Author details

Full Name

Xiaokun Shu

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37349581	Polarized focal adhesion kinase activity within a focal adhesion during cell migration.		2023
37896782	Spying on SARS-CoV-2 with Fluorescent Tags and Protease Reporters.		2023
36857446	ATM-SPARK: A GFP phase separation-based activity reporter of ATM.		2023
36604514	Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2.	Nat Microbiol	2023
37521779	Chemogenetic Minitool for Dissecting the Roles of Protein Phase Separation.		2023
37419111	Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.	Mol Cell	2023
35041199	Riboflavin-binding proteins for singlet oxygen production.	Photochem Photobiol Sci	2022
34478458	Ethacridine inhibits SARS-CoV-2 by inactivating viral particles.	PLoS Pathog	2021
32848159	Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry.	Nat Commun	2020
31678813	Imaging dynamic cell signaling inÂ vivo with new classes of fluorescent reporters.	Current Opinion in Chemical Biology	2020
33140048	Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models.	bioRxiv	2020
30787421	Tailing miniSOG: structural bases of the complex photophysics of a flavin-binding singlet oxygen photosensitizing protein.	Sci Rep	2019
30821975	Designing a Green Fluorogenic Protease Reporter by Flipping a Beta Strand of GFP for Imaging Apoptosis in Animals.	J Am Chem Soc	2019
29411438	A rapid fluorogenic GPCR-Î²-arrestin interaction assay.	Protein Science	2018
30061717	Designed peptides that assemble into cross-Î± amyloid-like structures.	Nat Chem Biol	2018
30431263	Dynamic Imaging of Small Molecule Induced Protein-Protein Interactions in Living Cells with a Fluorophore Phase Transition Based Approach.	Analytical Chemistry	2018
29351851	Visualizing Dynamics of Cell Signaling InÂ Vivo with a Phase Separation-Based Kinase Reporter.	Molecular Cell	2018
29307513	Visualizing Dynamics of Cell Signaling InÂ Vivo with a Phase Separation-Based Kinase Reporter.	Molecular Cell	2018
27814948	The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins.	Trends Biochem Sci	2017
28915023	Detecting Activity at Different Length Scales: From Subdiffraction to Whole-Animal Activity.	Biochemistry	2017
28065655	Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System.	Cell Chemical Biology	2017
26690964	Structure-guided design of a reversible fluorogenic reporter of protein-protein interactions.	Protein Science	2016
27220724	Photoactivatable protein labeling by singlet oxygen mediated reactions.	Bioorg Med Chem Lett	2016
27479328	A far-red fluorescent protein evolved from a cyanobacterial phycobiliprotein.	Nat Methods	2016
27471775	Structural Determinants of Improved Fluorescence in a Family of Bacteriophytochrome-Based Infrared Fluorescent Proteins: Insights from Continuum Electrostatic Calculations and Molecular Dynamics Simulations.	Biochemistry	2016
27447051	Rational Design of a GFP-Based Fluorogenic Caspase Reporter for Imaging Apoptosis InÂ Vivo.	Cell Chemical Biology	2016
26549191	Rational design of a monomeric and photostable far-red fluorescent protein for fluorescence imaging in vivo.	Protein Sci	2016
26098020	A naturally monomeric infrared fluorescent protein for protein labeling in vivo.	Nat Methods	2015
25733847	Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo.	Proceedings of the National Academy of Sciences of the United States of America	2015
24832154	An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging.	Nat Commun	2014
24905026	Singlet oxygen triplet energy transfer-based imaging technology for mapping protein-protein proximity in intact cells.	Nature Communications	2014
24210660	Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway.	Dev Cell	2013
23103964	Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy.	Nat Neurosci	2012
22532663	Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG.	Proc Natl Acad Sci U S A	2012
22857927	Picking faces out of a crowd: genetic labels for identification of proteins in correlated light and electron microscopy imaging.	Methods Cell Biol	2012
23063122	A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors.	Cell	2012
21413170	Spiers Memorial Lecture. Breeding and building molecular spies.	Faraday Discuss	2011
21483721	A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organisms.	PLoS Biol	2011
19423828	Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome.	Science	2009
19165727	Unique interactions between the chromophore and glutamate 16 lead to far-red emission in a red fluorescent protein.	Protein Science	2009
17918959	Ultrafast excited-state dynamics in the green fluorescent protein variant S65T/H148D. 1. Mutagenesis and structural studies.	Biochemistry	2007
17965188	An alternative excited-state proton transfer pathway in green fluorescent protein variant S205V.	Protein Science	2007
17918961	Ultrafast excited-state dynamics in the green fluorescent protein variant S65T/H148D. 3. Short- and long-time dynamics of the excited-state proton transfer.	Biochemistry	2007
17918960	Ultrafast excited-state dynamics in the green fluorescent protein variant S65T/H148D. 2. Unusual photophysical properties.	Biochemistry	2007
16893165	Novel chromophores and buried charges control color in mFruits.	Biochemistry	2006
15823036	Kindling fluorescent protein from Anemonia sulcata: dark-state structure at 1.38 A resolution.	Biochemistry	2005