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Author Details

Abraham L Brass
University of Massachusetts Medical School
1995
53
36
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32367370Discovery of Zika Virus Dependency and Restriction Factors Using Flow-Based Arrayed CRISPR Screening for Identification of Targets (FACS-IT).Methods Mol Biol2020
32367370Discovery of Zika Virus Dependency and Restriction Factors Using Flow-Based Arrayed CRISPR Screening for Identification of Targets (FACS-IT).Methods Mol Biol2020
32391394Sulforaphane alters the acidification of the yeast vacuole.Microb Cell2020
32391394Sulforaphane alters the acidification of the yeast vacuole.Microb Cell2020
30355696Functional Mapping of Regions Involved in the Negative Imprinting of Virion Particle Infectivity and in Target Cell Protection by Interferon-Induced Transmembrane Protein 3 against HIV-1.J Virol2019
30355696Functional Mapping of Regions Involved in the Negative Imprinting of Virion Particle Infectivity and in Target Cell Protection by Interferon-Induced Transmembrane Protein 3 against HIV-1.J Virol2019
30640957Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes.PLoS Pathog2019
31501601A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model.Nat Med2019
31471524Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression.J Immunol2019
31448372Capsid-CPSF6 interaction: Master regulator of nuclear HIV-1 positioning and integration.J Life Sci (Westlake Village)2019
30894498OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism.Proc Natl Acad Sci U S A2019
30723129A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection.mBio2019
30716700Viral Infection or IFN-α Alters Mitotic Spindle Orientation by Modulating Pericentrin Levels.iScience2019
31501601A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model.Nat Med2019
31471524Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression.J Immunol2019
31448372Capsid-CPSF6 interaction: Master regulator of nuclear HIV-1 positioning and integration.J Life Sci (Westlake Village)2019
30894498OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism.Proc Natl Acad Sci U S A2019
30723129A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection.mBio2019
30716700Viral Infection or IFN-α Alters Mitotic Spindle Orientation by Modulating Pericentrin Levels.iScience2019
30640957Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes.PLoS Pathog2019
29677181Exploiting glycan topography for computational design of Env glycoprotein antigenicity.PLoS Comput Biol2018
30173955Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration.Cell Host Microbe2018
29684735CRISPR genetic screens to discover host-virus interactions.Curr Opin Virol2018
29677181Exploiting glycan topography for computational design of Env glycoprotein antigenicity.PLoS Comput Biol2018
30173955Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration.Cell Host Microbe2018
29684735CRISPR genetic screens to discover host-virus interactions.Curr Opin Virol2018
26997589Functional Genomic Strategies for Elucidating Human-Virus Interactions: Will CRISPR Knockout RNAi and Haploid Cells?Adv Virus Res2016
27342126Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.Cell Rep2016
26997589Functional Genomic Strategies for Elucidating Human-Virus Interactions: Will CRISPR Knockout RNAi and Haploid Cells?Adv Virus Res2016
27268505The IFITMs Inhibit Zika Virus Replication.Cell Rep2016
27680706Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.Nature2016
27680706Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.Nature2016
27268505The IFITMs Inhibit Zika Virus Replication.Cell Rep2016
27342126Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.Cell Rep2016
26212330RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus.Cell Rep2015
26651948Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Cell Host Microbe2015
26212330RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus.Cell Rep2015
26586435Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration.Cell Rep2015
26651948Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.Cell Host Microbe2015
26586435Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration.Cell Rep2015
24458634Immunology. The fiery side of HIV-induced T cell death.Science2014
25373910Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.Cell Rep2014
25526311Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.Immunity2014
24458634Immunology. The fiery side of HIV-induced T cell death.Science2014
24335308A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication.J Virol2014
24699674IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion.PLoS Pathog2014
25526311Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.Immunity2014
25373910Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.Cell Rep2014
24699674IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion.PLoS Pathog2014
24335308A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication.J Virol2014
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Collaborators

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
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Broad Institute of MIT and Harvard
Co-authored papers 5
Ragon Institute of Mass General
Co-authored papers 5
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Wellcome Sanger Institute
Co-authored papers 2
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
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Frederick National Laboratory for Cancer Research, National Cancer Institute
Co-authored papers 1
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Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Institute of Medical Virology, University of Zurich
Co-authored papers 1
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 1
Massachusetts Institute of Technology
Co-authored papers 1
Wellcome Sanger Institute
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Roche Pharma Research and Early Development
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
College of Veterinary Medicine, Oregon State University
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Carlson College of Veterinary Medicine, Oregon State University
Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
Louisiana State University
Co-authored papers 1
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Mater Research Institute-UQ, Translational Research Institute
Co-authored papers 1
University of Utah School of Medicine
Co-authored papers 1
Max Planck Institute for Infection Biology
Co-authored papers 1