Author details

Full Name

Lihua Julie Zhu

Affiliation

ORCID

Career Start Year

2007

Papers

139

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36658165	Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1.		2023
37951219	HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B.		2023
37756546	Runx1-R188Q germ line mutation induces inflammation and predisposition to hematologic malignancies in mice.	Blood Adv	2023
37910503	The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin Î±6 mRNA splicing.		2023
37905100	Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells.		2023
37880368	Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells.		2023
37790484	Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer.		2023
37156841	Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.		2023
37142692	EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance.		2023
37134151	Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer.	Sci Transl Med	2023
37292647	Gene editing without <i>ex vivo</i> culture evades genotoxicity in human hematopoietic stem cells.	bioRxiv	2023
34376056	Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities.	Human Gene Therapy	2022
36369293	Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.	Nat Commun	2022
36238687	scATACpipe: A nextflow pipeline for comprehensive and reproducible analyses of single cell ATAC-seq data.	Frontiers in Cell and Developmental Biology	2022
36170811	De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.	Cell Reports	2022
36037231	Repression of essential cell cycle genes increases cellular fitness.	PLoS Genet	2022
36070530	Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors.	CRISPR Journal	2022
36496438	A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis.		2022
35064134	Genome-wide detection of CRISPR editing in vivo using GUIDE-tag.	Nat Commun	2022
35165413	LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.	Nat Cell Biol	2022
34620709	Hinfp is a guardian of the somatic genome by repressing transposable elements.	Proc Natl Acad Sci U S A	2021
34127199	Genome-wide detection and analysis of CRISPR-Cas off-targets.	Progress in Molecular Biology and Translational Science	2021
33473112	UPR<sup>mt</sup> scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans.	Nat Commun	2021
33526671	Consequences of aneuploidy in human fibroblasts with trisomy 21.	Proceedings of the National Academy of Sciences of the United States of America	2021
33620316	Deficient spermiogenesis in mice lacking <i>Rlim</i>.	Elife	2021
33507291	Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.	Blood	2021
34353903	The chromatin-binding domain of Ki-67 together with p53 protects human chromosomes from mitotic damage.	Proceedings of the National Academy of Sciences of the United States of America	2021
33184108	Replication Gaps Underlie BRCA Deficiency and Therapy Response.	Cancer Research	2021
34921133	EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis.	Nature Communications	2021
32831172	An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes.	eLife	2020
32430335	KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity.	Proceedings of the National Academy of Sciences of the United States of America	2020
32259481	Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.	Cell Stem Cell	2020
31740768	Adenine base editing in an adult mouse model of tyrosinaemia.	Nature Biomedical Engineering	2020
31586558	Alveolar progenitor cells in the mammary gland are dependent on the Î²4 integrin.	Developmental Biology	2020
32065070	Genomic Characterization of Endothelial Enhancers Reveals a Multifunctional Role for NR2F2 in Regulation of Arteriovenous Gene Expression.	Circulation Research	2020
32343701	The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network.	PLoS Genetics	2020
32219510	Distinct features of nucleolus-associated domains in mouse embryonic stem cells.	Chromosoma	2020
33156866	dagLogo: An R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data.	PLoS ONE	2020
32694795	Selenium detoxification is required for cancer-cell survival.	Nat Metab	2020
33027655	The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.	Cell Rep	2020
33023248	OneStopRNAseq: A Web Application for Comprehensive and Efficient Analyses of RNA-Seq Data.	Genes	2020
31199900	foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish.	Developmental Biology	2019
31801083	YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.	Cell Rep	2019
31735663	Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export.	Developmental Cell	2019
31235595	The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression.	Proc Natl Acad Sci U S A	2019
31133757	trackViewer: a Bioconductor package for interactive and integrative visualization of multi-omics data.	Nature Methods	2019
31276432	Conserved microRNA mediates heating tolerance in germ cells versus surrounding somatic cells.	RNA Biology	2019
31068472	Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.	Proceedings of the National Academy of Sciences of the United States of America	2019
30850535	Mitochondrial UPR repression during <i>Pseudomonas aeruginosa</i> infection requires the bZIP protein ZIP-3.	Proc Natl Acad Sci U S A	2019
30892626	Enhanced Cas12a editing in mammalian cells and zebrafish.	Nucleic Acids Research	2019