Author details

Full Name

Kristopher K Frese

Affiliation

Cancer Research UK Manchester Institute, University of Manchester

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37455012	Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry.	J Thorac Oncol	2023
35091446	Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma.	Clin Cancer Res	2022
35941262	cfDNA methylome profiling for detection and subtyping of small cell lung cancers.	Nat Cancer	2022
33435818	Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories.	Open Biol	2021
33577787	Small cell lung cancer enters the era of precision medicine.	Cancer Cell	2021
34789728	Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer.	Nat Commun	2021
32721553	The Rare YAP1 Subtype of SCLC Revisited in a Biobank of 39 Circulating Tumor Cell Patient Derived Explant Models: A Brief Report.	J Thorac Oncol	2020
35121965	A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity.	Nat Cancer	2020
33221678	Brief report on the clinical characteristics of patients whose samples generate small cell lung cancer circulating tumour cell derived explants.	Lung Cancer	2020
30427531	Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics.	Br J Pharmacol	2019
31492749	Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer.	Clin Cancer Res	2019
31011204	Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.	Nat Med	2019
28077438	Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer.	Gut	2018
30191851	Will liquid biopsies improve outcomes for patients with small-cell lung cancer?	Lancet Oncol	2018
29941481	The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer.	Clin Cancer Res	2018
29951225	Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin.	NPJ Genom Med	2018
28904884	Circulating tumor cells and CDX models as a tool for preclinical drug development.	Transl Lung Cancer Res	2017
28442585	Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models.	Mol Cancer Res	2017
29133857	PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways.	Sci Rep	2017
29173760	Targeting DNA damage in SCLC.	Lung Cancer	2017
29092942	PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.	Cancer Res	2017
27013395	Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study.	Ann Oncol	2016
26347531	MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model.	Gut	2016
26669866	PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways.	Cancer Res	2016
24067278	SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice.	Gut	2014
24874484	Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo.	Br J Cancer	2014
22466618	Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.	Gut	2013
24312560	RhoC interacts with integrin Î±5Î²1 and enhances its trafficking in migrating pancreatic carcinoma cells.	PLoS One	2013
23836645	CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer.	Proc Natl Acad Sci U S A	2013
22157328	Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice.	Gut	2012
22585996	nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer.	Cancer Discov	2012
22351932	Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma.	J Exp Med	2012
20966025	Stromal biology and therapy in pancreatic cancer.	Gut	2011
22043453	C-Raf is required for the initiation of lung cancer by K-Ras(G12D).	Cancer Discov	2011
21734707	Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.	Nature	2011
21431415	A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.	Cancer Chemother Pharmacol	2011
19460966	Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.	Science	2009
17828302	Functionally distinct monomers and trimers produced by a viral oncoprotein.	Oncogene	2008
18374157	K-Ras-driven pancreatic cancer mouse model for anticancer inhibitor analyses.	Methods Enzymol	2008
17314165	A new crucial protein interaction element that targets the adenovirus E4-ORF1 oncoprotein to membrane vesicles.	J Virol	2007
17687385	Maximizing mouse cancer models.	Nat Rev Cancer	2007
16511562	Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor.	EMBO J	2006
16141229	Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells.	J Cell Sci	2005
12569363	Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein.	Oncogene	2003
14562058	Discs-Large and Strabismus are functionally linked to plasma membrane formation.	Nat Cell Biol	2003

1 - 45 of 45

Victor Olivas

University of California san francisco

Career Start Year 2012

Number of shared co-authors 2

Kien Pham

Yale School of Public Health

Career Start Year 2012

Number of shared co-authors 0

Vibha Raghavan

Princess Margaret Cancer Centre, University Health Network

Career Start Year 2009

Number of shared co-authors 0

Chad V Pecot

University of North Carolina at Chapel Hill

Career Start Year 2009

Number of shared co-authors 2

Stacey J Adam

Foundation for the National Institutes of Health

Career Start Year 2004

Number of shared co-authors 2

Jalna Meens

Princess Margaret Cancer Centre, University Health Network

Career Start Year 2004

Number of shared co-authors 0

Lixia Diao

The University of Texas MD Anderson Cancer Center

Career Start Year 2003

Number of shared co-authors 3

Elena Ivanova

Dana-Farber Cancer Institute

Career Start Year 2003

Number of shared co-authors 0

Ming Li

Princess Margaret Cancer Centre, University Health Network

Career Start Year 2003

Number of shared co-authors 0

Monte M Winslow

Stanford University School of Medicine

Career Start Year 2002

Number of shared co-authors 5

Trever G Bivona

University of California san francisco

Career Start Year 2002

Number of shared co-authors 2

Andrea Viale

The University of Texas MD Anderson Cancer Center

Career Start Year 2001

Number of shared co-authors 1

Eric A Collisson

University of California san francisco

Career Start Year 1999

Number of shared co-authors 3

Collin M Blakely

University of California san francisco

Career Start Year 1998

Number of shared co-authors 1

Nhu-An Pham

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1998

Number of shared co-authors 0

Ni Liu

Princess Margaret Cancer Centre, University Health Network, University of Toronto

Career Start Year 1997

Number of shared co-authors 1

Peter S Hammerman

Novartis Institutes for BioMedical Research

Career Start Year 1996

Number of shared co-authors 3

Michael Peyton

Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center

Career Start Year 1994

Number of shared co-authors 1

Jan Paul Medema

Oncode Institute

Career Start Year 1993

Number of shared co-authors 2

Anirban Maitra

The University of Texas MD Anderson Cancer Center

Career Start Year 1993

Number of shared co-authors 3

Nabeel Bardeesy

Massachusetts General Hospital

Career Start Year 1992

Number of shared co-authors 3

David N Watkins

Research Institute in Oncology and Hematology

Career Start Year 1991

Number of shared co-authors 2

Laurie Ailles

University of Toronto

Career Start Year 1991

Number of shared co-authors 0

E Alejandro Sweet-Cordero

University of California San Francisco

Career Start Year 1989

Number of shared co-authors 7

David S Schrump

Center for Cancer Research, National Cancer Institute

Career Start Year 1988

Number of shared co-authors 1

William C Hahn

Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute

Career Start Year 1987

Number of shared co-authors 7

Lori S Hart

Children's Hospital of Philadelphia, USA. [2] Center for Childhood Cancer Research

Career Start Year 1987

Number of shared co-authors 1

Helen J Ross

Mayo Clinic

Career Start Year 1982

Number of shared co-authors 3

David M Jablons

University of California, USA Cardiovascular Research Institute san francisco

Career Start Year 1981

Number of shared co-authors 1

Ming-Sound Tsao

University Health Network, University of Toronto

Career Start Year 1972

Number of shared co-authors 3

row(s) 1 - 30 of 30

Fiona Blackhall

The University of Manchester

Co-authored papers 12

Gina M DeNicola

H. Lee. Moffitt Cancer Center

Co-authored papers 4

William J Howat

Cancer Research UK Cambridge Institute

Co-authored papers 4

Basetti Madhu

Co-authored papers 3

Isabel Latorre

Co-authored papers 3

Martijn P Lolkema

Erasmus MC Cancer Institute

Co-authored papers 3

John R Griffiths

Co-authored papers 2

Theodore C Goldstein

Bakar Computational Health Sciences Institute, University of California san francisco

Co-authored papers 1

Atul J Butte

Bakar Computational Health Sciences Institute, University of California san francisco

Co-authored papers 1

Jos Jonkers

Oncode Institute, Netherlands Cancer Institute

Co-authored papers 1

Kent C Lloyd

University of California davis

Co-authored papers 1

Terrence F Meehan

European Bioinformatics Institute

Co-authored papers 1

Monica J Justice

The Hospital for Sick Children

Co-authored papers 1

Andrea Bertotti

Candiolo Cancer Institute - FPO IRCCS

Co-authored papers 1

Annette T Byrne

Royal College of Surgeons in Ireland (RCSI)

Co-authored papers 1

Carlos Caldas

Cancer Research UK Cambridge Institute, University of Cambridge

Co-authored papers 1

Olivier Duchamp

Co-authored papers 1

James M Olson

Clinical Research Division, Fred Hutchinson Cancer Center

Co-authored papers 1

Mark A Murakami

Dana-Farber Cancer Institute

Co-authored papers 1

Peter J Houghton

The University of Texas Health Science Center at San Antonio

Co-authored papers 1

Sebastian Brabetz

Hopp Children's Cancer Center Heidelberg (KiTZ)

Co-authored papers 1

Lifu Wang

Co-authored papers 1

Amanda L Christie

Dana-Farber Cancer Institute

Co-authored papers 1

Marcel Kool

Hopp Children's Cancer Center (KiTZ)

Co-authored papers 1

Jeremy Mason

European Molecular Biology Laboratory - European Bioinformatics Institute

Co-authored papers 1

Fr??d??ric Amant

Netherlands Cancer Institute

Co-authored papers 1

Els Hermans

Netherlands Cancer Institute

Co-authored papers 1

Thomas Helleday

The University of Sheffield

Co-authored papers 1

Stefan M Pfister

Hopp Children's Cancer Center Heidelberg (KiTZ)

Co-authored papers 1

Kristel Kemper

Oncode Institute, The Netherlands Cancer Institute

Co-authored papers 1

1 - 30

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