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Author Details

Norihito Shibata
2001
48
26
PMIDPaper TitleJournal TitlePublished Year
37523332Providing appropriate information to consumers boosts the acceptability of genome-edited foods in Japan.2023
37018877CRBN ligand expansion for hematopoietic prostaglandin D synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles.2023
37121697Rapid Screening Detection of Genetically Modified Papaya by Loop-Mediated Isothermal Amplification.2023
35085722Development of a degrader against oncogenic fusion protein FGFR3-TACC3.Bioorganic and Medicinal Chemistry Letters2022
36181413Unbiased prediction of off-target sites in genome-edited rice using SITE-Seq analysis on a web-based platform.Genes to Cells2022
35822913Development of Rapid and Facile Solid-Phase Synthesis of PROTACs via a Variety of Binding Styles.ChemistryOpen2022
36154001Development and Interlaboratory Validation of a Novel Reproducible Qualitative Method for GM Soybeans Using Comparative Cq-Based Analysis for the Revised Non-GMO Labeling System in Japan.Analytical Chemistry2022
35743289Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues.International Journal of Molecular Sciences2022
36205585Development and Validation of a New Robust Detection Method for Low-Content DNA Using οοCq-Based Real-Time PCR with Optimized Standard Plasmids as a Control Sample.Analytical Chemistry2022
36561070Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D synthase.2022
34652145Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design.Journal of Medicinal Chemistry2021
33603969Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer.ACS Medicinal Chemistry Letters2021
34432253Protocols for Synthesis of SNIPERs and the Methods to Evaluate the Anticancer Effects.Methods in Molecular Biology2021
32203161Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells.Oncogene2020
31303986Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues.MedChemComm2019
31921772Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs.Frontiers in Chemistry2019
30369550Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER).Chemical and Pharmaceutical Bulletin2019
31200857SNIPERs-Hijacking IAP activity to induce protein degradation.Drug Discovery Today: Technologies2019
30827996Development of a Potent Protein Degrader against Oncogenic BCR-ABL Protein.Chemical and Pharmaceutical Bulletin2019
29545311Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation.Journal of Biological Chemistry2018
28594553Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.Journal of Medicinal Chemistry2018
30202081Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase.Scientific Reports2018
29205725Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy.Genes to Cells2018
28192613SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.Cancer Science2017
28556300Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands.Cancer Science2017
28807436Simple and efficient knockdown of His-tagged proteins by ternary molecules consisting of a His-tag ligand, a ubiquitin ligase ligand, and a cell-penetrating peptide.Bioorganic and Medicinal Chemistry Letters2017
29057048Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation.ACS Medicinal Chemistry Letters2017
28154167Knockdown of Pathogenic Proteins via pecific and ongenetic nhibitor of Apoptosis Protein (IAP)-dependent rotein asers (SNIPERs).Journal of Biological Chemistry2017
27965304Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.Molecular Pharmacology2017
27666635Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand.Bioorganic and Medicinal Chemistry Letters2016
26560118Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy.Current Cancer Drug Targets2016
26585163Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα.Methods in Molecular Biology2016
26442586Degradation of Stop Codon Read-through Mutant Proteins via the Ubiquitin-Proteasome System Causes Hereditary Disorders.J Biol Chem2015
25375378Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway.Cell Death and Disease2014
2418906925-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.J Biol Chem2013
23992566Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.Cancer Science2013
23021221Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.Cell2012
22740812Gastric ulcer associated with cytomegalovirus in an immunocompetent patient: method for diagnosis.Case Reports in Gastroenterology2012
20838002Macrophages, oxysterols and atherosclerosis.Circ J2010
18987388Regulation of macrophage function in inflammation and atherosclerosis.J Lipid Res2009
17586471Scavenger receptor expressed by endothelial cells (SREC)-I interacts with protein phosphatase 1alpha in L cells to induce neurite-like outgrowth.Biochemical and Biophysical Research Communications2007
16741291Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver.Journal of Lipid Research2006
17077281Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis.FASEB Journal2006
16174736Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.Proceedings of the National Academy of Sciences of the United States of America2005
16098143Inhibition of cholesterol biosynthesis by 25-hydroxycholesterol is independent of OSBP.Genes to Cells2005
16014812Vitamin E is essential for mouse placentation but not for embryonic development itself.Biology of Reproduction2005
15247299Type F scavenger receptor SREC-I interacts with advillin, a member of the gelsolin/villin family, and induces neurite-like outgrowth.Journal of Biological Chemistry2004
11226224Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis.Proceedings of the National Academy of Sciences of the United States of America2001
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