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Author Details

Han Altae-Tran
Broad Institute of Massachusetts Institute of Technology and Harvard
2013
24
15
PMIDPaper TitleJournal TitlePublished Year
37267947Modularity and diversity of target selectors in Tn7 transposons.Mol Cell2023
37995242Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering.Science2023
37983496Diversity, evolution, and classification of the RNA-guided nucleases TnpB and Cas12.Proc Natl Acad Sci U S A2023
37020030Cryo-EM structure of the transposon-associated TnpB enzyme.Nature2023
37380027Fanzor is a eukaryotic programmable RNA-guided endonuclease.Nature2023
37272862The Transposon-Encoded Protein TnpB Processes Its Own mRNA into ϿRNA for Guided Nuclease Activity.CRISPR J2023
34462587Compact RNA editors with small Cas13 proteins.Nat Biotechnol2022
36224386Structure of the OMEGA nickase IsrB in complex with ϿRNA and target DNA.Nature2022
36027912Structure and engineering of the minimal type VI CRISPR-Cas13bt3.Mol Cell2022
36344504Structure of the IscB-ϿRNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9.Nat Commun2022
34591643The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases.Science2021
33770501Dual modes of CRISPR-associated transposon homing.Cell2021
34872347Cargo Genes of Tn<i>7</i>-Like Transposons Comprise an Enormous Diversity of Defense Systems, Mobile Genetic Elements, and Antibiotic Resistance Genes.mBio2021
32848231Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing.Nat Hum Behav2020
37528961Computational Identification of Repeat-Containing Proteins and Systems.QRB Discov2020
32577674Population-scale Longitudinal Mapping of COVID-19 Symptoms, Behavior, and Testing Identifies Contributors to Continued Disease Spread in the United States.medRxiv2020
32855333Diverse enzymatic activities mediate antiviral immunity in prokaryotes.Science2020
32591764Publisher Correction: Building an international consortium for tracking coronavirus health status.Nat Med2020
28052137Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.PLoS Pathog2017
28470045Low Data Drug Discovery with One-Shot Learning.ACS Cent Sci2017
24590074Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.Nature2014
25211073Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.Cell Host Microbe2014
23661761Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.Science2013
23911655Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies.Immunity2013
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Collaborators

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Zuckerman Mind Brain Behaviour Institute
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Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
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Harvard T.H. Chan School of Public Health
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National Human Genome Research Institute, National Institutes of Health
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Stanford University
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University of Maryland
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Institute of Computer Science, University of Tartu
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