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Author Details
Full Name
Susmita Kaushik
Affiliation
Albert Einstein College of Medicine
ORCID
Career Start Year
2003
Papers
62
H Index
47
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
38039131
NGLY1 mutations cause protein aggregation in human neurons.
Cell Rep
2023
37831778
A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion.
Sci Adv
2023
35167431
Circadian remodeling of the proteome by chaperone-mediated autophagy.
Autophagy
2022
35363568
Protective role of chaperone-mediated autophagy against atherosclerosis.
Proc Natl Acad Sci U S A
2022
36383673
Chaperone-mediated autophagy regulates adipocyte differentiation.
Sci Adv
2022
33442062
Chaperone-mediated autophagy sustains haematopoietic stem-cell function.
Nature
2021
33891876
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Cell
2021
34876687
Reciprocal regulation of chaperone-mediated autophagy and the circadian clock.
Nat Cell Biol
2021
34563704
Autophagy and the hallmarks of aging.
Ageing Res Rev
2021
31504266
Comprehensive autophagy evaluation in cardiac disease models.
Cardiovasc Res
2020
30918111
A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.
Sci Transl Med
2019
31412041
(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells.
PLoS One
2019
29301854
Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100.
Circ Res
2018
30202070
Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.
Nat Commun
2018
29626215
The coming of age of chaperone-mediated autophagy.
Nat Rev Mol Cell Biol
2018
26902588
AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA.
Autophagy
2016
27304509
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.
Cell Metab
2016
27405763
Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy.
J Biol Chem
2016
26799652
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy
2016
25961502
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.
Nat Cell Biol
2015
26646497
Proteostasis and aging.
Nat Med
2015
22331875
Inhibitory effect of dietary lipids on chaperone-mediated autophagy.
Proc Natl Acad Sci U S A
2012
22966490
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy
2012
23059540
Chaperones in autophagy.
Pharmacol Res
2012
22748206
Chaperone-mediated autophagy: a unique way to enter the lysosome world.
Trends Cell Biol
2012
22840404
Age-related oxidative stress compromises endosomal proteostasis.
Cell Rep
2012
22249165
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis.
EMBO Rep
2012
20152936
Protein homeostasis and aging: The importance of exquisite quality control.
Ageing Res Rev
2011
22171050
Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease.
J Neurosci
2011
21803288
Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance.
Cell Metab
2011
21464620
Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.
Autophagy
2011
21238931
Microautophagy of cytosolic proteins by late endosomes.
Dev Cell
2011
21186265
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.
Brain
2011
21282471
Chaperone-mediated autophagy at a glance.
J Cell Sci
2011
20075865
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy.
EMBO J
2010
20797626
Identification of regulators of chaperone-mediated autophagy.
Mol Cell
2010
21029294
Autophagic pathways and metabolic stress.
Diabetes Obes Metab
2010
20529957
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy.
Hum Mol Genet
2010
20647740
Inhibitory effect of intracellular lipid load on macroautophagy.
Autophagy
2010
20383138
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Nat Neurosci
2010
20375270
Altered lipid content inhibits autophagic vesicular fusion.
FASEB J
2010
20026095
Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats.
Toxicol Appl Pharmacol
2010
20023429
Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation.
Autophagy
2010
19200890
Methods to monitor chaperone-mediated autophagy.
Methods Enzymol
2009
19654187
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing.
Hum Mol Genet
2009
19339967
Autophagy regulates lipid metabolism.
Nature
2009
19411822
In search of an "autophagomometer".
Autophagy
2009
18172548
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
J Clin Invest
2008
18644871
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane.
Mol Cell Biol
2008
18337468
Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy.
Mol Biol Cell
2008
1 - 50 of 62
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