Author details

Full Name

Kelly V Ruggles

Affiliation

ORCID

Career Start Year

2009

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36729813	Pathogen-Specific Alterations in the Gut Microbiota Predict Outcomes in Flare of Inflammatory Bowel Disease Complicated by Gastrointestinal Infection.		2023
36245285	Platelet LGALS3BP as a Mediator of Myeloid Inflammation in Systemic Lupus Erythematosus.	Arthritis and Rheumatology	2023
37604357	Biomarkers and cardiovascular events in patients with stable coronary disease in the ISCHEMIA Trials.	Am Heart J	2023
36909517	Single-cell analysis of CX3CR1 cells reveal a pathogenic role for BIRC5 myeloid proliferating cells driven by leukotoxins.		2023
37029410	Modeling of clinical phenotypes in systemic lupus erythematosus based on the platelet transcriptome and FCGR2a genotype.		2023
37466391	Single-Cell Analysis of CX3CR1+ Cells Reveals a Pathogenic Role for BIRC5+ Myeloid Proliferating Cells Driven by Staphylococcus aureus Leukotoxins.		2023
37394063	PhosphoDisco: A Toolkit for Co-regulated Phosphorylation Module Discovery in Phosphoproteomic Data.	Mol Cell Proteomics	2023
36747851	The Sin3B chromatin modifier restricts cell cycle progression to dictate hematopoietic stem cell differentiation.		2023
37435512	Syndemic factors associated with non-fatal overdose among young opioid users in New York City.		2023
36924033	An inflammatory transcriptomic signature in psoriasis associates with future cardiovascular events.		2023
35262173	Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis.	Cancer Discov	2022
35881802	<i>Staphylococcus aureus</i> induces a muted host response in human blood that blunts the recruitment of neutrophils.	Proc Natl Acad Sci U S A	2022
35749506	Translational regulation of TFH cell differentiation and autoimmune pathogenesis.	Sci Adv	2022
36198790	The Î³Î´ IEL effector API5 masks genetic susceptibility to Paneth cell death.	Nature	2022
36450245	Clostridia isolated from helminth-colonized humans promote the life cycle of Trichuris species.	Cell Rep	2022
35468922	Risk factors, transcriptomics, and outcomes of myocardial injury following lower extremity revascularization.	Sci Rep	2022
34538015	Platelets contribute to disease severity in COVID-19.	J Thromb Haemost	2021
34289377	Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice.	Cell Host Microbe	2021
33746917	Predictive Metagenomic Analysis of Autoimmune Disease Identifies Robust Autoimmunity and Disease Specific Microbial Signatures.	Frontiers in Microbiology	2021
34232982	Multimodal single-cell analysis of cutaneous T-cell lymphoma reveals distinct subclonal tissue-dependent signatures.	Blood	2021
34165986	BlackSheep: A Bioconductor and Bioconda Package for Differential Extreme Value Analysis.	J Proteome Res	2021
33577785	Proteogenomic and metabolomic characterization of human glioblastoma.	Cancer Cell	2021
34055961	Adverse Childhood Experiences Predict Early Initiation of Opioid Use Behaviors.	Frontiers in Sociology	2021
33737451	Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus.	Lupus Sci Med	2021
33622961	A comparative analysis of SARS-CoV-2 antivirals characterizes 3CL inhibitor PF-00835231 as a potential new treatment for COVID-19.	Journal of Virology	2021
33875650	Spatially interacting phosphorylation sites and mutations in cancer.	Nat Commun	2021
33769280	Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease.	Elife	2021
33720008	Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.	Elife	2021
33657880	Gene Expression Signature in Patients With Symptomatic Peripheral Artery Disease.	Arteriosclerosis, Thrombosis, and Vascular Biology	2021
33438219	Drug Transaction Experiences in American High Schools 2001-2015.	Journal of School Health	2021
34355145	Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression.	iScience	2021
33359089	Single-Cell Transcriptional Survey of Ileal-Anal Pouch Immune Cells From Ulcerative Colitis Patients.	Gastroenterology	2021
34516880	Platelets amplify endotheliopathy in COVID-19.	Sci Adv	2021
33152268	Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase Îµ.	Molecular Cell	2020
32350082	Distinct Features of Human Myeloid Cell Cytokine Response Profiles Identify Neutrophil Activation by Cytokines as a Prognostic Feature during Tuberculosis and Cancer.	J Immunol	2020
31923397	Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.	Cell	2020
32209431	Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition.		2020
32993491	Hypercluster: a flexible tool for parallelized unsupervised clustering optimization.	BMC Bioinformatics	2020
31196969	Regulated Phosphosignaling Associated with Breast Cancer Subtypes and Druggability.	Mol Cell Proteomics	2019
31675502	Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.	Cell	2019
30102568	Loss of HDAC6 alters gut microbiota and worsens obesity.	FASEB Journal	2019
29320347	Heroin Use and Drug Injection among Youth Also Misusing Prescription Drugs.		2018
30076308	A widespread alternate form of cap-dependent mRNA translation initiation.	Nature Communications	2018
30158281	Changes in the Gut Microbiota of Urban Subjects during an Immersion in the Traditional Diet and Lifestyle of a Rainforest Village.	mSphere	2018
30349875	Evaluating Alternative Designs of a Multilevel HIV Intervention in Maharashtra, India: The Impact of Stakeholder Constraints.	MDM Policy Pract	2018
30325954	A genomic ruler to assess oncogenic transition between breast tumor and stroma.	PLoS ONE	2018
30039798	Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity.	Elife	2018
29940835	WHAM!: a web-based visualization suite for user-defined analysis of metagenomic shotgun sequencing data.	BMC Genomics	2018
30409155	RIVET: comprehensive graphic user interface for analysis and exploration of genome-wide translatomics data.	BMC Genomics	2018
29527592	Data Science in the Research Domain Criteria Era: Relevance of Machine Learning to the Study of Stress Pathology, Recovery, and Resilience.	Chronic Stress	2018