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Author Details

Rupa Sridharan
Wisconsin Institute for Discovery, University of Wisconsin-Madison
2003
37
20
Leah V Schaffer (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37244909Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets.Nat Commun2023
37995701DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity.Stem Cell Reports2023
37507410LRRC10 regulates mammalian cardiomyocyte cell cycle during heart regeneration.NPJ Regen Med2023
37976354DOT1L is a barrier to histone acetylation during reprogramming to pluripotency.Sci Adv2023
34995500DOT1L inhibition enhances pluripotency beyond acquisition of epithelial identity and without immediate suppression of the somatic transcriptome.Stem Cell Reports2022
35733849Connecting the DOTs on Cell Identity.Front Cell Dev Biol2022
35705328Dynamic regulatory module networks for inference of cell type-specific transcriptional networks.Genome Res2022
36418052Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells.Genes Dev2022
32220307Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.Cell Metab2020
33237287HP1γ regulates H3K36 methylation and pluripotency in embryonic stem cells.Nucleic Acids Res2020
32208170Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence.Mol Cell2020
31067459Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency.Cell Rep2019
30181211The role of α-ketoglutarate-dependent proteins in pluripotency acquisition and maintenance.J Biol Chem2019
31583744Coordinated removal of repressive epigenetic modifications during induced reversal of cell identity.EMBO J2019
29298421Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells.Cell Rep2018
29358085Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance.Stem Cell Reports2018
28704058Elucidating Protein-DNA Interactions in Human Alphoid Chromatin via Hybridization Capture and Mass Spectrometry.J Proteome Res2017
28424352Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes.Genome Res2017
26905202Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage.Stem Cell Reports2016
26546512A predictive modeling approach for cell line-specific long-range regulatory interactions.Nucleic Acids Res2016
25650115Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways.Nat Commun2015
26338778A predictive modeling approach for cell line-specific long-range regulatory interactions.Nucleic Acids Res2015
23561438The nexus of Tet1 and the pluripotency network.Cell Stem Cell2013
23949383Initial characterization of histone H3 serine 10 O-acetylation.Epigenetics2013
23748610Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency.Nat Cell Biol2013
21624799Small RNAs loom large during reprogramming.Cell Stem Cell2011
21979373Mediator coordinates PIC assembly with recruitment of CHD1.Genes Dev2011
19250903Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.Mol Cell2009
19587682Chd1 regulates open chromatin and pluripotency of embryonic stem cells.Nature2009
19167336Role of the murine reprogramming factors in the induction of pluripotency.Cell2009
18397745Illuminating the black box of reprogramming.Cell Stem Cell2008
18287077Generation of human induced pluripotent stem cells from dermal fibroblasts.Proc Natl Acad Sci U S A2008
17681952Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.J Biol Chem2007
18371336Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.Cell Stem Cell2007
16452502Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response.Genes Dev2006
15737574Assembly of silent chromatin during thymocyte development.Semin Immunol2005
12871645Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor.Immunity2003
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Collaborators

Nur Zafirah Zaidan
Wisconsin Institute for Discovery, University of Wisconsin-Madison
Co-authored papers 6
Benjamin A Garcia
University of Pennsylvania
Co-authored papers 3
Ron Stewart
Co-authored papers 3
Amander T Clark
Center for Reproductive Science, University of California los angeles
Co-authored papers 2
Michael R Shortreed
University of Wisconsin-Madison
Co-authored papers 2
Wei Xie
Co-authored papers 2
Michael D Wilson
SickKids Research Institute
Co-authored papers 2
Mark Scalf
University of Wisconsin-Madison College of Letters and Sciences
Co-authored papers 2
Lloyd M Smith
University of Wisconsin-Madison College of Letters and Sciences
Co-authored papers 2
Gopal Iyer
University of Wisconsin School of Medicine and Public Health, University of Wisconsin
Co-authored papers 2
Michael Grunstein
University of California los angeles
Co-authored papers 1
Nicolas L Young
Baylor College of Medicine, USA Center for Precision Environmental Health
Co-authored papers 1
Stefan Schreiber
Co-authored papers 1
Katherine E Buxton
University of Wisconsin , 1101 University Avenue
Co-authored papers 1
Nathan Hotaling
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
Miguel Ramalho-Santos
University of Toronto
Co-authored papers 1
Michael Olivier
Co-authored papers 1
Konrad Hochedlinger
Co-authored papers 1
Christina Kendziorski
University of Wisconsin-Madison
Co-authored papers 1
Ajay A Vashisht
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Youngsoo Lee
University of Wisconsin-Madison School of Medicine and Public Health
Co-authored papers 1
Christopher J Westlake
Center for Cancer Research
Co-authored papers 1
Matteo Pellegrini
Co-authored papers 1
Jaime E Brown
Wisconsin Institute for Discovery, University of Wisconsin-Madison
Co-authored papers 1
Leah V Schaffer (CM4AI)
University of California San Diego
Co-authored papers 1
May Christine V Malicdan
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 1
Kolin J Walker
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Steve Horvath
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