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Author Details
Full Name
Todd C McDevitt
Affiliation
Gladstone Institute of Cardiovascular Disease
ORCID
Career Start Year
1999
Papers
116
H Index
42
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37354899
Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells.
Dev Cell
2023
37938000
Hepatitis C virus infects and perturbs liver stem cells.
mBio
2023
35232252
Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system.
Open Biol
2022
35618897
Self-Assembled Heterotypic Cardiac Spheroids from Human Pluripotent Stem Cells.
Methods Mol Biol
2022
36177947
Engineering multicellular living systems-a Keystone Symposia report.
Ann N Y Acad Sci
2022
36238834
Diseased, differentiated and difficult: Strategies for improved engineering of <i>in vitro</i> neurological systems.
Front Cell Neurosci
2022
33414560
Mouse gastruloids take heart.
Nat Rev Cardiol
2021
33828315
The NIH Somatic Cell Genome Editing program.
Nature
2021
33723017
SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
Sci Transl Med
2021
34861147
Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids.
Cell Stem Cell
2021
34403849
Bioengineered optogenetic model of human neuromuscular junction.
Biomaterials
2021
34485306
Allele-Specific Gene Editing Rescues Pathology in a Human Model of Charcot-Marie-Tooth Disease Type 2E.
Front Cell Dev Biol
2021
33979602
Deep neural net tracking of human pluripotent stem cells reveals intrinsic behaviors directing morphogenesis.
Stem Cell Reports
2021
34339055
Developmental lineage of human pluripotent stem cell-derived cardiac fibroblasts affects their functional phenotype.
FASEB J
2021
34142711
Axial elongation of caudalized human organoids mimics aspects of neural tube development.
Development
2021
33340357
Engineering the Spatiotemporal Mosaic Self-Patterning of Pluripotent Stem Cells.
Methods Mol Biol
2021
33472820
Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease.
J Neurosci
2021
33471965
Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids.
Biotechnol J
2021
32515433
Microfluidic perfusion modulates growth and motor neuron differentiation of stem cell aggregates.
Analyst
2020
31634681
Imaging the developing human external and internal urogenital organs with light sheet fluorescence microscopy.
Differentiation
2020
31922007
Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration.
Sci Adv
2020
31705126
Author Correction: V2a interneuron differentiation from mouse and human pluripotent stem cells.
Nat Protoc
2020
32935097
SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients.
bioRxiv
2020
32111148
Single-Cell Determination of Cardiac Microtissue Structure and Function Using Light Sheet Microscopy.
Tissue Eng Part C Methods
2020
30958455
Comparable Decellularization of Fetal and Adult Cardiac Tissue Explants as 3D-like Platforms for In Vitro Studies.
J Vis Exp
2019
31759947
Automated Design of Pluripotent Stem Cell Self-Organization.
Cell Syst
2019
31628445
V2a interneuron differentiation from mouse and human pluripotent stem cells.
Nat Protoc
2019
30968748
Phenotypic Variation Between Stromal Cells Differentially Impacts Engineered Cardiac Tissue Function.
Tissue Eng Part A
2019
29292168
Microparticle-mediated sequestration of cell-secreted proteins to modulate chondrocytic differentiation.
Acta Biomater
2018
31069321
Perspective: The promise of multi-cellular engineered living systems.
APL Bioeng
2018
31069307
A rapid method for determining protein diffusion through hydrogels for regenerative medicine applications.
APL Bioeng
2018
30291250
Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment.
Nat Commun
2018
30262218
Three-dimensional imaging of the developing human fetal urogenital-genital tract: Indifferent stage to male and female differentiation.
Differentiation
2018
30446658
Author Correction: Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment.
Nat Commun
2018
30298816
Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference.
Elife
2018
29389399
Lightsheet fluorescence microscopy of branching human fetal kidney.
Kidney Int
2018
29518080
Biophysical subsets of embryonic stem cells display distinct phenotypic and morphological signatures.
PLoS One
2018
26921003
Expansion and angiogenic potential of mesenchymal stem cells from patients with critical limb ischemia.
J Vasc Surg
2017
28438991
Differentiation of V2a interneurons from human pluripotent stem cells.
Proc Natl Acad Sci U S A
2017
28170190
Enhanced Immunosuppression of T Cells by Sustained Presentation of Bioactive Interferon-γ Within Three-Dimensional Mesenchymal Stem Cell Constructs.
Stem Cells Transl Med
2017
28338419
Competitive Protein Binding Influences Heparin-Based Modulation of Spatial Growth Factor Delivery for Bone Regeneration.
Tissue Eng Part A
2017
28965974
Tridimensional configurations of human mesenchymal stem/stromal cells to enhance cell paracrine potential towards wound healing processes.
J Biotechnol
2017
29079806
Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells.
Sci Rep
2017
28952622
A microfluidic trap array for longitudinal monitoring and multi-modal phenotypic analysis of individual stem cell aggregates.
Lab Chip
2017
28645809
Enhanced in vivo retention of low dose BMP-2 via heparin microparticle delivery does not accelerate bone healing in a critically sized femoral defect.
Acta Biomater
2017
28577903
The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids.
J Biomech
2017
27330934
Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells.
Curr Stem Cell Rep
2016
32263389
Environmental manipulation to promote stem cell survival in vivo: use of aggregation, oxygen carrier, and BMP-2 co-delivery strategies.
J Mater Chem B
2016
26658353
Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny.
Methods
2016
26597546
Mineral particles modulate osteo-chondrogenic differentiation of embryonic stem cell aggregates.
Acta Biomater
2016
1 - 50 of 116
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