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Author Details

Gary An
University of Vermont
1999
113
31
PMIDPaper TitleJournal TitlePublished Year
37562230Artificial Intelligence Optical Biopsy for Evaluating the Functional State of Wounds.J Surg Res2023
34826690Optical Biopsy Using a Neural Network to Predict Gene Expression From Photos of Wounds.J Surg Res2022
36479109Preparing for the next pandemic: Simulation-based deep reinforcement learning to discover and test multimodal control of systemic inflammation using repurposed immunomodulatory agents.Front Immunol2022
36039923Transcriptomic, Proteomic, and Morphologic Characterization of Healing in Volumetric Muscle Loss.Tissue Eng Part A2022
35935475Drug Development Digital Twins for Drug Discovery, Testing and Repurposing: A Schema for Requirements and Development.Front Syst Biol2022
35864898Editorial: Integration of Machine Learning and Computer Simulation in Solving Complex Physiological and Medical Questions.Front Physiol2022
35194613Preparing for the next COVID: Deep Reinforcement Learning trained Artificial Intelligence discovery of multi-modal immunomodulatory control of systemic inflammation in the absence of effective anti-microbials.bioRxiv2022
34048021Agent-Based Modeling of Systemic Inflammation: A Pathway Toward Controlling Sepsis.Methods Mol Biol2021
34721057The Use of Artificial Neural Networks to Forecast the Behavior of Agent-Based Models of Pathophysiology: An Example Utilizing an Agent-Based Model of Sepsis.Front Physiol2021
34744189Nested active learning for efficient model contextualization and parameterization: pathway to generating simulated populations using multi-scale computational models.Simulation2021
34452484Comparative Computational Modeling of the Bat and Human Immune Response to Viral Infection with the Comparative Biology Immune Agent Based Model.Viruses2021
34093225Utilizing the Heterogeneity of Clinical Data for Model Refinement and Rule Discovery Through the Application of Genetic Algorithms to Calibrate a High-Dimensional Agent-Based Model of Systemic Inflammation.Front Physiol2021
31706544A System Dynamics Model of Violent Trauma and the Role of Violence Intervention Programs.J Surg Res2020
30681362Deep Reinforcement Learning and Simulation as a Path Toward Precision Medicine.J Comput Biol2019
31497314Learning-accelerated discovery of immune-tumour interactions.Mol Syst Des Eng2019
31260168Agent-based models of inflammation in translational systems biology: A decade later.Wiley Interdiscip Rev Syst Biol Med2019
30993522Application of an external fixator vascular compressor (EFVC) in the critically injured trauma patient: a novel damage control technique.Eur J Orthop Surg Traumatol2019
29447154Examining the controllability of sepsis using genetic algorithms on an agent-based model of systemic inflammation.PLoS Comput Biol2018
30194523The Crisis of Reproducibility, the Denominator Problem and the Scientific Role of Multi-scale Modeling.Bull Math Biol2018
30886940Inflammation and Disease: Modelling and Modulation of the Inflammatory Response to Alleviate Critical Illness.Curr Opin Syst Biol2018
30577742High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow.BMC Bioinformatics2018
30349868Extreme-scale Dynamic Exploration of a Distributed Agent-based Model with the EMEWS Framework.IEEE Trans Comput Soc Syst2018
27058583Toxic Epidermal Necrolysis with Gastrointestinal Involvement: A Case Report and Review of the Literature.J Burn Care Res2017
28728997Sepsis reconsidered: Identifying novel metrics for behavioral landscape characterization with a high-performance computing implementation of an agent-based model.J Theor Biol2017
27826879Optimization and Control of Agent-Based Models in Biology: A Perspective.Bull Math Biol2017
27023391Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.PLoS One2016
27982086Gene expression in local stroma reflects breast tumor states and predicts patient outcome.Sci Rep2016
27384942Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success.Ann Biomed Eng2016
26885640Multiscale Modeling in the Clinic: Drug Design and Development.Ann Biomed Eng2016
27015816Augmenting Surgery via Multi-scale Modeling and Translational Systems Biology in the Era of Precision Medicine: A Multidisciplinary Perspective.Ann Biomed Eng2016
27079612Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility.Am J Physiol Gastrointest Liver Physiol2016
25087460An agent-based modeling framework linking inflammation and cancer using evolutionary principles: description of a generative hierarchy for the hallmarks of cancer and developing a bridge between mechanism and epidemiological data.Math Biosci2015
34765258Computational Studies of the Intestinal Host-Microbiota Interactome.Computation (Basel)2015
26594211Introduction of a Framework for Dynamic Knowledge Representation of the Control Structure of Transplant Immunology: Employing the Power of Abstraction with a Solid Organ Transplant Agent-Based Model.Front Immunol2015
26111346A Computational, Tissue-Realistic Model of Pressure Ulcer Formation in Individuals with Spinal Cord Injury.PLoS Comput Biol2015
25947163Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak.Sci Transl Med2015
25814637Integrating physiology across scales and formalizing hypothesis exploration with agent-based modeling.J Appl Physiol (1985)2015
25806784Towards anatomic scale agent-based modeling with a massively parallel spatially explicit general-purpose model of enteric tissue (SEGMEnT_HPC).PLoS One2015
24430553Removal of inflammatory ascites is associated with dynamic modification of local and systemic inflammation along with prevention of acute lung injury: in vivo and in silico studies.Shock2014
25215465Proceedings of the first international summit on intestinal anastomotic leak, Chicago, Illinois, October 4-5, 2012.Surg Infect (Larchmt)2014
25018747How implementation of systems biology into clinical trials accelerates understanding of diseases.Front Neurol2014
25168489Agent-based model of fecal microbial transplant effect on bile acid metabolism on suppressing Clostridium difficile infection: an example of agent-based modeling of intestinal bacterial infection.J Pharmacokinet Pharmacodyn2014
24768566From data patterns to mechanistic models in acute critical illness.J Crit Care2014
24675765Investigation of inflammation and tissue patterning in the gut using a Spatially Explicit General-purpose Model of Enteric Tissue (SEGMEnT).PLoS Comput Biol2014
24725600Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model.Theor Biol Med Model2014
23290531Agent-based model of epithelial host-pathogen interactions in anastomotic leak.J Surg Res2013
25022216A Systems Engineering Perspective on Homeostasis and Disease.Front Bioeng Biotechnol2013
24761337Using an Agent-Based Model to Examine the Role of Dynamic Bacterial Virulence Potential in the Pathogenesis of Surgical Site Infection.Adv Wound Care (New Rochelle)2013
24527362Computational Modeling of Inflammation and Wound Healing.Adv Wound Care (New Rochelle)2013
24501640The Hospital Microbiome Project: Meeting report for the 2nd Hospital Microbiome Project, Chicago, USA, January 15(th), 2013.Stand Genomic Sci2013
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Collaborators

University of Pittsburgh
Co-authored papers 31
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Co-authored papers 6
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 5
University of Pittsburgh
Co-authored papers 4
Co-authored papers 4
University of Pittsburgh
Co-authored papers 4
University of Pittsburgh
Co-authored papers 3
Harborview Medical Center, The University of Washington
Co-authored papers 3
McGill University
Co-authored papers 3
University of Pittsburgh Medical Center
Co-authored papers 2
Center for the Neural Basis of Cognition
Co-authored papers 2
Argonne National Laboratory
Co-authored papers 2
University of Delaware
Co-authored papers 2
University of California san francisco
Co-authored papers 2
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
Co-authored papers 2
Center for Health Services Research, Brandenburg Medical School Theodor Fontane
Co-authored papers 2
University of Southern California Keck School of Medicine
Co-authored papers 2
King Abdullah University of Science and Technology (KAUST)
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Universitat Witten/Herdecke Institute for Research in Operative Medicine (IFOM)
Co-authored papers 1
Medical Subspecialities Institute, Cleveland Clinic
Co-authored papers 1
University of Tennessee
Co-authored papers 1
Institute for Artificial Intelligence, University of Duisburg-Essen
Co-authored papers 1
University of Pittsburgh School of Medicine
Co-authored papers 1
University of California
Co-authored papers 1
Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS)
Co-authored papers 1
Hospital Clinic of Barcelona-Institut d'Investigacions
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University of California berkeley
Co-authored papers 1