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Author Details

Chunaram Choudhary
The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
2003
86
54
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37024579Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes.Nat Genet2023
37751355TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes.Cell Rep2023
37951215K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.Mol Cell2023
35575093HDAC6 modulates myofibril stiffness and diastolic function of the heart.J Clin Invest2022
33450211Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination.Mol Cell2021
33765415Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release.Mol Cell2021
33947818SIK2 orchestrates actin-dependent host response upon <i>Salmonella</i> infection.Proc Natl Acad Sci U S A2021
32395753Sequencing of the First Draft of the Human Acetylome.Clin Chem2020
31827282HBO1 is required for the maintenance of leukaemia stem cells.Nature2020
33087936Equilibrium between nascent and parental MCM proteins protects replicating genomes.Nature2020
32610040Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation.Cell Stem Cell2020
30467427Functions and mechanisms of non-histone protein acetylation.Nat Rev Mol Cell Biol2019
31296352Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry.Trends Biochem Sci2019
31267066Author Correction: Functions and mechanisms of non-histone protein acetylation.Nat Rev Mol Cell Biol2019
30837475Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation.Nat Commun2019
30975768Retraction.Science2019
30531905Acetylation of intrinsically disordered regions regulates phase separation.Nat Chem Biol2019
29656893DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.Cell2018
29804834Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.Cell2018
29876001STK3 is a therapeutic target for a subset of acute myeloid leukemias.Oncotarget2018
30485802Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint.Cell Rep2018
29523821p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.Nat Commun2018
29769713Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.Nature2018
29241531lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1.Cell Rep2017
28254776Accurate Quantification of Site-specific Acetylation Stoichiometry Reveals the Impact of Sirtuin Deacetylase CobB on the <i>E. coli</i> Acetylome.Mol Cell Proteomics2017
29123070Redox-sensitive alteration of replisome architecture safeguards genome integrity.Science2017
28953875Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.Nature2017
26904940The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity.Cell Rep2016
27462448Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover.Cell Discov2016
27307491SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.EMBO J2016
26966248Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.Genes Dev2016
26744420A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.Genes Dev2016
25585578FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51.Nat Commun2015
26358839Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions.EMBO J2015
26513550Avoiding abundance bias in the functional annotation of post-translationally modified proteins.Nat Methods2015
26327694Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.Elife2015
26503038Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.Nature2015
26502892Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae.Mol Syst Biol2015
27135800Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.Cell Syst2015
26038114Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.Mol Syst Biol2015
25751058Acetylation site specificities of lysine deacetylase inhibitors in human cells.Nat Biotechnol2015
25817432Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.Nat Commun2015
25497329Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells.DNA Repair (Amst)2015
25557546Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage.Mol Cell2015
24462288Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry.Cell Rep2014
25056879Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β.Sci Signal2014
25053359The growing landscape of lysine acetylation links metabolism and cell signalling.Nat Rev Mol Cell Biol2014
25092792UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells.EMBO Rep2014
25189701A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response.Genes Dev2014
24961812Convergence of ubiquitylation and phosphorylation signaling in rapamycin-treated yeast cells.Mol Cell Proteomics2014
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Collaborators

Wolfgang E Berdel
University Hospital Munster
Co-authored papers 13
Matthias Mann
Max-Planck Institute of Biochemistry
Co-authored papers 12
Shankha Satpathy
Co-authored papers 8
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Co-authored papers 5
J??rgen Cox
Max-Planck Institute of Biochemistry
Co-authored papers 4
Lars Juhl Jensen
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 4
Debojyoti Chakraborty
CSIR-Institute of Genomics & Integrative Biology
Co-authored papers 3
Philip A Cole
Brigham and Women's Hospital, Blavatnik Institute, Harvard Medical School
Co-authored papers 3
Wai Kit Chu
The Chinese University of Hong Kong
Co-authored papers 3
Ivan Dikic
Institute of Biochemistry II, Goethe University Frankfurt
Co-authored papers 3
Frank Buchholz
University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Co-authored papers 3
Maciej Paszkowski-Rogacz
Faculty of Medicine and University Hospital Carl Gustav Carus
Co-authored papers 3
Kenneth D Bromberg
Co-authored papers 3
Li Ding
Medical Faculty and University Hospital Carl Gustav Carus
Co-authored papers 3
Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 2
Adrian Francis Stewart
Center for Molecular and Cellular Bioengineering, Technische Universitat Dresden
Co-authored papers 2
Ronen Marmorstein
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Tamar Uziel
AbbVie Inc.
Co-authored papers 2
Michael Rehman
Institute of Biochemistry, Friedrich-Alexander-University of Erlangen-Nurnberg
Co-authored papers 2
Haruhiko Koseki
RIKEN Research Center for Allergy and Immunology
Co-authored papers 1
Sara A Wennersten
University of Colorado
Co-authored papers 1
Sukhdeep Singh
Center for Molecular and Cellular Bioengineering, University of Technology Dresden
Co-authored papers 1
Oliver M Dovey
Co-authored papers 1
Benjamin A Garcia
University of Pennsylvania
Co-authored papers 1
James E Bradner
Co-authored papers 1
Balaji S Srinivasan
Co-authored papers 1
Kasper Lage
Co-authored papers 1
Peter Walter
University of California san francisco
Co-authored papers 1
Nagarjuna Nagaraj
Bruker Daltonics GmbH & Co. KG
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