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Author Details

Howard Levy
Howard Levy Consulting LLC
1966
109
38
PMIDPaper TitleJournal TitlePublished Year
33960073Efficacy and safety of subcutaneous prophylaxis with dalcinonacog alfa in adults with haemophilia B.Haemophilia2021
33790846Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation.Front Neurol2021
33540485Safety, pharmacokinetics, and pharmacodynamics of a next-generation subcutaneously administered coagulation factor IX variant, dalcinonacog alfa, in previously treated hemophilia B patients.J Thromb Haemost2021
34430790Subcutaneous engineered factor VIIa marzeptacog alfa (activated) in hemophilia with inhibitors: Phase 2 trial of pharmacokinetics, pharmacodynamics, efficacy, and safety.Res Pract Thromb Haemost2021
33112889Preclinical evaluation of a next-generation, subcutaneously administered, coagulation factor IX variant, dalcinonacog alfa.PLoS One2020
30450637Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke.Ann Neurol2019
30308028Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.PLoS One2018
28378932The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso-occlusive crises.Am J Hematol2017
27515331Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction.J Am Coll Cardiol2016
27803392Selecting Patients for Intra-Arterial Therapy in the Context of a Clinical Trial for Neuroprotection.Stroke2016
25609336Comparison of chromogenic and ELISA functional C1 inhibitor tests in diagnosing hereditary angioedema.J Allergy Clin Immunol Pract2015
25803135Prevalence of hereditary angioedema in untested first-degree blood relatives of known subjects with hereditary angioedema.Allergy Asthma Proc2015
23979365A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation.Crit Care Med2013
24372304Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult volunteers.Curr Pharm Des2013
21455059Evaluation of MP4OX for prevention of perioperative hypotension in patients undergoing primary hip arthroplasty with spinal anesthesia: a randomized, double-blind, multicenter study.Anesthesiology2011
21317165A double-blind, randomized, multicenter study of MP4OX for treatment of perioperative hypotension in patients undergoing primary hip arthroplasty under spinal anesthesia.Anesth Analg2011
21341394CURB-65, PSI, and APACHE II to assess mortality risk in patients with severe sepsis and community acquired pneumonia in PROWESS.J Intensive Care Med2011
17350452Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.Lancet2007
17895486Simplified pharmacoeconomics of critical care and severe sepsis.J Intensive Care Med2007
17637378Gouty panniculitis in a healthy male.J Am Acad Dermatol2007
17699383Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis.Clin J Am Soc Nephrol2007
17253918Error rates among clinical pharmacists in calculating the APACHE II score.Pharmacotherapy2007
16575354ENHANCE: results of a global open-label trial of drotrecogin alfa (activated) in children with severe sepsis.Pediatr Crit Care Med2006
15632220Obesity does not alter the pharmacokinetics of drotrecogin alfa (activated) in severe sepsis.Ann Pharmacother2005
16192478Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death.N Engl J Med2005
16277714Application of a population-based severity scoring system to individual patients results in frequent misclassification.Crit Care2005
16277711Steroid use in PROWESS severe sepsis patients treated with drotrecogin alfa (activated).Crit Care2005
15891319Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study.Crit Care Med2005
14990780Comment: obese man treated with drotrecogin alfa (activated).Ann Pharmacother2004
15640632Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial.Crit Care Med2004
15189943Extended evaluation of recombinant human activated protein C United States Trial (ENHANCE US): a single-arm, phase 3B, multicenter study of drotrecogin alfa (activated) in severe sepsis.Chest2004
15494907Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America.Clin Infect Dis2004
14769742Transpyloric feeding tube placement in critically ill patients using electromyogram and erythromycin infusion.Chest2004
12544987Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis.Crit Care Med2003
12939918The value of innovation.S Afr Med J2003
14501959The clinical evaluation committee in a large multicenter phase 3 trial of drotrecogin alfa (activated) in patients with severe sepsis (PROWESS): role, methodology, and results.Crit Care Med2003
12582406Rickettsialpox in a patient with HIV infection.J Am Acad Dermatol2003
12830408Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated).Clin Infect Dis2003
12794395Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial.Crit Care Med2003
12523456Erythromycin accelerates gastric emptying in a dose-response manner in healthy subjects.Pharmacotherapy2003
11927905Treatment of severe tricyclic antidepressant overdose with extracorporeal sorbent detoxification.Adv Ren Replace Ther2002
11398691Equal aspiration rates in gastrically and transpylorically fed critically ill patients.Intensive Care Med2001
11310516Confirming the reliability of the sedation-agitation scale administered by ICU nurses without experience in its use.Pharmacotherapy2001
11800089Treatment of systemic inflammatory response syndrome by push-pull powdered sorbent pheresis: a Phase 1 clinical trial.Ther Apher2001
11588451Gastric feeding with erythromycin is equivalent to transpyloric feeding in the critically ill.Crit Care Med2001
11703524Disseminated histoplasmosis presenting as pyoderma gangrenosum-like lesions in a patient with acquired immunodeficiency syndrome.Int J Dermatol2001
11502657Hantavirus pulmonary syndrome due to Andes virus in Temuco, Chile: clinical experience with 16 adults.Chest2001
10910024Push-pull sorbent-based pheresis and hemodiabsorption in the treatment of hepatic failure: preliminary results of a clinical trial with the BioLogic-DTPF System.Ther Apher2000
11310904Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients.Intensive Care Med2000
11011786A multicenter, prospective study of the placement of transpyloric feeding tubes with assistance of a magnetic device. The Magnet-Guided Enteral Feeding Tube Study Group.JPEN J Parenter Enteral Nutr2000
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Collaborators

Centre Hospitalier Regional Mons-Hainaut
Co-authored papers 7
Universite Paris Descartes
Co-authored papers 6
University of Kansas Medical Center
Co-authored papers 5
Vanderbilt University
Co-authored papers 5
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Clinical and Translational Science Institute, University of Florida
Co-authored papers 3
Infectious Disease Division at Brown University Warren Alpert Medical School
Co-authored papers 3
Erasme Hospital, Universite Libre de Bruxelles
Co-authored papers 3
Clinical Epidemiology
Co-authored papers 2
University of Pittsburgh Medical Center
Co-authored papers 2
Vanderbilt University Medical Center
Co-authored papers 2
University of Florida
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
University of Massachusetts Medical School - Baystate
Co-authored papers 2
Co-authored papers 2
Allergy and Asthma Research Associates Research Center
Co-authored papers 2
Co-authored papers 2
Barrow Neurological Institute, St Joseph's Hospital and Medical Center
Co-authored papers 2
University of Utah
Co-authored papers 1
Veterans Affairs Medical Center San Diego
Co-authored papers 1
Columbia University
Co-authored papers 1
University of Texas Health
Co-authored papers 1
Duke Clinical Research Institute, Duke University
Co-authored papers 1
University of Cincinnati Medical Center
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Ghent University Hospital, and Research Foundation Flanders (FWO), Ghent University
Co-authored papers 1
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 1
Vanderbilt University
Co-authored papers 1
Canterbury District Health Board
Co-authored papers 1