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Author Details

Gideon Schreiber
1988
147
64
PMIDPaper TitleJournal TitlePublished Year
37503026RBD-based high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways.2023
37796123Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.J Virol2023
37193706Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants.2023
37114129Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib and .2023
36736338Enhanced transmissibility, infectivity, and immune resistance of the SARS-CoV-2 omicron XBB.1.5 variant.2023
37506197Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.Sci Immunol2023
35081335SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.Cell2022
35711666Perspectives: SARS-CoV-2 Spike Convergent Evolution as a Guide to Explore Adaptive Advantage.Frontiers in Cellular and Infection Microbiology2022
36157590Diffusion of small molecule drugs is affected by surface interactions and crowder proteins.iScience2022
35568035Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike.Cell2022
36198317Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.Cell2022
35608934Gelatin Stabilizes Nebulized Proteins in Pulmonary Drug Delivery against COVID-19.ACS Biomaterials Science and Engineering2022
36320402Protein quaternary structures in solution are a mixture of multiple forms.Chem Sci2022
35921522Genetically Engineered MRI-Trackable Extracellular Vesicles as SARS-CoV-2 Mimetics for Mapping ACE2 Binding .ACS Nano2022
35597550In vitro Evolution of Uracil Glycosylase Towards DnaKJ and GroEL Binding Evolves Different Misfolded States.Journal of Molecular Biology2022
36507224The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant.iScience2022
34968415The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance.Cell Rep2022
34826176De novo developed protein binders mimicking Interferon lambda signaling.FEBS J2022
34809429A Protein-Engineered, Enhanced Yeast Display Platform for Rapid Evolution of Challenging Targets.ACS Synthetic Biology2021
34171266SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity.Cell Host Microbe2021
34196543Protein Engineering in the Design of Protein-Protein Interactions: SARS-CoV-2 Inhibitors as a Test Case.Biochemistry2021
33647289Line-FRAP, A Versatile Method to Measure Diffusion Rates In Vitro and In Vivo.Journal of Molecular Biology2021
34400835SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution.Nat Microbiol2021
34981049Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.bioRxiv2021
34437657SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon.PLoS Pathogens2021
34890433Correction: SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon.PLoS Pathogens2021
34813358IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon-induced JAK-STAT signaling and activating STATs.Science Signaling2021
33117408The Role of Type I Interferons in the Pathogenesis and Treatment of COVID-19.Frontiers in Immunology2020
31341069Reply to Hasenkrug et al., "Different Biological Activities of Specific Interferon Alpha Subtypes".mSphere2019
31606122Competing Ligands Can Both Obstruct and Enhance Protein-Complex Formation.Biophysical Journal2019
30760614Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects.mSphere2019
31207241CRISPR/Cas9-based Knockout Strategy Elucidates Components Essential for Type 1 Interferon Signaling in Human HeLa Cells.Journal of Molecular Biology2019
29324226Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo.Cell Host Microbe2018
30142226Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication.PLoS Pathog2018
29671590Selecting for Fast Protein-Protein Association As Demonstrated on a Random TEM1 Yeast Library Binding BLIP.Biochemistry2018
28289098The molecular basis for differential type I interferon signaling.Journal of Biological Chemistry2017
28648616Dynamic Modulation of Binding Affinity as a Mechanism for Regulating Interferon Signaling.J Mol Biol2017
28784664Quantifying enzyme activity in living cells.Journal of Biological Chemistry2017
29211984Promiscuous Protein Binding as a Function of Protein Stability.Structure2017
27744288Direct determination of enzyme kinetic parameters from single reactions using a new progress curve analysis tool.Protein Engineering, Design and Selection2017
27917878Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex.Nat Commun2016
26679999Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain.Journal of Biological Chemistry2016
27956635Low-stringency selection of TEM1 for BLIP shows interface plasticity and selection for faster binders.Proceedings of the National Academy of Sciences of the United States of America2016
26158644Fine Tuning of a Type 1 Interferon Antagonist.PLoS ONE2015
25687684The molecular basis for functional plasticity in type I interferon signaling.Trends in Immunology2015
25721402A robust type I interferon gene signature from blood RNA defines quantitative but not qualitative differences between three major IFNβ drugs in the treatment of multiple sclerosis.Hum Mol Genet2015
25193661Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosis.Journal of Biological Chemistry2014
24416207Bridging the species divide: transgenic mice humanized for type-I interferon response.PLoS ONE2014
25043006Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression.Nature2014
24866020Multifaceted activities of type I interferon are revealed by a receptor antagonist.Sci Signal2014
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Medical Research Council Laboratory of Molecular Biology
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The A. Silberman Institute of Life Sciences, The Hebrew University of Jerusalem
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Graduate School of Medicine, Kyoto University
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Weizmann Institute of Science
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The Institute of Medical Science, The University of Tokyo
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University of Illinois Chicago
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University of Oxford
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Center for Molecular Biology (ZMBH), Heidelberg University
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Icahn School of Medicine at Mount Sinai
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Roslin Institute, University of Edinburgh
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Laboratorio de Virologia do Instituto Leonidas e Maria Deane
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University of Illinois at Chicago
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Weizmann Institute of Science
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Vaccine and Gene Therapy Institute, Oregon Health & Science University
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Harwell Science & Innovation Campus
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Frederick National Laboratory
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Weizmann Institute of Science
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VIB-VUB Center for Structural Biology
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University of Leeds
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