600-mutated pediatric Langerhans cell histiocytosis.2023
37075810LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.Neuro Oncol2023
36808285Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: Safety, efficacy, biomarker, and pharmacokinetics-CheckMate 908.Neuro Oncol2023
36790496Atypical teratoid rhabdoid tumours (ATRTs)-a 21-year institutional experience.2023
35159015A 40-Year Cohort Study of Evolving Hypothalamic Dysfunction in Infants and Young Children (<3 years) with Optic Pathway Gliomas.Cancers2022
35814457Neurological Symptom Improvement After Re-Irradiation in Patients With Diffuse Intrinsic Pontine Glioma: A Retrospective Analysis of the SIOP-E-HGG/DIPG Project.Front Oncol2022
35489353Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group.Lancet Oncol2022
36335782Paediatric Strategy Forum for medicinal product development in mitogen-activated protein kinase pathway inhibitors: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.Eur J Cancer2022
35799614Multimorbidity patterns and risk of hospitalisation in children: A population cohort study of 3.6 million children in England, with illustrative examples from childhood cancer survivors.Lancet Regional Health - Europe, The2022
35733513Pediatric high-grade gliomas and the WHO CNS Tumor Classification-Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates.Neurooncol Adv2022
35412366MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.Radiology2022
35788692MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus.Neuro Oncol2022
35536420Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [F]FDG: version 1.0.European Journal of Nuclear Medicine and Molecular Imaging2022
35976451Convection-Enhanced Delivery in Children: Techniques and Applications.Advances and technical standards in neurosurgery2022
34737188DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition.Cancer Discovery2022
35178860Location, symptoms, and management of plexiform neurofibromas in 127 children with neurofibromatosis 1, attending the National Complex Neurofibromatosis 1 service, 2018-2019.American Journal of Medical Genetics, Part A2022
34546642Comprehensive analysis of the ErbB receptor family in pediatric nervous system tumors and rhabdomyosarcoma.Pediatr Blood Cancer2022
34595479Transitioning to molecular diagnostics in pediatric high-grade glioma: experiences with the 2016 WHO classification of CNS tumors.Neurooncol Adv2021
33542327Classification of paediatric brain tumours by diffusion weighted imaging and machine learning.Scientific Reports2021
34169282Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients.Neurooncol Adv2021
34168987Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors.Front Oncol2021
33797808Identifying cellular signalling molecules in developmental disorders of the brain: Evidence from focal cortical dysplasia and tuberous sclerosis.Neuropathol Appl Neurobiol2021
33532921Neurosurgical experience of managing optic pathway gliomas.Child's Nervous System2021
33664107A Diagnostic Algorithm for Posterior Fossa Tumors in Children: A Validation Study.AJNR Am J Neuroradiol2021
33977272MRI-based radiomics for prognosis of pediatric diffuse intrinsic pontine glioma: an international study.Neurooncol Adv2021
32705327Spectrum of neuroimaging findings post-proton beam therapy in a large pediatric cohort.Child's Nervous System2021
33241451Surveillance imaging of grade 1 astrocytomas in children: can duration and frequency of follow-up imaging and the use of contrast agents be reduced?Neuroradiology2021
32628746NF1 optic pathway glioma: analyzing risk factors for visual outcome and indications to treat.Neuro-Oncology2021
33226200Parents' responses to prognostic disclosure at diagnosis of a child with a high-risk brain tumor: Analysis of clinician-parent interactions and implications for clinical practice.Pediatric Blood and Cancer2021
33325069A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC).Neuropathol Appl Neurobiol2021
34381018Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation.Cell Death and Disease2021
31504816Molecular correlates of cerebellar mutism syndrome in medulloblastoma.Neuro Oncol2020
31786093DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.Lancet Child Adolesc Health2020
32238360Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.Cancer Discov2020
31924736Radiological Evaluation of Newly Diagnosed Non-Brainstem Pediatric High-Grade Glioma in the HERBY Phase II Trial.Clin Cancer Res2020
32451331A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in <i>BRAF</i>-Driven Pediatric Low-Grade Glioma Cells.Mol Cancer Ther2020
33038669Quantitative MRI demonstrates abnormalities of the third ventricle subventricular zone in neurofibromatosis type-1 and sporadic paediatric optic pathway glioma.NeuroImage: Clinical2020
32537177Systematic review: measurement properties of patient-reported outcome measures evaluated with childhood brain tumor survivors or other acquired brain injury.Neuro-Oncology Practice2020
32859926Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity.Nat Commun2020
33014399Regarding "Neuro-Oncology Practice Clinical Debate: targeted therapy vs conventional chemotherapy in pediatric low-grade glioma".Neuro-Oncology Practice2020
  • 1 - 50 of 157

Recommended Authors

Collaborators

The Hospital for Sick Children
Co-authored papers 32
Co-authored papers 23
Co-authored papers 18
Co-authored papers 16
Co-authored papers 14
Co-authored papers 12
Co-authored papers 12
Brain Tumor Institute, Children's National Hospital
Co-authored papers 12
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 12
Fondazione IRCCS Istituto Nazionale dei Tumori
Co-authored papers 11
Co-authored papers 10
Co-authored papers 10
Boston Children's Hospital and Harvard Medical School
Co-authored papers 10
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 10
Co-authored papers 9
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 9
Co-authored papers 7
Institut de Psychiatrie et Neurosciences de Paris (IPNP), INSERM, University of Paris
Co-authored papers 7
The Hospital for Sick Children
Co-authored papers 6
St. Jude Children's Research Hospital
Co-authored papers 6
Co-authored papers 6
The Institute of Cancer Research
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
Institut Curie and University Paris Cite
Co-authored papers 6
Co-authored papers 6
UCL Great Ormond Street Institute of Child Health, University College London
Co-authored papers 5